2,257 research outputs found
A source unit in apparatus and tumbling for boys in the secondary school.
Thesis (Ed.M.)--Boston Universit
Epithelial cell migration as a potential therapeutic target in early lung cancer.
Lung cancer is the most lethal cancer type worldwide, with the majority of patients presenting with advanced stage disease. Targeting early stage disease pathogenesis would allow dramatic improvements in lung cancer patient survival. Recently, cell migration has been shown to be an integral process in early lung cancer ontogeny, with preinvasive lung cancer cells shown to migrate across normal epithelium prior to developing into invasive disease. TP53 mutations are the most abundant mutations in human nonsmall cell lung cancers and have been shown to increase cell migration via regulation of Rho-GTPase protein activity. In this review, we explore the possibility of targeting TP53-mediated Rho-GTPase activity in early lung cancer and the opportunities for translating this preclinical research into effective therapies for early stage lung cancer patients
XO-5b: A Transiting Jupiter-sized Planet With A Four Day Period
The star XO-5 (GSC 02959-00729, V=12.1, G8V) hosts a Jupiter-sized,
Rp=1.15+/-0.12 Rjup, transiting extrasolar planet, XO-5b, with an orbital
period of P=4.187732+/-0.00002 days. The planet mass (Mp=1.15+/-0.08 Mjup) and
surface gravity (gp=22+/-5 m/s^2) are significantly larger than expected by
empirical Mp-P and Mp-P-[Fe/H] relationships. However, the deviation from the
Mp-P relationship for XO-5b is not large enough to suggest a distinct type of
planet as is suggested for GJ 436b, HAT-P-2b, and XO-3b. By coincidence XO-5
overlies the extreme H I plume that emanates from the interacting galaxy pair
NGC 2444/NGC 2445 (Arp 143).Comment: 10 pages, 9 Figures, Submitted to Ap
Wide binaries demonstrate the consistency of rotational evolution between open cluster and field stars
Gyrochronology enables the derivation of ages of late-type main sequence
stars based on their rotation periods and a mass proxy, such as color. It has
been explored in open clusters, but a connection to field stars has yet to be
successfully established. We explore the rotation rates of wide binaries,
representing enlightening intermediaries between clusters and field stars, and
their overlap with those of open cluster stars. We investigated a recently
created catalog of wide binaries, matched the cataloged binaries to
observations by the Kepler mission (and its K2 extension), validated or
re-derived their rotation periods, identified 283 systems where both stars are
on the main sequence and have vetted rotation periods, and compared the systems
with open cluster data. We find that the vast majority of these wide binaries
(236) line up directly along the curvilinear ribs defined by open clusters in
color-period diagrams or along the equivalent interstitial gaps between
successive open clusters. The parallelism in shape is remarkable. Twelve
additional systems are clearly rotationally older. The deviant systems, a
minority, are mostly demonstrably hierarchical. Furthermore, the position of
the evolved component in the color-magnitude diagram for the additional wide
binary systems that contain one is consistent with the main sequence
component's rotational age. We conclude that wide binaries, despite their
diversity, follow the same spindown relationship as observed in open clusters,
and we find that rotation-based age estimates yield the same ages for both
components in a wide binary. This suggests that cluster and field stars spin
down in the same way and that gyrochronology can be applied to field stars to
determine their ages, provided that they are sufficiently distant from any
companions to be considered effectively single.Comment: 23 pages, 19 figures, published in A&A 675, A180 (2023
Feeding crops to sheep
WESTERN AUSTRALIA\u27S 1969-70 drought provided the need for agricultural research workers to investigate methods of feeding stock under severe environmental conditions.
This report presents brief descriptions of two such investigations. Further details of the experiments can be obtained by contacting the authors
Optical photometry and basic parameters of 10 unstudied open clusters
We present BVI CCD photometry of 10 northern open clusters, Berkeley 43, Berkeley 45, Berkeley 47, NGC 6846, Berkeley 49, Berkeley 51, Berkeley 89, Berkeley 91, Tombaugh 4 and Berkeley 9, and estimate their fundamental parameters. Eight of the clusters are located in the first Galactic quadrant and two are in the second. This is the first optical photometry for eight clusters. All of them are embedded in rich Galactic fields and have large reddening towards them [E(B−V) = 1.0–2.3 mag]. There is a possibility that some of these difficult-to-study clusters may be asterisms rather than physical systems, but assuming that they are physical clusters, we find that eight of them are located beyond 2 kpc and six clusters (60 per cent of the sample) are located well above or below the Galactic plane. Seven clusters have ages 500 Myr or less and the other three are 1 Gyr or more in age. This sample of clusters has increased the optical photometry of clusters in the second half of the first Galactic quadrant, beyond 2 kpc, from 10 to 15. NGC 6846 is found to be one of the most distant clusters in this region of the Galaxy
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