14,702 research outputs found
A multimedia package for patient understanding and rehabilitation of non-contact anterior cruciate ligament injuries
Non-contact anterior cruciate ligament (ACL) injury is one of the most common ligament injuries in the body. Many patientsā receive graft surgery to repair the damage, but have to undertake an extensive period of rehabilitation. However, non-compliance and lack of understanding of the injury, healing process and rehabilitation means patientās return to activities before effective structural integrity of the graft has been reached. When clinicians educate the patient, to encourage compliance with treatment and rehabilitation, the only tools that are currently widely in use are static plastic models, line diagrams and pamphlets. As modern technology grows in use in anatomical education, we have developed a unique educational and training package for patientās to use in gaining a better understanding of their injury and treatment plan. We have combined cadaveric dissections of the knee (and captured with high resolution digital images) with reconstructed 3D modules from the Visible Human dataset, computer generated animations, and images to produce a multimedia package, which can be used to educate the patient in their knee anatomy, the injury, the healing process and their rehabilitation, and how this links into key stages of improving graft integrity. It is hoped that this will improve patient compliance with their rehabilitation programme, and better long-term prognosis in returning to normal or near-normal activities. Feedback from healthcare professionals about this package has been positive and encouraging for its long-term use
Jefferson Digital Commons quarterly report: October-December 2019
This quarterly report includes: Articles Dean\u27s Research Development Lunch Conference Dissertations Educational Materials From the Archives Grand Rounds and Lectures Journals and Newsletters Population Health Presentation Materials Posters Reports Symposiums What People are Saying About the Jefferson Digital Common
Jefferson Digital Commons quarterly report: January-March 2020
This quarterly report includes: New Look for the Jefferson Digital Commons Articles COVID-19 Working Papers Educational Materials From the Archives Grand Rounds and Lectures JeffMD Scholarly Inquiry Abstracts Journals and Newsletters Master of Public Health Capstones Oral Histories Posters and Conference Presentations What People are Saying About the Jefferson the Digital Common
Mycotic aneurysm of the inferior gluteal artery caused by non-typhi Salmonella in a man infected with HIV: a case report
<p>Abstract</p> <p>Introduction</p> <p>Non-typhi <it>Salmonellae </it>infections represent major opportunistic pathogens affecting human immunodeficiency virus-infected individuals residing in sub-Saharan Africa. To the best of our knowledge, we report the first documented case in the medical literature of a <it>Salmonella</it>-induced mycotic aneurysm involving an artery supplying the gluteal region.</p> <p>Case presentation</p> <p>A 37-year-old black, Kenyan man, infected with human immunodeficiency virus with a CD4 count of 132 cells per microliter presented with a pulsatile gluteal mass and debilitating pain progressing over one week. He was receiving prophylaxis with trimethoprim-sulfamethoxazole. Aspiration of the mass yielded gross blood. An ultrasound examination revealed a 37 ml vascular structure with an intra-luminal clot. Upon exploration, a true aneurysm of the inferior gluteal artery was identified and successfully resected. A culture of the aspirate grew a non-typhi <it>Salmonellae </it>species. Following resection, he was treated with oral ciprofloxacin for 10 weeks. He later began anti-retroviral therapy. Forty-two months after the initial diagnosis, he remained alive and well.</p> <p>Conclusions</p> <p>Clinicians caring for patients infected with human immunodeficiency virus in Africa and other resource-limited settings should be aware of the invasive nature of <it>Salmonella </it>infections and the potential for aneurysm formation in unlikely anatomical locations. Rapid initiation of appropriate anti-microbial chemotherapy and surgical referral is needed. Use of trimethoprim-sulfamethoxazole prophylaxis does not routinely prevent invasive <it>Salmonella </it>infections.</p
The peculiar velocity field: constraining the tilt of the Universe
A large bulk flow, which is in tension with the Lambda Cold Dark Matter
(CDM) cosmological model, has been observed. In this paper, we provide
a physically plausible explanation of this bulk flow, based on the assumption
that some fraction of the observed dipole in the cosmic microwave background is
due to an intrinsic fluctuation, so that the subtraction of the observed dipole
leads to a mismatch between the cosmic microwave background (CMB) defined rest
frame and the matter rest frame. We investigate a model that takes into account
the relative velocity (hereafter the tilted velocity) between the two frames,
and develop a Bayesian statistic to explore the likelihood of this tilted
velocity.
By studying various independent peculiar velocity catalogs, we find that: (1)
the magnitude of the tilted velocity is around 400 km/s, and its direction
is close to what is found from previous bulk flow analyses; for most catalogs
analysed, u=0 is excluded at about the level;(2) constraints on
the magnitude of the tilted velocity can result in constraints on the duration
of inflation, due to the fact that inflation can neither be too long (no dipole
effect) nor too short (very large dipole effect); (3) Under the assumption of a
super-horizon isocurvature fluctuation, the constraints on the tilted velocity
require that inflation lasts at least 6 e-folds longer (at the 95% confidence
interval) than that required to solve the horizon problem. This opens a new
window for testing inflation and models of the early Universe from observations
of large scale structure.Comment: 7 pages, 7 figures, match the published version in Phys.Rev.
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