Ontology Population via NLP Techniques in Risk Management

In this paper we propose an NLP-based method for Ontology Population from texts and apply it to semi automatic instantiate a Generic Knowledge Base (Generic Domain Ontology) in the risk management domain. The approach is semi-automatic and uses a domain expert intervention for validation. The proposed approach relies on a set of Instances Recognition Rules based on syntactic structures, and on the predicative power of verbs in the instantiation process. It is not domain dependent since it heavily relies on linguistic knowledge. A description of an experiment performed on a part of the ontology of the PRIMA project (supported by the European community) is given. A first validation of the method is done by populating this ontology with Chemical Fact Sheets from Environmental Protection Agency . The results of this experiment complete the paper and support the hypothesis that relying on the predicative power of verbs in the instantiation process improves the performance.Information Extraction, Instance Recognition Rules, Ontology Population, Risk Management, Semantic Analysis

The effect of climate on tourist comfort in Sawa Lake

Climate is one of the variables that influence human health and comfort, and studies show thatregions with slight temperature difference encourage people to overcome their laziness and lethargyand engage in inactive behaviour. Moreover, the changing climate requires joint physical and mentalactivity.Some studies indicate a relationship between efficiency in completing employment or engaging intourism activities and temperature. Efficiency decreases by 57 percent as the temperature dropsbelow zero, and efficiency approaches 25 percent as the temperature drops below zero (from 10 to 10degrees). When it comes to work or activity, when the level of work or activity falls to zero percent,the level of work or activity drops to zero percent and when the temperature is 40°C and above 30°C,human efficiency is 75 percent, but when the temperature is 20°C, the human efficiency is 100percent.As a result, the temperature has an effect, since a temperature rise from 10 ° C to 20 ° C does nothave any effect on a person's mood, but a one degree rise in temperature above 40 ° C causes it to risein summer. In the light of the foregoing, what is the effect of climate on the efficiency and activitiesof tourists, including tourism activity, with rising temperatures

Study the Effect of Cyp19 Gene Polymorphism in Some Genital Hormones and Some Milk Traits in Local Ewes

