262,996 research outputs found
Scaling of nuclear modification factors for hadrons and light nuclei
The number of constituent quarks (NCQ-) scaling of hadrons and the number of
constituent nucleons (NCN-) scaling of light nuclei are proposed for nuclear
modification factors () of hadrons and light nuclei, respectively,
according to the experimental investigations in relativistic heavy-ion
collisions. Based on coalescence mechanism the scalings are performed for pions
and protons in quark level, and light nuclei and He for
nucleonic level, respectively, formed in Au + Au and Pb + Pb collisions and
nice scaling behaviour emerges. NCQ or NCN scaling law of can be
respectively taken as a probe for quark or nucleon coalescence mechanism for
the formation of hadron or light nuclei in relativistic heavy-ion collisions.Comment: 6 pages, 6 figure
A refined invariant subspace method and applications to evolution equations
The invariant subspace method is refined to present more unity and more
diversity of exact solutions to evolution equations. The key idea is to take
subspaces of solutions to linear ordinary differential equations as invariant
subspaces that evolution equations admit. A two-component nonlinear system of
dissipative equations was analyzed to shed light on the resulting theory, and
two concrete examples are given to find invariant subspaces associated with
2nd-order and 3rd-order linear ordinary differential equations and their
corresponding exact solutions with generalized separated variables.Comment: 16 page
Epigenetics in Friedreich's ataxia: Challenges and opportunities for therapy
Copyright © 2013 Chiranjeevi Sandi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Friedreich's ataxia (FRDA) is an autosomal recessive neurodegenerative disorder caused by homozygous expansion of a GAA·TTC trinucleotide repeat within the first intron of the FXN gene, leading to reduced FXN transcription and decreased levels of frataxin protein. Recent advances in FRDA research have revealed the presence of several epigenetic modifications that are either directly or indirectly involved in this FXN gene silencing. Although epigenetic marks may be inherited from one generation to the next, modifications of DNA and histones can be reversed, indicating that they are suitable targets for epigenetic-based therapy. Unlike other trinucleotide repeat disorders, such as Huntington disease, the large expansions of GAA·TTC repeats in FRDA do not produce a change in the frataxin amino acid sequence, but they produce reduced levels of normal frataxin. Therefore, transcriptional reactivation of the FXN gene provides a good therapeutic option. The present paper will initially focus on the epigenetic changes seen in FRDA patients and their role in the silencing of FXN gene and will be concluded by considering the potential epigenetic therapies.This study is supported by funding from the European Union Seventh Framework Programme (FP7/2007–2013) under Grant agreement no. 242193/EFACTS; and by funding from theWellcome Trust (089757)
Ground State Energy for Fermions in a 1D Harmonic Trap with Delta Function Interaction
Conjectures are made for the ground state energy of a large spin 1/2 Fermion
system trapped in a 1D harmonic trap with delta function interaction. States
with different spin J are separately studied. The Thomas-Fermi method is used
as an effective test for the conjecture.Comment: 4 pages, 3 figure
Lensed Arcs and Inner Structure of Abell 697
We present new optical observations of the z=0.282 cluster Abell 697 from the
Keck II telescope. Images show an unusual disturbed structure in the cD halo
and a previously unknown faint gravitational lens arc. A spectrum of the arc
did not yield a redshift, but its spectrum and colors suggest it lies at z>1.3.
We construct models to reproduce the arc that show the potential is likely to
be highly elliptical. We suggest that this cluster may have undergone a recent
merger and is in the process of forming its cD galaxy. Analysis of X-ray data
from ROSAT and ASCA suggests that the merging process is sufficiently advanced
that the gas in the cluster has relaxed, and A697 lies near the L_x-T_x
relation for normal clusters.Comment: LaTeX; 12 pages, 3 figures, submitted to ApJ Letter
Neutrino Mass from Triplet and Doublet Scalars at the TeV Scale
If the minimal standard model of particle interactions is extended to include
a scalar triplet with lepton number and a scalar doublet with ,
neutrino masses eV is possible,
where GeV is the electroweak symmetry breaking scale,
TeV is the typical mass of the new scalars, and GeV is a soft
lepton-number-violating parameter.Comment: 6 pages, no figur
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