A Preliminary Investigation of Acculturative Stress and Diurnal Cortisol Among Latina Women

The interplay between biological and cultural factors has remained understudied among ethnic minority groups, including Latinos. To the best of our knowledge, minimal to no research has examined the relationship between acculturative stressors and diurnal cortisol among Latina women. This initial exploratory study sought to examine the relationship between cortisol and acculturative stress. Among a small sample of adult Latina women, salivary cortisol was collected at 3 time points (waking, 30 min postwaking, and bedtime) to assess the cortisol awakening response (CAR) and diurnal cortisol response. Information regarding acculturative stress and acculturation was also collected. The major results showed that high levels of acculturative stress were associated with a blunted CAR and a flatter diurnal cortisol response when compared to low levels of acculturative stress. These preliminary findings highlight the potential role of cultural stressors in contributing to the biological stress response

Isolated Trapezoid Fracture in a Boxer

BACKGROUND Trapezoid fractures are very uncommon, accounting for less than 1% of all wrist fractures. Isolated fractures of this bone are even more rare, with just a few reports in the literature. The trapezoid bone has a very stable position within the wrist, forming a relatively immobile joint with the second metacarpal base distally. It is also connected by very strong ligaments to the trapezium, capitate and, scaphoid. Trapezoid fractures occur when a strong bending or axial force is applied to the second metacarpal base. CASE REPORT We present a clinical case of an isolated, non-displaced, trapezoid fracture in a young white male, which was treated with cast immobilization for 4 weeks and physical therapy. Complete functional recovery was achieved 3 months after the injury, without any pain or tenderness. CONCLUSIONS Fractures of the trapezoid bone usually have a good clinical outcome. Nonetheless, we need to be very suspicious about this diagnosis since radiography is apparently normal in almost all such cases and clinical examination results may not be entirely clear.info:eu-repo/semantics/publishedVersio

Mathematical Models for Estimating the Risk of vCJD Transmission

We present two different simple models for vCJD transmission by blood transfusion. Both models indicate that transfusions alone are unlikely to cause more than a few infections, unless the number of primary cases increases. To improve our models, future work should pursue data collection, empirical estimation of the model parameters, and examination of the underlying assumptions of our frameworks. Further improvements could also include examining susceptibility to vCJD infection by age group and iatrogenic infections introduced through surgical instruments. Regarding the latter, it may be worthwhile to conduct experiments to quantify the transmission of prions from an infected surgical instrument after repeated sterilization procedures

Junctional sarcoplasmic reticulum motility in adult mouse ventricular myocytes.

Excitation-contraction (EC) coupling is the coordinated process by which an action potential triggers cardiac myocyte contraction. EC coupling is initiated in dyads where the junctional sarcoplasmic reticulum (jSR) is in tight proximity to the sarcolemma of cardiac myocytes. Existing models of EC coupling critically depend on dyad stability to ensure the fidelity and strength of EC coupling, where even small variations in ryanodine receptor channel and voltage-gated calcium channel-α 1.2 subunit separation dramatically alter EC coupling. However, dyadic motility has never been studied. Here, we developed a novel strategy to track specific jSR units in dissociated adult ventricular myocytes using photoactivatable fluorescent proteins. We found that the jSR is not static. Instead, we observed dynamic formation and dissolution of multiple dyadic junctions regulated by the microtubule-associated molecular motors kinesin-1 and dynein. Our data support a model where reproducibility of EC coupling results from the activation of a temporally averaged number of SR Ca2+ release units forming and dissolving SR-sarcolemmal junctions. These findings challenge the long-held view that the jSR is an immobile structure and provide insights into the mechanisms underlying its motility

The UNAM-KIAS Catalog of Isolated Galaxies

A new catalog of isolated galaxies from The Sloan Digital Sky Survey (DR5) is presented. 1520 isolated galaxies were found in 1.4 steradians of sky. The selection criteria in this so called UNAM-KIAS catalog was implemented from a variation on the criteria developed by Karachentseva 1973 including full redshift information. Through an image processing pipeline that takes advantage from the high resolution (~ 0.4 ''/pix) and high dynamic range of the SDSS images, a uniform g band morphological classification for all these galaxies is presented. We identify 80% (SaSm) spirals (50% later than Sbc types) on one hand, and a scarce population of early-type E(6.5%) and S0(8%) galaxies amounting to 14.5% on the other hand. This magnitude-limited catalog is ~ 80% complete at 16.5, 15.6, 15.0, 14.6 and 14.4 magnitudes in the ugriz bands respectively. Some representative physical properties including SDSS magnitudes and color distributions, color-color diagrams, absolute magnitude-color, and concentration-color diagrams as a function of morphological type are presented. The UNAM-KIAS Morphological Atlas is also released along with this paper. For each galaxy of type later than Sa, a mosaic is presented that includes: (1) a g-band logarithmic image, (2) a g band filtered-enhanced image where a Gaussian kernel of various sizes was applied and (3) an RGB color image from the SDSS database. For E/S0/Sa galaxies, in addition to the images in (1), (2) and (3), plots of r band surface brightness and geometric profiles (ellipticity, Position Angle PA and A4/B4 coefficients of the Fourier series expansions of deviations of a pure ellipse) are provided...Comment: 40 pages, 17 figures and 3 table