135 research outputs found
Construction of quasi-cyclic self-dual codes
There is a one-to-one correspondence between -quasi-cyclic codes over a
finite field and linear codes over a ring . Using this correspondence, we prove that every
-quasi-cyclic self-dual code of length over a finite field
can be obtained by the {\it building-up} construction, provided
that char or , is a prime , and
is a primitive element of . We determine possible weight
enumerators of a binary -quasi-cyclic self-dual code of length
(with a prime) in terms of divisibility by . We improve the result of
[3] by constructing new binary cubic (i.e., -quasi-cyclic codes of length
) optimal self-dual codes of lengths (Type I), 54 and
66. We also find quasi-cyclic optimal self-dual codes of lengths 40, 50, and
60. When , we obtain a new 8-quasi-cyclic self-dual code
over and a new 6-quasi-cyclic self-dual code over
. When , we find a new 4-quasi-cyclic self-dual
code over and a new 6-quasi-cyclic self-dual code
over .Comment: 25 pages, 2 tables; Finite Fields and Their Applications, 201
DESIGNING COST-EFFECTIVE COARSE-GRAINED RECONFIGURABLE ARCHITECTURE
Application-specific optimization of embedded systems becomes inevitable to satisfy the
market demand for designers to meet tighter constraints on cost, performance and power.
On the other hand, the flexibility of a system is also important to accommodate the short
time-to-market requirements for embedded systems. To compromise these incompatible
demands, coarse-grained reconfigurable architecture (CGRA) has emerged as a suitable
solution. A typical CGRA requires many processing elements (PEs) and a configuration
cache for reconfiguration of its PE array. However, such a structure consumes significant
area and power. Therefore, designing cost-effective CGRA has been a serious concern
for reliability of CGRA-based embedded systems.
As an effort to provide such cost-effective design, the first half of this work
focuses on reducing power in the configuration cache. For power saving in the configuration
cache, a low power reconfiguration technique is presented based on reusable context
pipelining achieved by merging the concept of context reuse into context pipelining.
In addition, we propose dynamic context compression capable of supporting only required
bits of the context words set to enable and the redundant bits set to disable. Finally, we provide dynamic context management capable of reducing reduce power consumption
in configuration cache by controlling a read/write operation of the redundant
context words
In the second part of this dissertation, we focus on designing a cost-effective PE array
to reduce area and power. For area and power saving in a PE array, we devise a costeffective
array fabric addresses novel rearrangement of processing elements and their
interconnection designs to reduce area and power consumption. In addition, hierarchical
reconfigurable computing arrays are proposed consisting of two reconfigurable computing
blocks with two types of communication structure together. The two computing
blocks have shared critical resources and such a sharing structure provides efficient
communication interface between them with reducing overall area.
Based on the proposed design approaches, a CGRA combining the multiple design
schemes is shown to verify the synergy effect of the integrated approach. Experimental
results show that the integrated approach reduces area by 23.07% and power by up to
72% when compared with the conventional CGRA
BubbleML: A Multi-Physics Dataset and Benchmarks for Machine Learning
In the field of phase change phenomena, the lack of accessible and diverse
datasets suitable for machine learning (ML) training poses a significant
challenge. Existing experimental datasets are often restricted, with limited
availability and sparse ground truth data, impeding our understanding of this
complex multiphysics phenomena. To bridge this gap, we present the BubbleML
Dataset
\footnote{\label{git_dataset}\url{https://github.com/HPCForge/BubbleML}} which
leverages physics-driven simulations to provide accurate ground truth
information for various boiling scenarios, encompassing nucleate pool boiling,
flow boiling, and sub-cooled boiling. This extensive dataset covers a wide
range of parameters, including varying gravity conditions, flow rates,
sub-cooling levels, and wall superheat, comprising 79 simulations. BubbleML is
validated against experimental observations and trends, establishing it as an
invaluable resource for ML research. Furthermore, we showcase its potential to
facilitate exploration of diverse downstream tasks by introducing two
benchmarks: (a) optical flow analysis to capture bubble dynamics, and (b)
operator networks for learning temperature dynamics. The BubbleML dataset and
its benchmarks serve as a catalyst for advancements in ML-driven research on
multiphysics phase change phenomena, enabling the development and comparison of
state-of-the-art techniques and models.Comment: Submitted to Neurips Datasets and Benchmarks Track 202
Flud: a hybrid crowd-algorithm approach for visualizing biological networks
Modern experiments in many disciplines generate large quantities of network
(graph) data. Researchers require aesthetic layouts of these networks that
clearly convey the domain knowledge and meaning. However, the problem remains
challenging due to multiple conflicting aesthetic criteria and complex
domain-specific constraints. In this paper, we present a strategy for
generating visualizations that can help network biologists understand the
protein interactions that underlie processes that take place in the cell.
Specifically, we have developed Flud, an online game with a purpose (GWAP) that
allows humans with no expertise to design biologically meaningful graph layouts
with the help of algorithmically generated suggestions. Further, we propose a
novel hybrid approach for graph layout wherein crowdworkers and a simulated
annealing algorithm build on each other's progress. To showcase the
effectiveness of Flud, we recruited crowd workers on Amazon Mechanical Turk to
lay out complex networks that represent signaling pathways. Our results show
that the proposed hybrid approach outperforms state-of-the-art techniques for
graphs with a large number of feedback loops. We also found that the
algorithmically generated suggestions guided the players when they are stuck
and helped them improve their score. Finally, we discuss broader implications
for mixed-initiative interactions in human computation games.Comment: This manuscript is currently under revie
Favorable prognosis in colorectal cancer patients with co-expression of c-MYC and Γ-catenin
This article is distributed under the terms of the Creative Commons Attribution 4.0
International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and
reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to
the Creative Commons license, and indicate if changes were made.Abstract
Background
The purpose of our research was to determine the prognostic impact and clinicopathological feature of c-MYC and Ξ²-catenin overexpression in colorectal cancer (CRC) patients.
Methods
Using immunohistochemistry (IHC), we measured the c-MYC and Ξ²-catenin expression in 367 consecutive CRC patients retrospectively (cohort 1). Also, c-MYC expression was measured by mRNA in situ hybridization. Moreover, to analyze regional heterogeneity, three sites of CRC including the primary, distant and lymph node metastasis were evaluated in 176 advanced CRC patients (cohort 2).
Results
In cohort 1, c-MYC protein and mRNA overexpression and Γ-catenin nuclear expression were found in 201 (54.8Β %), 241 (65.7Β %) and 221 (60.2Β %) of 367 patients, respectively, each of which was associated with improved prognosis (Pβ=β0.011, Pβ=β0.012 and Pβ=β0.033, respectively). Moreover, co-expression of c-MYC and Γ-catenin was significantly correlated with longer survival by univariate (Pβ=β0.012) and multivariate (Pβ=β0.048) studies. Overexpression of c-MYC protein was associated with mRNA overexpression (Ο, 0.479; Pββ0.05).
Conclusions
Co-expression of c-MYC and Γ-catenin was independently correlated with favorable prognosis in CRC patient. We concluded that the expression of c-MYC and Γ-catenin might be useful predicting indicator of CRC patients prognosis
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