Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser-2

<p><b>Copyright information:</b></p><p>Taken from "Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser"</p><p>BMC Bioinformatics 2005;6():95-95.</p><p>Published online 12 Apr 2005</p><p>PMCID:PMC1087836.</p><p>Copyright © 2005 Stenger et al; licensee BioMed Central Ltd.</p> (part B) of three data records that define plot coordinates along with other attributes. User databases are created to allow restricted access for uploading data

Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser-1

<p><b>Copyright information:</b></p><p>Taken from "Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser"</p><p>BMC Bioinformatics 2005;6():95-95.</p><p>Published online 12 Apr 2005</p><p>PMCID:PMC1087836.</p><p>Copyright © 2005 Stenger et al; licensee BioMed Central Ltd.</p>age

Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser-0

<p><b>Copyright information:</b></p><p>Taken from "Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser"</p><p>BMC Bioinformatics 2005;6():95-95.</p><p>Published online 12 Apr 2005</p><p>PMCID:PMC1087836.</p><p>Copyright © 2005 Stenger et al; licensee BioMed Central Ltd.</p>aptured using SnagIt 7.0. The figure illustrates the appearance of the Statistic View panel and some of its features in the context of Contig View. It also demonstrates how the selection of a peak can enable the researcher to easily see where linkage data and other features such as potentially unstable tri-nucleotide repeats and gene expression data converge to suggest priority gene for association and sequence analysis

Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser-3

<p><b>Copyright information:</b></p><p>Taken from "Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser"</p><p>BMC Bioinformatics 2005;6():95-95.</p><p>Published online 12 Apr 2005</p><p>PMCID:PMC1087836.</p><p>Copyright © 2005 Stenger et al; licensee BioMed Central Ltd.</p

Schematic of the <i>GATA2</i> Gene Structure

<p>The 12 SNPs representing predicted LD bins in <i>GATA2</i> are shown in black; the five novel SNPs identified through sequencing are shown in grey. † and * indicate a synonymous and nonsynonymous SNP, respectively.</p

Pairwise LD between <i>GATA2</i> SNPs

<p>LD was estimated in one unaffected Caucasian individual from each nonredundant GENECARD discordant sibling pair (<i>n</i> = 279). A similar pattern of LD was observed using the matched probands.</p