Gender Classification by Speech Analysis

-Gender classification is widely used in automatic speech recognition systems to recognize a speaker speaking continuously in any language. This work aims at analysing speech signals based on some parameters so as to predict the gender of the speaker. This paper comprises of male and female voice samples which were collected to form a database. Parameters such as mean, variance and standard deviation were determined to help in classifying the gender of the speaker

Haematophysiological Study of Transfusion Dependent Beta-thalassaemia Patients in a Tertiary Care Hospital of Odisha, India

Introduction: The Transfusion Dependent Beta-thalassaemia (TDT) is an autosomal recessive disorder that affects the red blood cells, both in the decreased as well as absence in production of Adult Haemoglobin (HbA) and characterised by severe anaemia, splenomegaly and bone deformities and require lifelong transfusion therapy, iron chelation and/ or bone marrow transplantation for successful control. Aim: To evaluate the haematophysiological status of various TDT patients. Materials and Methods: This is a cross-sectional study conducted in the Hematology Department of SCB Medical College and Hospital Cuttack, Odisha, India. The study was done in the duration of 10 months, from April 2021 to January 2022. The blood samples were collected from 62 diagnosed cases of Beta-thalassaemia. Haematophysiological parameters were studied by asking research questionnaire developed for this purpose and analysing various clinical complaints and laboratory data. The haemoglobin variants were analysed by fully automated capillary zone electrophoresis to confirm the diagnosis of homozygous state of Beta-thalassaemia by decreased or absence of globin chain synthesis (HbA2) of the haemoglobin component. The data was anlysed using Statistical Package for Social Sciences (SPSS) version 19. Results: In the present study majority of the patients 39 (62.9%) were below the age of 10 years. The clinical examination showed anaemia in all the patients with haepatomegaly and splenomegaly in 51 (82.25%) and 57 (91.93%) cases respectively. The mean haemoglobin was markedly decreased to 5.98±1.69 ranged from 3 gm% to 10 gm% followed by Foetal Haemoglobin (HbF) was raised up to 78.39±26.73% (normal absent to 0.02%) and adult haemoglobin (HbA2) was increased up to 8.00±5.72 (normal 95% to 98%). Conclusion: TDT is one of the commonest haemoglobinopathy causing major health problem. Common sign and symptoms includes low-grade fever, severe anaemia and haepatosplenomegaly. The Present study helped the families having TDT beta thalassaemia for early detection and avail the facilities given by Government of Odisha

Hepatorenal Toxicity of Inorganic Arsenic in White Pekin Ducks and Its Amelioration by Using Ginger

Not AvailableThe toxic metalloid arsenic is known to cause liver and kidney injury in many humans and animals. The goal of this paper was to exemplify the antagonism of ginger against arsenic (As)-induced hepato-renal toxicity. In addition, the pathways Nrf2/Keap1 and NF/?B were studied to reveal the molecular mechanism of the stress. One hundred twenty 7-day-old White Pekin ducks were randomly allocated into five groups, having 24 birds in each. Each group contained three replicates having 8 birds in each replicate and maintained for 90 days. The groups were as follows: T-1 [control-basal diet with normal water], T-2 [T1?+?As at 28 ppm/L of water], T-3 [T2?+?ginger powder at 100 mg/kg feed], T-4 [T2?+?ginger powder at 300 mg/kg feed], and T-5 [T2?+?ginger powder at 1 g/kg feed]. It was observed that there was a significant increase in oxidative parameters whereas a significant decrease in antioxidant parameters in hepato-renal tissues in T-2. The exposure to As not only decreased the mRNA expression of antioxidant parameters like Nrf2, SOD-1, CAT, GPX, and HO-1and anti-inflammatory markers like IL-4 and IL-10 but also increased the m-RNA expression of NF-?B, Keap-1 and pro-inflammatory markers like IL-2, Il-6, IL-18, IL-1?, and TNF-?. There was also an accumulation of As in hepatic and renal tissue, confirmed by residual analysis of these tissues. By correlating the above parameters, As at 28 ppm showed significant toxic effects, and ginger powder at 1 g/kg feed effectively counteracted the toxic effects of As in ducks