Use of opioids in the management of oncological pain

An updated literature review was made using the resources available in Infomed, specifically Ebsco and PubMed, and from MEDLINE database with the aim of describing updated aspects of oncological pain management using opioid medications. Of the total bibliography consulted, 35 where cited in the work, using qualitative research methods. It was concluded that opioids, especially morphine, are the drugs of choice in these cases. Most of the literature consulted refers that the management of cancer pain is inadequate due to insufficient knowledge of health professionals about their evaluation and strategies to reduce tolerance, physical dependence, opioid addiction influences the negative attitudes of patients, and family members and the inconveniences related to regulations for the control of these drugs and their adverse effects.Key words: morphine; cancer pain; analgesics; opioid; opioid rotatio

Adverse reactions to non-opioid analgesics notified in Las Tunas, 2017 though the first semester of 2019

Background: non-opioid analgesics are the mostly used drugs for pain relief and inflammation worldwide. However, this benefit is closely associated with adverse reactions.Objective: to characterize the adverse reactions to non-opioid analgesics registered at the database of pharmacovigilance of the province of Las Tunas, from 2017 to the first semester of 2019.Methods: a cross-sectional, descriptive, observational study was carried out at the place and during the period herein declared. The university consisted of the 1711 registers of the main adverse reactions conducted in the study period and the sample included 180 corresponding to non-opioid analgesics. Descriptive statistics was used for the analysis of data.Results: the highest number of registers were related to the female sex with 116 reports (64,4 %) and the 41 to 60 age group with 68 (37,8 %). The adverse reactions that predominated were the frequent ones, 68 registers (37,8 %); according to severity there was a higher notification of the mild ones with 98 reports (54,4 %) and according to causality the probable ones prevailed with 137 registers (76,7 %). The mostly affected organ system was the skin, 84 registers (46,7 %), being cutaneous eruption, with 18 registers (10 %), the most registered one within the system and in general among all reactions. The drug with most registers of adverse reactions was metamizole, 56 registers (31,1 %).Conclusions: the study could characterize the notifications of adverse reactions to non-opioid analgesics in Las Tunas.</p