أجريت هذه الدراسة لغرض دراسة تعدد الاشكال الوراثية polymorphism  لجين CYP19 ومعرفة تاثيرها على تراكيز هرموني الاستروجين والبروجيستيرون في النعاج العواسية المحلية ٬ جمعت عينات الدم من النعاج العواسية في حقول العتبة الحسينية الواقعة على طريق نجف /كربلاء وهذا فيما يخص الجانب الحقلي، تم قياس تراكيز هرمون الاستروجين وهرمون البروجستيرون ٬حيث سجل اعلى تركيز في هرمون الاستروجين (pg/ml16.3349) واقل تركيز(9.3885pg/ml) وكان اعلى تركيز في هرمون البروجيستيرون(0.5893ng/ml ) واقل تركيز (ng/ml0.1302) تم عزل الحزمة الجينية للاكسون الثالث التابعة للجينCYP19 البالغ حجمها140 bp وتحديد التراكيب الوراثية Genotype)) لها تبعا لاختلاف تسلسل النيوكليوتيدات وعلاقتها بتراكيز الاستروجين و البروجيستيرون في عينات الدراسة كانت نسب توزيع التراكيب الوراثية لجين CYP19في عينة النعاج العواسية المحلية %6.25 و%31.25و%62.50 لكل من التراكيب الوراثية TT  و TCوCC على التتابع، واظهرت نتائج قياس تركيز الاستروجين تفوقاً معنوياً على مستوى احتمالية (P≤0.05 ) في الطراز الوراثي TT و TC (15,5745,15,4617) على التوالي مقارنة بالطراز الوراثيCC ( 14.2362)في حين لم يكن هنالك فرق معنوي بين   الطرازين الوراثيين TTوTC.أوضحت نتائج قياس تركيز البروجيستيرون تفوقاً معنوياً على مستوى احتمالية P≤0.05 في الطراز الوراثي TC (.47770)على الطرازين الوراثيين TT و CC (0.3288,0.2469)بينما انخفض تركيز البروجيستيرون للطراز الوراثي TT انخفاظا معنويا مقارنة بالطراز الوراثي TC و CC. توصلت الدراسة الحالية الى شيوع التركيب الوراثي TCلجينCYP19 على التركيبين الوراثيين TTوCCوان لتعدد الاشكال الوراثي Polymorphism لجين CYP19 في Exon3 تاثيراً معنوياً  على تراكيز الاستروجيين والبروجيستيرون  إذ تفوقت الافراد الحاملة للتركيب الوراثي TC لجين CYP19 على التراكيب الوراثية TT وCCفي تراكيز هرموني الاستروجين والبروجيستيرون.This study was carried out for the studying CYP19 gene polymorphism and its effect in concentrations of estrogen and progesterone in local ectopic ewes. Blood samples were collected from ewes in the fields of Husseiniya on the Najaf / Karbala road. In terms of the field side, estrogen concentrations The highest concentration of progesterone (0.5893 ng / ml) and the lowest concentration (ng / ml0.1302) was the isolation of the genetic bundle For the third CYP19 genome of 140 bp and the determination of the structures Genotype). The genotype of the CYP19 gene in the sample of local ewes was 6.25%, 31.25%, and 62.50% for the TT, TC and CC sequences in the sequence. Concentration measurement results Estrogen had a significant effect on the level of P (0.05) in the genotype TT and TC (15,5745,15,4617) respectively, compared with the CC model (14.2362), while there was no significant difference between the TT and TC models. Progesterone significantly exceeded the P00.05 probability level in the Ur model (0.47770) on the genotype TT and CC (0.3288,0.2469). The progesterone concentration of the TT genotype decreased significantly compared with TC and CC. The study found that the genetic makeup of the gene CYP19 on the genetic structures of TT and CCW and the polymorphism of CYP19 gene in Exon3 had a significant effect on estrogens and progesterone concentrations. Individuals carrying the genetic makeup of the gene CYP19 were superior to the TT and CC structures in estrogen and progesterone concentrations

ENVIRONMENTAL ASSESSMENT OF AL-HILLAH RIVER POLLUTION AT BABIL GOVERNORATE (IRAQ)

In this study, the environmental characteristics of Al-Hillah River were studied using geoinformatics applications, which is one of the geospatial techniques (GST). Applying this methodology, a geographic information system was developed, and it was supplied with laboratory data for the physical and chemical properties of 16 parameters for 2021. These data were linked to their spatial locations, using radar imagery of the Digital Elevation Model (Shuttle Radar Topography Mission), and Landsat ETM+7 satellite image. The results indicated that Al-Hillah River was affected by the liquid discharges of factories, cities, and farms spread on its sides, especially in the cities of Sadat Al-Hindiya, Al-Hillah, and Al-Hashimiyah. The seasonal changes in the climate affected some characteristics, including water temperature, pH, turbidity, total dissolved solids, and total hardness. The study showed that the concentration of sulfate (SO4) has risen above the permissible limits for the waters of Iraqi rivers. There are relatively high hardness and alkalinity values, but they were within the permissible limits. The study also showed that most of the results of environmental parameters that were used in the laboratory, were within the permissible limits of Iraqi water, except for sulfates. The justification for conducting this study is to help government agencies and decision-makers to adopt a correct vision for development projects that serve Babil Governorate. Also, it is the first time that the environmental characteristics of Al-Hillah River are studied using geoinformatics applications

Measuring routine childhood vaccination coverage in 204 countries and territories, 1980-2019 : a systematic analysis for the Global Burden of Disease Study 2020, Release 1

