17 research outputs found
Anaemia in the Premature Infant and Red Blood Cell Transfusion: New Approaches to an Age-Old Problem
The relationship between cardiac output, cerebral electrical activity, cerebral fractional oxygen extraction and peripheral blood flow in premature newborn infants
Respiratory support for premature neonates in the delivery room: effects on cardiovascular function and the development of brain injury
Relationship between blood pressure, cerebral electrical activity, cerebral fractional oxygen extraction, and peripheral blood flow in very low birth weight newborn infants
Perioperative Cerebral Oxygenation Metabolism in Neonates with Hypoplastic Left Heart Syndrome or Transposition of the Great Arteries
Relationship Between Blood Pressure, Cerebral Electrical Activity, Cerebral Fractional Oxygen Extraction, and Peripheral Blood Flow in Very Low Birth Weight Newborn Infants
The Relationship between Cardiac Output, Cerebral Electrical Activity, Cerebral Fractional Oxygen Extraction and Peripheral Blood Flow in Premature Newborn Infants
In preterm infants, ascending intrauterine infection is associated with lower cerebral tissue oxygen saturation and higher oxygen extraction
BACKGROUND: Placental lesions are associated with neurological morbidity but the mechanism leading to morbidity is unclear. To provide insight into such a possible mechanism, we determined whether placental lesions were associated with regional cerebral tissue oxygen saturation (r(c)SO(2)) and fractional tissue oxygen extraction (FTOE) in preterm infants during their first 5 d after birth. We hypothesized that as a result of cerebral hypoperfusion, rcSO2 would be lower and FTOE would be higher. METHOD: In a prospective, observational study of 42 preterm infants (gestational age RESULTS: Only three placentas showed no pathology. Ascending intrauterine infection (AlUI) (n = 16) was associated with lower r(c)SO(2) and higher FTOE values on days 2, 3, and 4 (P CONCLUSION: AlUI is associated with lower r(c)SO(2), and higher FTOE shortly after birth. The effect it has on cerebral oxygenation might be the mechanism leading to neurodevelopmental problems