COVID-19 Pandemic and IBS. Results of the All-Russian Observational Non-interventional Program to Study the Effectiveness of the Drug Kolofort® in Real Clinical Practice in Patients with Irritable Bowel Syndrome After a New Coronavirus Infection (VESNA)

Aim: to study the effectiveness and safety of using the drug Kolofort® in outpatients with irritable bowel syndrome (IBS) after a new coronavirus infection.Materials and methods. An observational non-interventional program was conducted in patients with exacerbation of IBS symptoms after a new coronavirus infection. One hundred forty-one patients took part in the study. The final efficacy analysis included data from 127 study participants. All patients complained of increased/appearing gastrointestinal symptoms that appeared within 1–6 months after the infection (all patients had a history of COVID-19 infection). To assess the presence and severity of symptoms of the disease, the “7 × 7” questionnaire was used before the start of treatment and three months after the start of treatment.Results. At the stage of inclusion in the program, the average total score on the “7 × 7” questionnaire was 17.36, which corresponded to a moderately severe disorder. During the treatment period, the average total score decreased to 6.14, which corresponded to borderline disorder. In addition, significant improvement was observed for each symptom separately. After three months of therapy, doctors rated the overall impression of the treatment on a 5-point Likert scale from “very effective” to “ineffective”. The average score was 4.24. In addition, no serious adverse events were identified while taking the drug.Conclusion. In real clinical practice, the drug Kolofort® demonstrated high clinical efficacy in the treatment of patients with IBS after COVID-19 infection

Producing unschoolers: Learning through living in a U.S. education movement

In this study, I explore some of the inherent and lived tensions or paradoxes produced through the principles and practices of the governmental and educational contexts of the neoliberal milieu, through the lens of a contemporary countercultural movement. In the particularities of this movement, a community of practice known to insiders as the “unschooling movement,” families seek to challenge the rationalization and standardization that they perceive as rampant and objectionable in state-overseen education. This is an ethnographic study of the countercultural praxis and identities entailed in cultivating unschooled children through distinctive childhood, familial, and community-based experiences. I consider dimensions of lifestyle that include attachment parenting, the organization of space and time, consumption, community-based education and legitimation (portfolio evaluations) to prove educational equivalance. This study reveals the hidden resources of social capital and educational capital used to sustain a countercultural educational alternative