Caractéristiques des atteintes cardiaques au cours de l'immunodéficience liée au VIH en Afrique Centrale: évolution naturelle

Doctorat en sciences médicalesinfo:eu-repo/semantics/nonPublishe

Surveillance de l'endometre sous traitement hormonal de substitution par echo-Doppler

Objectives: To determine endometrial thickness, uterine and endometrial blood flow in postmenopausal women receiving hormone replacement therapy (HRT). Study design: forty hundred forty eight women were divided into six groups based on HRT. The endometrial thickness of all of them were examinated with Aloka 2000 and pulsatility and resistance index of uterine and endometrial arteries (if visible) were calculated. P < 0.05 was considered as significative. Result: The endometrial thickness was 2.8 mm ± 2.6 in group without HRT (n = 168), this endometrial thickness was significatively (p < 0.0001) lower than group with oestrogen alone: 8.7 mm ± 6, HRT sequential: 6.7 mm ± 3, HRT continous: 4 mm ± 3.1 (p<0.01), Progestagen alone: 8 mm ± 5.8 and Tibolone 6.7 mm ± 4. The mean RIs and PIs of uterine arteries are significantly lower in women receiving HRT (group 2-6) than women without HRT (0.72 ± 0.12 versus 0.92 ± 0.01) p < 0.01 and 2.16 ± 0.8 versus 2.46 ± 0.8 p < 0.01. The endometrial PI of 1.17 ± 0.4 in the HRT group was not significantly different from that in the no HRT group (1.85 ± 0.4) p = 0.06. Conclusion: The endometrial thickness was considerably lower with continous hormone replacement therapy around 4 mm. Moderate endometrial blood flow were present in all groups. The color doppler ultrasound reflects the hormonal status and change in the uterine and endometrial perfusion depending on hormonal therapy.SCOPUS: re.jinfo:eu-repo/semantics/publishe

Doppler couleur energie au cours du cycle menstruel

Doppler ultrasonography has been used over the last few years to investigate uteroovarian hemodynamics during the menstrual cycle in women and in nonhuman primates. In the present study, pulsed and energy Doppler imaging was used to determine the PI and RI values of the arcuate, radial, and endometrial uterine arteries and ovarian stroma on days 9, 12, 15, 23, and 26 of the menstrual cycle in ten young volunteers. Cycles were classified as ovulatory (n = 7) or nonovulatory (n = 3) based on the temperature curve and on whether a corpus luteum was visible upon ultrasonography. PI and RI values of the arcuate and radial uterine arteries on the dominant side were significantly lower during the luteal phase than during the follicular phase (P < 0.05). Only during ovulatory cycles were the endometrial arteries visualized during the luteal phase. Thickness of the endometrium was positively correlated with endometrial PI and RI values (r = 0.47; P < 0.01). Perifollicular flows were visualized on day 9 during both ovulatory and nonovulatory cycles. No significant differences were found in perifollicular PI and RI values between the dominant side and the nondominant side; neither were significant differences found in anovulatory cycle PI and RI values between the right side and the left side. PI values for ovarian stroma arteries on the side of ovulation decreased throughout the cycle, from 1.36 ± 0.28 on D9 to 1.25 ± 0.82 on D23 and 1 ± 0.21 on D26; the decrease was less marked on the opposite side. Pulsed and energy Doppler imaging demonstrates endometrial vascularization and increased blood flows in the ovarian stroma and corpus luteum indicating better perfusion during ovulatory cycles.SCOPUS: ar.jinfo:eu-repo/semantics/publishe