Quantitative measurement of portal blood flow by magnetic resonance phase contrast: comparative study of flow phantom and Doppler ultrasound in vivo.

A non-invasive method for measuring portal blood flow by magnetic resonance (MR) phase contrast was evaluated in a flow phantom and 20 healthy volunteers. In a flow phantom study, the flow volumes and mean flow velocities measured by MR phase contrast showed close correlations with those measured by electromagnetic flowmetry. In 20 healthy volunteers, the cross-sectional areas, flow volumes and mean flow velocities measured by MR phase contrast correlated well with those measured by the Doppler ultrasound method. Portal blood flow averaged during the imaging time could be measured under natural breathing conditions by using a large number of acquisitions without the limitations imposed on the Doppler ultrasound method. MR phase contrast is considered to be useful for the non-invasive measurement of portal blood flow.</p

The Effects of Intravenous Feeding on Tumor Growth : An Autoradiographic Analysis

Effects of parenteral nutrition on tumor growth were examined by using autoradiographic procedures. Growth rate of the Sato\u27s lung cancer inplanted subcutaneously in the back of the rats of malnourished group was significantly lower (2.68±0.82, p<0.001) than that of intravenously alimented group and orally fed group (5.19± 1.50, 5.72±1.69, respectively). Both mitotic index and labeling index of the tumors from malnourished rats were significantly lower compared with orally fed rats, and this tendency was remarkable in the central region of tumor. Labeling index of parenterally fed group was significantly higher than that of orally fed group. Even in the central region of tumor in this group, labeling intensity was not decreased compared with subcapsular region. Percentage of labeled mitoses of the tumors from the intravenously fed animals was lower than orally fed one\u27s. Based on these findings, it is anticipated that parenteral nutrition may increase or maintain the tumor cells being mobilized in the tumor proliferation phase. This point seems to be useful for the anti-tumor chemotherapy

Resection of Hepatic Metastasis from Colorectal Cancer : Survival, Factors Influencing Prognosis, and Follow-up

The purpose of this retrospective study was to analyze the surgical results of hepatic resection in our patients with colorectal hepatic metastasis. During a 26-year period, 223 patients among 1,484 patients with colorectal cancer suffered liver metastasis. In 44 curatively resected patients, the one-, three- and five-year cumulative survival rates were 85.9%, 44.9% and 23.0%, respectively. The prognostic importance of seven factors was evaluated. Synchronous or metachronous resection, the type of liver resection, and histologic differentiation did not influence the prognosis, whereas the number and size of metastases, and lymph node involvement did significantly affect prognosis as single factors. The mean diameter of metastatic lesions in the liver was 2.5 cm in the synchronous group and 4.5 cm in the metachronous group, the difference being significant (p = 0.0005). The presence of tumors with large diameters in the metachronous group might mean our failure of early detection of the recurrence of hepatic metastases. It is necessary to make steady efforts such as introducing regular follow-up imaging of colorectal cancer. The median interval between the primary operation and liver metastasis resection was 15.7 months in the lymph node involvement group and 37.7 months in the no lymph node involvement group. In 19 patients among 21 metachronously resected patients, the hepatic resection was done within three years. In conclusion, it was considered that hepatectomy could be done safely, that detection of an earlier lesion could improve the surgical results, and that follow-up for liver metastasis should be done intensively between 12 and 36 months after colorectal cancer surgery

Cryosurgical Hemorrhoidectomy: Technique and Method

The key to gain successful results with cryosurgical hemorrhoidectomy is based on the prevention of prolapse of the edematous tissue after freezing. To prevent the edema, it is important to pull out the hemorrhoid as much as possible during freezing, to freeze only on the rectal side of the anal verge, to avoid freezing the anal verge, and to freeze the hemorrhoids in two or three separate stages when they are large such as the fourth-degree. The anal discomfort and discharge in these patients are related to prolapse of frozen tissue. Cryosurgery is an effective method of treatment for hemorrhoids if care is taken to use the proper techniques

A Cystic Lymphangioma of the Colon Seen in a Patient with Early Gastric Cancer

Lymphangiomas are very rare benign neoplasms of the gastrointestinal tract. A case of cystic lymphangioma in the hepatic flexure of the colon seen in patient with early gastric cancer is reported and the literature is reviewed

Lymphangioma of the Small Intestine : A Case Report

Lymphangiomas of the small intestine are rare tumors arising from masses of dilated lymphatic vessels in the submucosa. There are 11 cases of lymphangioma of the small intestine in the Japanese literature. We report a case of lymphangioma of the jejunum seen in a 76-year-old female and discuss with clinical feature

宿便性結腸穿孔の1例

宿便成結腸穿孔は比較的稀な疾患である.今回我々は本症例の1例を経験した.症例は66歳,女性.腹痛を主訴に来院した.来院時腹部所見は板上硬で左下腹部に強度の圧通を認め,腸音は減弱していた.単純X線写真にて両側横隔膜下に遊離ガス像を認め,下部消化器管穿孔,汎発生腹膜炎の診断にて緊急手術を施行した.手術所見では下行結腸から直腸内に硬便が充満していた.S字結腸に穿孔部を認め,その近傍に腸管内から脱出した便塊を認めた.手術はハルトマン手術を施行した.切除標本では穿孔部は楕円形であり,手術所見,病理組織学的所見とあわせて宿便性結腸穿孔と診断した.術後は経過良好であった.手術から12ヶ月後,人工肛門閉鎖,下行結腸直腸吻合術を施行した.Stercoral colonic perforation is a relatively rare entity. This paper presents such a case in a 66-year-old woman. The patient was visited the hospital because of abdominal pain. Her abdomen was board-like, there was severe tenderness in the left lower quadrant, and bowel sounds were hypoactive. The abdominal x-ray film showed free air beneath the bilateral diaphragm. Lower gastrointestinal perforation and generalized peritonitis were diagnosed and an emergency operation performed. At laparotomy, the intestine from the descending colon to the rectum was filled with hard stool. A perforation was present in the sigmoid colon and, in the vicinity of the perforation, the stool mass had fallen away from the inside of the intestine. A Hartmann procedure was employed. On the resected material, the perforation was oval in shape. From operative and histopathological findings, a definite diagnosis of stercoral colonic perforation was made. The postoperative course was uneventiful. Twelve months after the operation, closure of an artificial anus and an anastomosis between the descending colon and the rectum were performed