Leishmaniose en Equateur : 1. Incidence de la leishmaniose tégumentaire sur la façade pacifique

Une enquête porte à porte sur 961 personnes dans deux stations de la côte Pacifique de l'Equateur a permis d'évaluer l'incidence et la prévalence de la leishmaniose tégumentaire à #Leishmania panamensis$, et de noter ses manifestations cliniques. Dans les collines subandines, à Paraiso Escondido, la prévalence de cas actifs était de 4,8 %; dans les collines de la cordillère littorale, elle était de 3,6 %, et dans les deux cas il n'y avait pas de différence significative entre les sexes. L'incidence de nouveaux cas en 1991 était forte, 147 °/oo à Paraiso Escondido, et 106 °/oo à La Tablada. La prévalence cumulée atteignait 66 % à Paraiso Escondido, et 47 % à La Tablada. 62 % des patients des deux stations présentaient une seule lésion ou cicatrice. Autochtones et migrants se contaminent dans leurs cinq premières années d'existence en zone d'endémie. Néammoins, l'incidence reste élevée dans toutes les classes d'âge en raison du grand nombre de migrants (50 %). Les questionnaires ont révélé une contamination en saison sèche, de juillet jusqu'à la fin d'année. La moustiquaire était utilisée comme protection contre les phlébotomes. Ces caractéristiques clinico-épidémiologiques étaient corroborées par celles, obtenues en détection passive, à l'Hôpital A. Egas de Santo Domingo. La contamination de jeunes enfants et d'adultes des deux sexes, les lésions à la face, suggèrent une transmission domiciliaire. (Résumé d'auteur

The secondary eclipses of WASP-19b as seen by the ASTEP 400 telescope from Antarctica

The ASTEP (Antarctica Search for Transiting ExoPlanets) program was originally aimed at probing the quality of the Dome C, Antarctica for the discovery and characterization of exoplanets by photometry. In the first year of operation of the 40 cm ASTEP 400 telescope (austral winter 2010), we targeted the known transiting planet WASP-19b in order to try to detect its secondary transits in the visible. This is made possible by the excellent sub-millimagnitude precision of the binned data. The WASP-19 system was observed during 24 nights in May 2010. The photometric variability level due to starspots is about 1.8% (peak-to-peak), in line with the SuperWASP data from 2007 (1.4%) and larger than in 2008 (0.07%). We find a rotation period of WASP-19 of 10.7 +/- 0.5 days, in agreement with the SuperWASP determination of 10.5 +/- 0.2 days. Theoretical models show that this can only be explained if tidal dissipation in the star is weak, i.e. the tidal dissipation factor Q'star > 3.10^7. Separately, we find evidence for a secondary eclipse of depth 390 +/- 190 ppm with a 2.0 sigma significance, a phase consistent with a circular orbit and a 3% false positive probability. Given the wavelength range of the observations (420 to 950 nm), the secondary transit depth translates into a day side brightness temperature of 2690(-220/+150) K, in line with measurements in the z' and K bands. The day side emission observed in the visible could be due either to thermal emission of an extremely hot day side with very little redistribution of heat to the night side, or to direct reflection of stellar light with a maximum geometrical albedo Ag=0.27 +/- 0.13. We also report a low-frequency oscillation well in phase at the planet orbital period, but with a lower-limit amplitude that could not be attributed to the planet phase alone, and possibly contaminated with residual lightcurve trends.Comment: Accepted for publication in Astronomy and Astrophysics, 13 pages, 13 figure

Hepatitis B virus infection among medical aste handlers in Addis Ababa, Ethiopia

<p>Abstract</p> <p>Background</p> <p>Healthcare wastes contain a wide range of microorganisms among which hepatitis B virus (HBV) are the most significant pathogens. No data about the prevalence of HBV among medical waste handlers is available in Addis Ababa, Ethiopia. Therefore; this study was conducted to describe the prevalence of HBV infection among medical waste handlers in Government hospitals of Addis Ababa, Ethiopia.</p> <p>Findings</p> <p>A cross sectional study was conducted among 252 medical and non-medical waste handlers working in three Government hospitals of Addis Ababa between May to July, 2010. Predesigned and tested questionnaire was used to collect soiociodemographic information. Blood sample was taken from 252 waste handlers and serum was tested for Hepatitis B surface antigen (HBsAg) and anti-Hepatitis core antigen (anti-HBcAg) using Enzyme Linked Immuno Sorbent Assay.</p> <p>Of the 126 Medical Waste Handlers and 126 Non Medical Waste Handler, HBsAg was detected in 8 (6.3%) and 1 (0.8%), and anti-HBcAg in 60 (47.6%) and 40 (31.7%), respectively. Significant differences were observed in the detection rates of HBsAg (OR: 8, 95% CI: 1.02, 63.02; <it>p </it>= 0.01), Anti-HB c Ag (OR: 1.5, 95% CI: 1.1, 2.1; <it>p </it>= 0.01) and either markers (OR: 1.7, 95% CI: 1.2, 2.2; <it>p </it>= 0.001) in medical waste handlers compared to non medical waste handlers. 19.8% were trained to handle medical waste and none was immunized against HBV.</p> <p>Conclusion</p> <p>This study shows a high prevalence of HBV infection in medical waste handlers compared to non medical waste handlers. Lack of training on how to handle medical waste among medical waste handlers was high.</p

The epidemiology of suicide and attempted suicide in Dutch general practice 1983–2003

BACKGROUND: Many patients attempting or committing suicide consult their general practitioner (GP) in the preceding period, indicating that GPs might play an important role in prevention. The aim of the present study was to analyse the epidemiology of suicidal behaviour in Dutch General Practice in order to find possible clues for prevention. METHOD: Description of trends in suicide and suicide attempts occurring from 1983–2003 in the Dutch General Practice Sentinel Network, representing 1% of the Dutch population. The data were analysed with regard to: 1) suicidal behaviour trends and their association with household situation; 2) presence of depression, treatment of depression and referral rate by GPs; 3) contact with GP before suicide or suicide attempt and discussion of suicidal ideation. RESULTS: Between 1983 and 2003 the annual number of suicide and suicide attempts decreased by 50%. Sixty percent of the patients who committed or attempted suicide were diagnosed as depressed, of whom 91% were treated by their GP with an antidepressant. Living alone was a risk factor for suicide (odds ratio 1.99; 95% CI 1.50 to 2.64), whereas living in a household of 3 or more persons was a relative risk for a suicide attempt (odds ratio 1.81; 95% CI 1.34 to 2.46). Referral to a psychiatrist or other mental health professionals occurred in 65% of the cases. GPs recalled having discussed suicidal ideation in only 7% of the cases, and in retrospect estimated that they had foreseen suicide or suicide attempts in 31% and 22% of the cases, respectively, if there had been contact in the preceding month. CONCLUSION: With regard to the prescription of antidepressants and referral of suicidal patients to a psychiatrist, Dutch GPs fulfil their role as gatekeeper satisfactorily. However, since few patients discuss their suicidal ideation with their GP, there is room for improvement. GPs should take the lead to make this subject debatable. It may improve early recognition of depressed patients at risk and accelerate their referral to mental health professionals