34 - Fraud and Frill: Women and Spiritualism in Victorian America

Spiritualism rose in the United States after the Civil War and was popularized mainly by women. Through spiritualism, women broke free from the restraints of the widely-held separate spheres ideology. I researched five Victorian women and how they utilized their talents to become famous spiritualists. In a poster presentation, I illustrate that these women did not set out to simply defraud grieving families and confuse the world with frivolity, as contemporary skeptics of spirituality contended, but had motives beyond monetary gain. I show that these women used the paranormal to become voices for women who did not have one. The Fox Sisters used table rappings to further religious tolerance. Victoria Woodhull used her popularity as magnetic healer to springboard into presidential politics. Cora Hatch used trances to speak out for abolitionism. Florence Cook worked through physical manifestations to travel the world while exploring her sexual identity. I will conclude why these five women no longer fought back and succumbed to the decline of spiritualism in early twentieth century

Can a simple measure of vigorous physical activity predict future mortality? Results from the OXCHECK study.

BACKGROUND: As epidemiological studies have become more complex, demands for short, easily administered measures of risk factors have increased. This study investigates whether such a measure of physical activity is associated with the risk of death from all causes and death from specific causes. METHODS: A prospective follow-up study of 11,090 men and women, aged 35-64 years, recruited from five UK general practices who responded to a postal questionnaire in 1989. Self-reported frequency of vigorous-intensity physical activity and data on confounding factors were collected at baseline survey. Death notifications up to 31 December 2001 were provided by the Office for National Statistics. The relative risk (and 95% confidence interval) of dying associated with each level of exposure to physical activity was estimated by the hazard ratio in a series of Cox regression models. RESULTS: After >10 years' follow-up there were 825 deaths among the 10 522 subjects with no previous history of angina or myocardial infarction. Participation in vigorous exercise was associated with a significantly lower risk of all-cause mortality. Similar associations were found for ischaemic heart disease and cancer mortality, although the relationships were not significant at the 5% level. CONCLUSIONS: Simple measures of self-reported vigorous physical activity are associated with the risk of future mortality, at least all-cause mortality in a somewhat selected group. Interpretation of the finding should be treated with caution due to the reliance on self-report and the possibility that residual confounding may underlie the associations. Because moderate-intensity physical activity is also beneficial to health, short physical activity questionnaires should include measures of such physical activity in the future

Exploring changes in health visitors' knowledge, confidence and decision-making for women with perinatal mental health difficulties following a brief training package

Rationale and objective: Perinatal Mental Health (PMH) is an issue that spans the spectrum of pregnancy and childbirth and is now acknowledged to be significant on a global level. Health visitors (HVs) are increasingly expected to extend their knowledge and to understand and identify PMH in the antenatal period and across the spectrum from mild/moderate to severe. While training has been shown to enable HVs to identify post-natal depression (PND) effectively and reduce the proportion of women at risk, the mechanisms underpinning this success are unclear. This paper reports on the findings of a mixed methods study aimed at examining the impact of a single half day training session on perinatal mental health problems (PMHP) on HVs knowledge, confidence and empowerment in relation to managing PMH. Methods: Findings from data gathered by Likert Scales and focus group discussions are presented. Results: Training can empower HVs to identify PMHP beyond PND and plays a vital role in promoting confidence. Conclusions: This research highlights the potential that training of this type has on service provision and delivery. In a resource-limited service, the feasibility of a brief training package has demonstrated positive results for health visitors, childbearing women and their families

Let’s Talk: A Study of the Impact of Gendered Racial Socialization on African American Adolescent Girls’ Mental Health