Background Measuring routine childhood vaccination is crucial to inform global vaccine policies and programme implementation, and to track progress towards targets set by the Global Vaccine Action Plan (GVAP) and Immunization Agenda 2030. Robust estimates of routine vaccine coverage are needed to identify past successes and persistent vulnerabilities. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020, Release 1, we did a systematic analysis of global, regional, and national vaccine coverage trends using a statistical framework, by vaccine and over time. Methods For this analysis we collated 55 326 country-specific, cohort-specific, year-specific, vaccine-specific, and dosespecific observations of routine childhood vaccination coverage between 1980 and 2019. Using spatiotemporal Gaussian process regression, we produced location-specific and year-specific estimates of 11 routine childhood vaccine coverage indicators for 204 countries and territories from 1980 to 2019, adjusting for biases in countryreported data and reflecting reported stockouts and supply disruptions. We analysed global and regional trends in coverage and numbers of zero-dose children (defined as those who never received a diphtheria-tetanus-pertussis [DTP] vaccine dose), progress towards GVAP targets, and the relationship between vaccine coverage and sociodemographic development. Findings By 2019, global coverage of third-dose DTP (DTP3; 81.6% [95% uncertainty interval 80.4-82 .7]) more than doubled from levels estimated in 1980 (39.9% [37.5-42.1]), as did global coverage of the first-dose measles-containing vaccine (MCV1; from 38.5% [35.4-41.3] in 1980 to 83.6% [82.3-84.8] in 2019). Third- dose polio vaccine (Pol3) coverage also increased, from 42.6% (41.4-44.1) in 1980 to 79.8% (78.4-81.1) in 2019, and global coverage of newer vaccines increased rapidly between 2000 and 2019. The global number of zero-dose children fell by nearly 75% between 1980 and 2019, from 56.8 million (52.6-60. 9) to 14.5 million (13.4-15.9). However, over the past decade, global vaccine coverage broadly plateaued; 94 countries and territories recorded decreasing DTP3 coverage since 2010. Only 11 countries and territories were estimated to have reached the national GVAP target of at least 90% coverage for all assessed vaccines in 2019. Interpretation After achieving large gains in childhood vaccine coverage worldwide, in much of the world this progress was stalled or reversed from 2010 to 2019. These findings underscore the importance of revisiting routine immunisation strategies and programmatic approaches, recentring service delivery around equity and underserved populations. Strengthening vaccine data and monitoring systems is crucial to these pursuits, now and through to 2030, to ensure that all children have access to, and can benefit from, lifesaving vaccines. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.Peer reviewe

Assessing performance of the Healthcare Access and Quality Index, overall and by select age groups, for 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019

Background: Health-care needs change throughout the life course. It is thus crucial to assess whether health systems provide access to quality health care for all ages. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019), we measured the Healthcare Access and Quality (HAQ) Index overall and for select age groups in 204 locations from 1990 to 2019. Methods: We distinguished the overall HAQ Index (ages 0–74 years) from scores for select age groups: the young (ages 0–14 years), working (ages 15–64 years), and post-working (ages 65–74 years) groups. For GBD 2019, HAQ Index construction methods were updated to use the arithmetic mean of scaled mortality-to-incidence ratios (MIRs) and risk-standardised death rates (RSDRs) for 32 causes of death that should not occur in the presence of timely, quality health care. Across locations and years, MIRs and RSDRs were scaled from 0 (worst) to 100 (best) separately, putting the HAQ Index on a different relative scale for each age group. We estimated absolute convergence for each group on the basis of whether the HAQ Index grew faster in absolute terms between 1990 and 2019 in countries with lower 1990 HAQ Index scores than countries with higher 1990 HAQ Index scores and by Socio-demographic Index (SDI) quintile. SDI is a summary metric of overall development. Findings: Between 1990 and 2019, the HAQ Index increased overall (by 19·6 points, 95% uncertainty interval 17·9–21·3), as well as among the young (22·5, 19·9–24·7), working (17·2, 15·2–19·1), and post-working (15·1, 13·2–17·0) age groups. Large differences in HAQ Index scores were present across SDI levels in 2019, with the overall index ranging from 30·7 (28·6–33·0) on average in low-SDI countries to 83·4 (82·4–84·3) on average in high-SDI countries. Similarly large ranges between low-SDI and high-SDI countries, respectively, were estimated in the HAQ Index for the young (40·4–89·0), working (33·8–82·8), and post-working (30·4–79·1) groups. Absolute convergence in HAQ Index was estimated in the young group only. In contrast, divergence was estimated among the working and post-working groups, driven by slow progress in low-SDI countries. Interpretation: Although major gaps remain across levels of social and economic development, convergence in the young group is an encouraging sign of reduced disparities in health-care access and quality. However, divergence in the working and post-working groups indicates that health-care access and quality is lagging at lower levels of social and economic development. To meet the needs of ageing populations, health systems need to improve health-care access and quality for working-age adults and older populations while continuing to realise gains among the young. Funding: Bill & Melinda Gates Foundation

