5 research outputs found
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation
- Author
- A Kentsis
- A Pulsoni
- Abdellatif Amri
- Andrea A. Romeo
- B Culjkovic-Kraljacic
- B Deschler
- B Deschler
- BC Kraljacic
- BD Cheson
- Biljana Culjkovic-Kraljacic
- Brian Leber
- C Mas
- Craig T. Jordan
- E Olah
- Eftihia Cocolakis
- G Dutton
- Gregory Cormack
- Hiba Ahmad Zahreddine
- HP Horny
- James B. Jaquith
- JJ Engtrakul
- Julie Bergeron
- Katherine L. B. Borden
- Leandro Cerchietti
- M Lauth
- MB Fisher
- Michael W. Becker
- O Barbier
- Patrick Gendron
- PM LoRusso
- RC Willis
- RH Tukey
- S Anders
- S Assouline
- Sarit Assouline
- Shanshan Pei
- SM Jarvis
- Stephen J. Morris
- W Hiddemann
- Wilson H. Miller
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
No full textRegioselective Glucuronidation of Andrographolide and Its Major Derivatives: Metabolite Identification, Isozyme Contribution, and Species Differences
- Author
- A Panossian
- B Shukla
- Baojian Wu
- BC Yu
- BJ Wu
- BL Coffman
- Chao Wang
- E Lévesque
- F Qiu
- GB Ge
- GF Dai
- Guangbo Ge
- HY Zhao
- I Takeshi
- J Li
- J Wang
- JC Stingl
- JJ Engtrakul
- JK Ritter
- Kexin Liu
- KM Knights
- L Cui
- L Cui
- L Cui
- L Zhu
- Ling Yang
- M Chen
- M Yang
- MH Court
- MM Uttekar
- NP Trivedi
- OF Iwuchukwu
- P Thisoda
- Q Lin
- Q Zhou
- R Meech
- RH Tukey
- S Deng
- Sa Deng
- Sicheng Liang
- SR Jada
- V Uchaipichat
- W Liu
- WW Chao
- Xiangge Tian
- Xiaochi Ma
- XL Xin
- YJ He
- YQ He
- Publication venue
- 'American Association of Pharmaceutical Scientists (AAPS)'
- Publication date
- Field of study
No full textRationalizing underprediction of drug clearance from enzyme and transporter kinetic data: From in vitro tools to mechanistic modeling
- Author
- A Aitio
- A Dokoumetzidis
- A Galetin
- A Galetin
- A Guillouzo
- A Poirier
- A Poirier
- A Poirier
- A Rostami-Hodjegan
- A Rostami-Hodjegan
- A Rowland
- A Rowland
- A Rowland
- AF Sasso
- AJ Parker
- AN Edginton
- AS Darwich
- B Agoram
- B Davies
- BJ Ring
- C Ghobadi
- C Sall
- D Dalvie
- D Hallifax
- D Hallifax
- D Hallifax
- D Hallifax
- D Tam
- DC Pryde
- DJ Carlile
- E Jigorel
- E Kimoto
- E Steeg van de
- F Bouzom
- G Camenisch
- H Hiraoka
- H Kusuhara
- H Kusuhara
- H Lennernas
- H Zhang
- HE Cubitt
- HE Cubitt
- HM Jones
- HM Jones
- HM Jones
- HM Jones
- HS Brown
- I Nestorov
- I Nestorov
- IA Nestorov
- International Commission on Radiological Protection
- J Yang
- JA Grillo
- JB Houston
- JB Houston
- JJ Engtrakul
- JK Lee
- JM Hutzler
- JO Miners
- K Ball
- K Ito
- K Ito
- K Ito
- K Menochet
- K Menochet
- K Rowland Yeo
- K Sugano
- K Yoshida
- KL Gill
- KL Gill
- KM Giacomini
- KP Kanebratt
- KR Korzekwa
- KS Pang
- KS Pang
- KS Pang
- L Badolo
- L Di
- L Di
- L Sivertsson
- LX Yu
- LX Yu
- M Baker
- M Chiba
- M Darnell
- M Gertz
- M Gertz
- M Gertz
- M Gertz
- M Jamei
- M Jamei
- M Jamei
- M Rowland
- M Ulvestad
- M Ulvestad
- M Zientek
- MA Mohutsky
- MB Fisher
- MD Harwood
- MF Paine
- MF Paine
- MG Soars
- MG Soars
- MG Soars
- MJ Zamek-Gliszczynski
- MV Varma
- MV Varma
- N Chalasani
- N Kotani
- N Parrott
- O Schaefer
- P Gaganis
- P Poulin
- P Poulin
- P Zhao
- P Zhao
- PJ Kilford
- PJ Kilford
- PJ Webborn
- RJ Riley
- RK Kuester
- RP Brown
- RS Obach
- RS Obach
- S Berggren
- S Bjorkman
- S Ohtsuki
- SK Quinney
- SK Quinney
- SM Huang
- SS Buck De
- T Lave
- T Takashima
- T Watanabe
- T Watanabe
- TG Tucker
- U Zanelli
- VK Sinha
- WS Al-Jahdari
- X Chu
- X Zhang
- Y Chen
- Y Shitara
- Y Shitara
- Y Yabe
- YA Bi
- ZE Barter
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
No full textChallenges and Opportunities with Non-CYP Enzymes Aldehyde Oxidase, Carboxylesterase, and UDP-Glucuronosyltransferase: Focus on Reaction Phenotyping and Prediction of Human Clearance
