Quality in subtitling: theory and professional reality

The issue of quality is of great importance in translation studies and, although some studies have been conducted in the field of subtitling, most discussions have been limited to aspects such as how to become a good subtitler and how to produce quality subtitles. Little research has been carried out to investigate other potential factors that may influence the quality of subtitling output in practice. In recent years, some subtitling courses at postgraduate level have attempted to bridge the gap between academia and industry, not only by incorporating the teaching of linguistic and technical skills into the curriculum but also by informing students about ethics, working conditions, market competition, and other relevant professional issues. This instruction is intended to prepare them for promising careers in the subtitling industry, where a progressively deteriorating trend has been observed by some professional subtitlers. The main aim and objective of this study is to explore both theoretical and practical aspects of subtitling quality. The study aspires to call attention to the factors influencing the quality of subtitles and also to provide suggestions to improve the state of affairs within the subtitling industry in terms of quality. In order to examine the potential factors that influence the perception of subtitling quality, particularly in the professional context, two rounds of online surveys were conducted to establish the working conditions of subtitlers. Despite the fact that the participants in the first survey were based in thirty-nine different countries, the data collected is more representative of the situation in Europe, where subtitling is a relatively mature industry compared to other parts of the world. The second survey targeted subtitlers working with the Chinese language in an attempt to study the burgeoning Chinese audiovisual market. This thesis provides a systematic analysis of the numerous parameters that have an impact on the quality of subtitling, both in theory and in professional reality, and offers a detailed insight into the working environment of subtitlers. At the same time, it endeavours to draw attention to the need to ensure decent working conditions in the industry. The general findings are discussed in terms of their implications for the development of the profession as well as for subtitler training and education.Open Acces

Community Functioning and Cognitive Performance in Schizophrenia: The Nature of the Relationship

Although cognition is one of the most important predictors of community functioning in schizophrenia, little is known about the causes of this relationship. This study is the first to our knowledge to examine the extent to which this correlation is genetically and/or environmentally mediated and its degree of specificity to schizophrenia. Six hundred and thirty-six participants from 43 multigenerational families with at least two schizophrenia relatives and 135 unrelated controls underwent diagnostic interview and functioning assessment along with the Penn Computerized Neurocognitive Battery, Trail Making Test and California Verbal Learning Test. Exploratory factor analyses yielded one general cognition factor and one functioning factor while a social cognition factor was comprised of the average of two tasks. SOLAR (Sequential Oligogenic Linkage Analysis Routines) (Almasy & Blangero, 1998) was used to conduct family-based analyses quantifying genetic and environmental effects on the cognition-functioning correlation. As expected, among the 103 relatives with schizophrenia, there was considerable variation in functioning and cognitive performance and a significant correlation between the two (Rp=0.335, p=0.005). Shared genetic effects were significant contributors to this relationship (Rg=0.956, p<0.001) whereas idiosyncratic experiences were not. In contrast, shared genetic effects were not significant among relatives with major depression, substance abuse or no psychopathology. Furthermore, functioning in schizophrenia was not significantly predicted by cognition in relatives from other diagnostic groups. Across all analyses, the contributions of social cognition to functioning were similar to and fully accounted for by general cognition. The cognition-functioning correlation in schizophrenia is largely attributable to genetic factors specific to the disorder that also encompass genetic effects on the association between social cognition and functioning. These findings provide a foundation from which heritable factors contributing to functioning in schizophrenia can be differentiated from those contributing to functioning in psychiatric disorders in general, which suggest that investigations of specific genetic variants contributing to this association are warranted

Study on the Correlation between Objective Evaluations and Subjective Speech Quality and Intelligibility

Subjective tests are the gold standard for evaluating speech quality and intelligibility, but they are time-consuming and expensive. Thus, objective measures that align with human perceptions are crucial. This study evaluates the correlation between commonly used objective measures and subjective speech quality and intelligibility using a Chinese speech dataset. Moreover, new objective measures are proposed combining current objective measures using deep learning techniques to predict subjective quality and intelligibility. The proposed deep learning model reduces the amount of training data without significantly impacting prediction performance. We interpret the deep learning model to understand how objective measures reflect subjective quality and intelligibility. We also explore the impact of including subjective speech quality ratings on speech intelligibility prediction. Our findings offer valuable insights into the relationship between objective measures and human perceptions

Effect of Supplementation of Tanshinone IIA and Sodium Tanshinone IIA Sulfonate on the Anticancer Effect of Epirubicin: An In Vitro Study

Tanshinone IIA (Tan IIA) and sodium tanshinone IIA sulfonate (STS) were found to have protective effects on cardiomyocyte against adriamycin-induced damage and may be used clinically. It is unclear whether the supplementation of STS or Tan IIA would affect the anticancer activity of anthracycline. To evaluate the effect of Tan IIA or STS on the anticancer of epirubicin, the cell viability, apoptosis, Akt expression, and uptake of epirubicin after supplementation of Tan IIA or STS in the epirubicin-treated BT-20 cells were measured and compared. Tan IIA inhibited BT-20 cell growth and induced apoptosis in a time- and dose-dependent manner. When Tan IIA was used with epirubicin, an increase of BT-20 cells apoptosis was accompanied by the decreasing phosphorylation of Akt. STS had no effect on the cell viability of BT-20 cells. However, when used with epirubicin, STS decreased the epirubicin-induced cytotoxicity and apoptosis in BT-20 cells. The antagonistic effect of STS on epirubicin-induced cytotoxicity in BT-20 cells occurred concomitantly with the reduced epirubicin uptake and the increased phosphorylation of Akt. STS decreased the uptake of epirubicin in BT-20 cells and blocked epirubicin-induced apoptosis through activation of Akt

Ginsenoside-Rg1 Protects the Liver against Exhaustive Exercise-Induced Oxidative Stress in Rats

Despite regular exercise benefits, acute exhaustive exercise elicits oxidative damage in liver. The present study determined the hepatoprotective properties of ginsenoside-Rg1 against exhaustive exercise-induced oxidative stress in rats. Forty rats were assigned into vehicle and ginsenoside-Rg1 groups (0.1 mg/kg bodyweight). After 10-week treatment, ten rats from each group performed exhaustive swimming. Estimated oxidative damage markers, including thiobarbituric acid reactive substance (TBARS) (67%) and protein carbonyls (56%), were significantly (P < 0.01) elevated after exhaustive exercise but alleviated in ginsenoside-Rg1 pretreated rats. Furthermore, exhaustive exercise drastically decreased glutathione (GSH) content (∼79%) with concurrent decreased superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities. However, these changes were attenuated in Rg1 group. Additionally, increased xanthine oxidase (XO) activity and nitric oxide (NO) levels after exercise were also inhibited by Rg1 pretreatment. For the first time, our findings provide strong evidence that ginsenoside-Rg1 can protect the liver against exhaustive exercise-induced oxidative damage