The global burden of adolescent and young adult cancer in 2019 : a systematic analysis for the Global Burden of Disease Study 2019

Background In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. Comprehensive estimates of the global cancer burden in adolescents and young adults (aged 15-39 years) are lacking. To address this gap, we analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, with a focus on the outcome of disability-adjusted life-years (DALYs), to inform global cancer control measures in adolescents and young adults. Methods Using the GBD 2019 methodology, international mortality data were collected from vital registration systems, verbal autopsies, and population-based cancer registry inputs modelled with mortality-to-incidence ratios (MIRs). Incidence was computed with mortality estimates and corresponding MIRs. Prevalence estimates were calculated using modelled survival and multiplied by disability weights to obtain years lived with disability (YLDs). Years of life lost (YLLs) were calculated as age-specific cancer deaths multiplied by the standard life expectancy at the age of death. The main outcome was DALYs (the sum of YLLs and YLDs). Estimates were presented globally and by Socio-demographic Index (SDI) quintiles (countries ranked and divided into five equal SDI groups), and all estimates were presented with corresponding 95% uncertainty intervals (UIs). For this analysis, we used the age range of 15-39 years to define adolescents and young adults. Findings There were 1.19 million (95% UI 1.11-1.28) incident cancer cases and 396 000 (370 000-425 000) deaths due to cancer among people aged 15-39 years worldwide in 2019. The highest age-standardised incidence rates occurred in high SDI (59.6 [54.5-65.7] per 100 000 person-years) and high-middle SDI countries (53.2 [48.8-57.9] per 100 000 person-years), while the highest age-standardised mortality rates were in low-middle SDI (14.2 [12.9-15.6] per 100 000 person-years) and middle SDI (13.6 [12.6-14.8] per 100 000 person-years) countries. In 2019, adolescent and young adult cancers contributed 23.5 million (21.9-25.2) DALYs to the global burden of disease, of which 2.7% (1.9-3.6) came from YLDs and 97.3% (96.4-98.1) from YLLs. Cancer was the fourth leading cause of death and tenth leading cause of DALYs in adolescents and young adults globally. Interpretation Adolescent and young adult cancers contributed substantially to the overall adolescent and young adult disease burden globally in 2019. These results provide new insights into the distribution and magnitude of the adolescent and young adult cancer burden around the world. With notable differences observed across SDI settings, these estimates can inform global and country-level cancer control efforts. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.Peer reviewe

Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey

Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10 years; 78.2% included were male with a median age of 37 years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020

The global burden of cancer attributable to risk factors, 2010-19 : a systematic analysis for the Global Burden of Disease Study 2019

Background Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. Findings Globally, in 2019, the risk factors included in this analysis accounted for 4.45 million (95% uncertainty interval 4.01-4.94) deaths and 105 million (95.0-116) DALYs for both sexes combined, representing 44.4% (41.3-48.4) of all cancer deaths and 42.0% (39.1-45.6) of all DALYs. There were 2.88 million (2.60-3.18) risk-attributable cancer deaths in males (50.6% [47.8-54.1] of all male cancer deaths) and 1.58 million (1.36-1.84) risk-attributable cancer deaths in females (36.3% [32.5-41.3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20.4% (12.6-28.4) and DALYs by 16.8% (8.8-25.0), with the greatest percentage increase in metabolic risks (34.7% [27.9-42.8] and 33.3% [25.8-42.0]). Interpretation The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.Peer reviewe