Internalized racial oppression in African American girls is understudied within research. As people of color are victimized by racism, they may internalize it, developing ideas, beliefs, actions and behaviors that support or collude with racism (Bivens, 1995). This internalized racism has its own systemic reality and its own negative consequences in the lives and communities of people of color. Understanding the way negative racial messages influence the mental health of African American adolescent girls allows for the development of intervention and prevention methods to reduce symptomology of depression, anxiety, and stress. In order for African American girls and young women to develop a healthy sense of self, families must prepare them to cope with the realities of experiencing intersecting oppression (i.e., racism and sexism; Edmondson Bell & Nkomo 1998; Lewis et al. 2013). This may occur through an African American-specific process of gendered racial socialization (Brown et al. 2016). While some research has examined the relationship between racial discrimination and race related stress outcomes (Buford, 2009) or internalized racial oppression on ethnic identity and self-efficacy (La Mar, 2018), there are no current studies that have looked at the impact of internalized gendered racial oppression (IGRO) on negative affect of African American adolescent girls or possible ways to moderate this impact. This study identifies a relationship between IGRO and depression, anxiety and stress symptoms while isolating messages of gendered racial pride and empowerment (GRPE) that reduce these symptoms in Black adolescent girls. To test the hypothesis, GRPE socialization moderates the relationship between IGRO socialization and indicators of psychological wellbeing (i.e., depressive, anxiety, and stress symptoms) this study analyzed the responses of 287 Black adolescent girls (MAge = 15.40) who completed questionnaires assessing the study variables of interest as part of a larger parent-teen dyadic study. A series of hierarchical multiple regression analyses were conducted. Models of the main effects of IGRO and GRPE on depression (R 2 = .04), anxiety (R 2 = .04), and stress (R 2 = .04) were significant (all ps \u3c .001), suggesting these variables accounted for significant variance in the mental health symptoms. For depression, increases in both IGRO (b=.83, p \u3c .001) and GRPE (b=.20, p \u3c .05) were associated with increases in reported depression symptoms. However, examination of the interaction (b=-.16, p \u3c .01) via simple slopes suggested that the Black girls reported higher levels of GRPE, the negative impact of IGRO on depressive symptoms was attenuated. Indeed, at the highest levels of GRPE, the effect of IGRO on depressive symptoms was reduced to non-significance. Similar patterns emerged for teen anxiety and stress, with increased IGRO associated with increasing symptom endorsement and increasing GRPE attenuating this effect. These findings suggest that it is particularly important for African-American youth to receive messages conveying pride and empowerment on being a black girl to aid in reducing the mental health symptoms associated with IGRO. By identifying key messages of gendered racial socialization, this study has the potential to educate parents and teachers on the impact of their messages on children’s mental health. Implications and future directions regarding gendered racial socialization of Black teenaged girls are discussed.https://scholarscompass.vcu.edu/gradposters/1053/thumbnail.jp

DNA repair in the trinucleotide repeat disorders

Background Inherited diseases caused by unstable repeated DNA sequences are rare, but together represent a substantial cause of morbidity. Trinucleotide repeat disorders are severe, usually life-shortening, neurological disorders caused by nucleotide expansions, and most have no disease-modifying treatments. Longer repeat expansions are associated with genetic anticipation (ie, earlier disease onset in successive generations), although the differences in age at onset are not entirely accounted for by repeat length. Such phenotypic variation within disorders implies the existence of additional modifying factors in pathways that can potentially be modulated to treat disease. Recent developments A genome-wide association study detected genetic modifiers of age at onset in Huntington's disease. Similar findings were seen in the spinocerebellar ataxias, indicating an association between DNA damage-response and repair pathways and the age at onset of disease. These studies also suggest that a common genetic mechanism modulates age at onset across polyglutamine diseases and could extend to other repeat expansion disorders. Genetic defects in DNA repair underlie other neurodegenerative disorders (eg, ataxia-telangiectasia), and DNA double-strand breaks are crucial to the modulation of early gene expression, which provides a mechanistic link between DNA repair and neurodegeneration. Mismatch and base-excision repair are important in the somatic expansion of repeated sequences in mouse models of trinucleotide repeat disorders, and somatic expansion of the expanded CAG tract in HTT correlates with age at onset of Huntington's disease and other trinucleotide repeat disorders. Where next? To understand the common genetic architecture of trinucleotide repeat disorders and any further genetic susceptibilities in individual disorders, genetic analysis with increased numbers of variants and sample sizes is needed, followed by sequencing approaches to define the phenotype-modifying variants. The findings must then be translated into cell biology analyses to elucidate the mechanisms through which the genetic variants operate. Genes that have roles in the DNA damage response could underpin a common DNA repeat-based mechanism and provide new therapeutic targets (and hence therapeutics) in multiple trinucleotide repeat disorders