Impact origin of the Sudbury structure: Evolution of a theory

This paper reviews the origin, development, and present status of the widely accepted theory, proposed by Robert S. Dietz in 1962, that the Sudbury structure was formed by meteoritic or asteroidal impact. The impact theory for the origin of the Sudbury structure seems supported by a nearly conclusive body of evidence. However, even assuming an impact origin to be correct, at least three major questions require further study: (1) the original size and shape of the crater, before tectonic deformation and erosion; (2) the source of the melt now forming the Sudbury Igneous Complex; and (3) the degree, if any, to which the Ni-Cu-platinum group elements are meteoritic. The history of the impact theory illustrates several under-appreciated aspects of scientific research: (1) the importance of cross-fertilization between space research and terrestrial geology; (2) the role of the outsider in stimulating thinking by insiders; (3) the value of small science, at least in the initial stages of an investigation, Dietz's first field work having been at his own expense; and (4) the value of analogies (here, between the Sudbury Igneous Complex and the maria), which although incorrect in major aspects, may trigger research on totally new lines. Finally, the Sudbury story illustrates the totally unpredictable and, by implication, unplannable nature of basic research, in that insight to the origin of the world's then-greatest Ni deposit came from the study of tektites and the Moon

Lunar Limb Observatory: An Incremental Plan for the Utilization, Exploration, and Settlement of the Moon

This paper proposes a comprehensive incremental program, Lunar Limb Observatory (LLO), for a return to the Moon, beginning with robotic missions and ending with a permanent lunar settlement. Several recent technological developments make such a program both affordable and scientifically valuable: robotic telescopes, the Internet, light-weight telescopes, shared- autonomy/predictive graphics telerobotic devices, and optical interferometry systems. Reasons for focussing new NASA programs on the Moon include public interest, Moon-based astronomy, renewed lunar exploration, lunar resources (especially helium-3), technological stimulus, accessibility of the Moon (compared to any planet), and dispersal of the human species to counter predictable natural catastrophes, asteroidal or cometary impacts in particular. The proposed Lunar Limb Observatory would be located in the crater Riccioli, with auxiliary robotic telescopes in M. Smythii and at the North and South Poles. The first phase of the program, after site certification, would be a series of 5 Delta-launched telerobotic missions to Riccioli (or Grimaldi if Riccioli proves unsuitable), emplacing robotic telescopes and carrying out surface exploration. The next phase would be 7 Delta-launched telerobotic missions to M. Smythii (2 missions), the South Pole (3 missions), and the North Pole (2 missions), emplacing robotic telescopes to provide continuous all-sky coverage. Lunar base establishment would begin with two unmanned Shuttle/Fitan-Centaur missions to Riccioli, for shelter emplacement, followed by the first manned return, also using the Shuttle/Fitan-Centaur mode. The main LLO at Riccioli would then be permanently or periodically inhabited, for surface exploration, telerobotic rover and telescope operation and maintenance, and support of Earth-based student projects. The LLO would evolve into a permanent human settlement, serving, among other functions, as a test area and staging base for the exploration, settlement, and terraforming of Mars

Pervasive Layering in the Lunar Highland Crust: Evidence from Apollos 15, 16,and 17

This paper presents results of a photogeologic reconnaissance of 70 mm photographs taken on the lunar surface during the Apollo 15, 16, and 17 missions, whose primary objective was to investigate the lunar highland crust. Photographs at all three sites, notably the Apennine Front, show pervasive layered structure. These layers are easily distinguished from lighting artifacts, and are considered genuine crustal structures. Their number, thickness, and extent implies that they are lava flows, not ejecta blankets or intrusive features. They appear to be the upper part of the earliest lunar crust, possibly forming a layer tens of kilometers thick. Remote sensing studies (X-ray fluorescence and reflectance spectroscopy), indicate that the highland crust is dominantly a feldspathic basalt. It is concluded that the highland layers represent a global crust formed by eruptions of high-alumina basalt in the first few hundred million years of the Moon's history

Global Seismicity: Three New Maps Compiled with Geographic Information Systems

This paper presents three new maps of global seismicity compiled from NOAA digital data, covering the interval 1963-1998, with three different magnitude ranges (mb): greater than 3.5, less than 3.5, and all detectable magnitudes. A commercially available geographic information system (GIS) was used as the database manager. Epicenter locations were acquired from a CD-ROM supplied by the National Geophysical Data Center. A methodology is presented that can be followed by general users. The implications of the maps are discussed, including the limitations of conventional plate models, and the different tectonic behavior of continental vs. oceanic lithosphere. Several little-known areas of intraplate or passive margin seismicity are also discussed, possibly expressing horizontal compression generated by ridge push

The role of truck wash practices in dissemination of Salmonella and Campylobacter in commercial swine production

This study investigated the sources of two foodborne pathogens, Salmonella and Campylobacter in a commercial swine production system. Pathogens were characterized using conventional culture and isolation techniques and antibiograms

New Investigations of the Alleged Meteorite from Igast, Estonia

This paper presents the results of a reinvestigation of the object which allegedly fell at Igast, Estonia, in 1855, and which may be the only example of a meteorite with the chemical composition of a tektite. R is concluded that generally quoted opinions of the artificial nature of this object are based on spurious samples, specifically melted brick and quartz basalt porphyry distributed by a Russian collector. Possibly genuine specimens from this observed fall are in the British Museum, the Paris Museum, and perhaps at the University of Dorpat, Estonia. It is recommended that these specimens be re-examined and that a search for similar objects be made