- Author
- A Galetin
- A Rowland
- A Rowland
- A Tornio
- AA Guemei
- B Kaye
- BM Young
- BR Baer
- BW Ogilvie
- C Beedham
- C Beedham
- C Coelho
- C Dittrich
- C Fu
- CL Morton
- CL Morton
- CL Morton
- CL Morton
- CR Gibson
- D Dalvie
- E Garattini
- E Garattini
- EI Parkinson
- ER Soares
- ET Williams
- ET Williams
- F Lombardo
- F Lombardo
- H Nishimuta
- H-X Zhou
- HE Cubitt
- HE Cubitt
- HJ Zhu
- HJ Zhu
- HJ Zhu
- HS Al-Salmy
- J Cashman
- J Zhou
- J. Matthew Hutzler
- JA Williams
- JJ Engtrakul
- JK Fallon
- JK Sodhi
- JL Bushee
- JL Bushee
- JL Hyatt
- JL Hyatt
- JL Hyatt
- JL Hyatt
- JM Hutzler
- JM Hutzler
- JM Hutzler
- JO Miners
- JO Miners
- JT Barr
- K Sugihara
- KL Gill
- L Oleson
- LD Hicks
- LD Hicks
- LG Tsurkan
- M Gunduz
- M Kurosaki
- M Mistry
- M Nishimura
- M Strolin Benedetti
- M Terao
- M Wierdl
- M Zientek
- MA Zientek
- MB Fisher
- MG Soars
- MG Soars
- MJ Hatfield
- MJ Hatfield
- MJ Hatfield
- MJ Hatfield
- MK Danks
- MK Gilson
- MR Redinbo
- N Chauret
- N Manevski
- N Manevski
- NA Hosea
- P Kestell
- Philip M. Potter
- PI Mackenzie
- PI Mackenzie
- PI Mackenzie
- PJ Kilford
- PM Potter
- Punit H. Marathe
- R Fujiwara
- R Humerickhouse
- R Khanna
- R Nirogi
- RL Walsky
- RM Wadkins
- RM Wadkins
- RM Wadkins
- RP Remmel
- RP Remmel
- RP Remmel
- RS Holmes
- RS Obach
- S Bencharit
- S Bencharit
- S Bencharit
- S Boase
- S Diamond
- S Kitamura
- S Kitamura
- S Krishnaswamy
- SC Laizure
- T Akabane
- T Akabane
- T Akabane
- T Deguchi
- TJ Strelevitz
- UA Argikar
- UA Argikar
- Upendra A. Argikar
- V Uchaipichat
- X Zhang
- Y Moriwaki
- Y Naritomi
- Y Shitara
- Y Tayama
- ZY Hu
- Publication venue
- 'American Association of Pharmaceutical Scientists (AAPS)'
- Publication date
- Field of study
No full textRationalizing Underprediction of Drug Clearance from Enzyme and Transporter Kinetic Data: From In Vitro Tools to Mechanistic Modeling
- Author
- A Aitio
- A Dokoumetzidis
- A Galetin
- A Galetin
- A Guillouzo
- A Poirier
- A Poirier
- A Poirier
- A Rostami-Hodjegan
- A Rostami-Hodjegan
- A Rowland
- A Rowland
- A Rowland
- AF Sasso
- AJ Parker
- AN Edginton
- AS Darwich
- B Agoram
- B Davies
- BJ Ring
- C Ghobadi
- C Sall
- D Dalvie
- D Hallifax
- D Hallifax
- D Hallifax
- D Hallifax
- D Tam
- DC Pryde
- DJ Carlile
- E Jigorel
- E Kimoto
- E Steeg van de
- F Bouzom
- G Camenisch
- H Hiraoka
- H Kusuhara
- H Kusuhara
- H Lennernas
- H Zhang
- HE Cubitt
- HE Cubitt
- HM Jones
- HM Jones
- HM Jones
- HM Jones
- HS Brown
- I Nestorov
- I Nestorov
- IA Nestorov
- International Commission on Radiological Protection
- J Yang
- JA Grillo
- JB Houston
- JB Houston
- JJ Engtrakul
- JK Lee
- JM Hutzler
- JO Miners
- K Ball
- K Ito
- K Ito
- K Ito
- K Menochet
- K Menochet
- K Rowland Yeo
- K Sugano
- K Yoshida
- KL Gill
- KL Gill
- KM Giacomini
- KP Kanebratt
- KR Korzekwa
- KS Pang
- KS Pang
- KS Pang
- L Badolo
- L Di
- L Di
- L Sivertsson
- LX Yu
- LX Yu
- M Baker
- M Chiba
- M Darnell
- M Gertz
- M Gertz
- M Gertz
- M Gertz
- M Jamei
- M Jamei
- M Jamei
- M Rowland
- M Ulvestad
- M Ulvestad
- M Zientek
- MA Mohutsky
- MB Fisher
- MD Harwood
- MF Paine
- MF Paine
- MG Soars
- MG Soars
- MG Soars
- MJ Zamek-Gliszczynski
- MV Varma
- MV Varma
- N Chalasani
- N Kotani
- N Parrott
- O Schaefer
- P Gaganis
- P Poulin
- P Poulin
- P Zhao
- P Zhao
- PJ Kilford
- PJ Kilford
- PJ Webborn
- RJ Riley
- RK Kuester
- RP Brown
- RS Obach
- RS Obach
- S Berggren
- S Bjorkman
- S Ohtsuki
- SK Quinney
- SK Quinney
- SM Huang
- SS Buck De
- T Lave
- T Takashima
- T Watanabe
- T Watanabe
- TG Tucker
- U Zanelli
- VK Sinha
- WS Al-Jahdari
- X Chu
- X Zhang
- Y Chen
- Y Shitara
- Y Shitara
- Y Yabe
- YA Bi
- ZE Barter
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
No full text