A Digital Tectonic Activity Map of the Earth

The subject of neotectonics, covering the structures and structural activity of the last 5 million years (i.e., post-Miocene) is a well-recognized field, including "active tectonics," focussed on the last 500,000 years in a 1986 National Research Council report of that title. However, there is a cartographic gap between tectonic maps, generally showing all features regardless of age, and maps of current seismic or volcanic activity. We have compiled a map intended to bridge this gap, using modern data bases and computer-aided cartographic techniques. The maps presented here are conceptually descended from an earlier map showing tectonic and volcanic activity of the last one million years. Drawn by hand with the National Geographic Society's 1975 "The Physical World" map as a base, the 1981 map in various revisions has been widely reproduced in textbooks and various technical publications. However, two decades of progress call for a completely new map that can take advantage of new knowledge and cartographic techniques. The digital tectonic activity map (DTM), presented in shaded relief (Fig. 1) and schematic (Fig. 2) versions, is the result. The DTM is intended to show tectonism and volcanism of the last one million years, a period long enough to be representative of global activity, but short enough that features such as fault scarps and volcanos are still geomorphically recognizable. Data Sources and Cartographic Methods The DTM is based on a wide range of sources, summarized in Table 1. The most important is the digital elevation model, used to construct a shaded relief map. The bathymetry is largely from satellite altimetry, specifically the marine gravity compilations by Smith and Sandwell (1996). The shaded relief map was designed to match the new National Geographic Society world physical map (1992), although drawn independently, from the digital elevation model. The Robinson Projection is used instead of the earlier Van der Grinten one. Although neither conformal nor equal-area, the Robinson Projection provides a reasonable compromise and retains useful detail at high latitudes

Restoration of Apollo Data by the NSSDC and the PDS Lunar Data Node

The Lunar Data Node (LDN), under the auspices of the Geosciences Node of the Planetary Data System (PDS), is restoring Apollo data archived at the National Space Science Data Center. The Apollo data were arch ived on older media (7 -track tapes. microfilm, microfiche) and in ob solete digital formats, which limits use of the data. The LDN is maki ng these data accessible by restoring them to standard formats and archiving them through PDS. The restoration involves reading the older m edia, collecting supporting data (metadata), deciphering and understa nding the data, and organizing into a data set. The data undergo a pe er review before archive at PDS. We will give an update on last year' s work. We have scanned notebooks from Otto Berg, P.1. for the Lunar Ejecta and Meteorites Experiment. These notebooks contain information on the data and calibration coefficients which we hope to be able to use to restore the raw data into a usable archive. We have scanned Ap ollo 14 and 15 Dust Detector data from microfilm and are in the proce ss of archiving thc scans with PDS. We are also restoring raw dust de tector data from magnetic tape supplied by Yosio Nakamura (UT Austin) . Seiichi Nagihara (Texas Tech Univ.) and others in cooperation with NSSDC are recovering ARCSAV tapes (tapes containing raw data streams from all the ALSEP instruments). We will be preparing these data for archive with PDS. We are also in the process of recovering and archivi ng data not previously archived, from the Apollo 16 Gamma Ray Spectro meter and the Apollo 17 Infrared Spectrometer

Science exploration opportunities for manned missions to the Moon, Mars, Phobos, and an asteroid

Scientific exploration opportunities for human missions to the Moon, Phobos, Mars, and an asteroid are addressed. These planetary objects are of prime interest to scientists because they are the accessible, terresterial-like bodies most likely to be the next destinations for human missions beyond Earth orbit. Three categories of science opportunities are defined and discussed: target science, platform science, and cruise science. Target science is the study of the planetary object and its surroundings (including geological, biological, atmospheric, and fields and particle sciences) to determine the object's natural physical characteristics, planetological history, mode of origin, relation to possible extant or extinct like forms, surface environmental properties, resource potential, and suitability for human bases or outposts. Platform science takes advantage of the target body using it as a site for establishing laboratory facilities and observatories; and cruise science consists of studies conducted by the crew during the voyage to and from a target body. Generic and specific science opportunities for each target are summarized along with listings of strawman payloads, desired or required precursor information, priorities for initial scientific objectives, and candidate landing sites. An appendix details the potential use of the Moon for astronomical observatories and specialized observatories, and a bibliography compiles recent work on topics relating to human scientific exploration of the Moon, Phobos, Mars, and asteroids. It is concluded that there are a wide variety of scientific exploration opportunities that can be pursued during human missions to planetary targets but that more detailed studies and precursor unmanned missions should be carried out first

Use of Quantitative Pharmacology in the Development of HAE1, a High-Affinity Anti-IgE Monoclonal Antibody

HAE1, a high-affinity anti-IgE monoclonal antibody, is discussed here as a case study in the use of quantitative pharmacology in the development of a second-generation molecule. In vitro, preclinical, and clinical data from the first-generation molecule, omalizumab, were heavily leveraged in the HAE1 program. A preliminary mechanism-based pharmacokinetic/pharmacodynamic (PK/PD) model for HAE1 was developed using an existing model for omalizumab, together with in vitro binding data for HAE1 and omalizumab. When phase I data were available, the model was refined by simultaneously modeling PK/PD data from omalizumab studies with the available HAE1 phase I data. The HAE1 clinical program was based on knowledge of the quantitative relationship between a pharmacodynamic biomarker, suppression of free IgE, and clinical response (e.g., lower exacerbation rates) obtained in pivotal studies with omalizumab. A clinical trial simulation platform was developed to predict free IgE levels and clinical responses following attainment of a target free IgE level (≤10 IU/ml). The simulation platform enabled selection of four doses for the phase II dose-ranging trial by two independent methods: dose-response non-linear fitting and linear mixed modeling. Agreement between the two methods provided confidence in the doses selected. Modeling and simulation played a large role in supporting acceleration of the HAE1 program by enabling data-driven decision-making, often based on confirmation of projections and/or learning from incoming new data