238 research outputs found
Theoretical Validity and Empirical Utility of a Constructionist Analytics
Wing-Chung Ho offers an extensive critique of what he calls our “radical constructionist approach to family experience,” questioning the theoretical validity and empirical utility of the research program. This article responds to the charges in the broader context of the program\u27s constructionist analytics, discussing family\u27s experiential location, organizational embeddedness, and the importance of ethnographic sensibility. A brief extract of situated talk and interaction is presented to illustrate the discursive complexity and institutional bearings of family as a category of experience. The conclusion takes up the issue of whether the program is radical in conceptualization and empirical realization
Don\u27t Argue with the Members
Mel Pollner regularly cautioned researchers not to argue with the members of settings under consideration. He warned against substituting the researcher’s meaning for the meanings of those being studied. This article discusses facets of the caution as they relate to the research process. Seemingly simple, the tenet is nuanced in application. The article adds to the nuance by distinguishing what is called the “replacement” of meaning with the “displacement” of meaning, providing a way of understanding what members could mean if the contexts and settings of their accounts were taken into consideration
Animating Interview Narratives
This chapter discusses the implications of viewing the interview as an actively constructed conversation through which narrative data are produced. It explores the ramifications of framing the interview and resulting data as by-products of interpretive practice - the whats and hows of an animated process involving active subjects behind interview participants. Matters of reliability, validity, bias, and rigor are considered
The Role of Osteocytes in Targeted Bone Remodeling: A Mathematical Model
Until recently many studies of bone remodeling at the cellular level have
focused on the behavior of mature osteoblasts and osteoclasts, and their
respective precursor cells, with the role of osteocytes and bone lining cells
left largely unexplored. This is particularly true with respect to the
mathematical modeling of bone remodeling. However, there is increasing evidence
that osteocytes play important roles in the cycle of targeted bone remodeling,
in serving as a significant source of RANKL to support osteoclastogenesis, and
in secreting the bone formation inhibitor sclerostin. Moreover, there is also
increasing interest in sclerostin, an osteocyte-secreted bone formation
inhibitor, and its role in regulating local response to changes in the bone
microenvironment. Here we develop a cell population model of bone remodeling
that includes the role of osteocytes, sclerostin, and allows for the
possibility of RANKL expression by osteocyte cell populations. This model
extends and complements many of the existing mathematical models for bone
remodeling but can be used to explore aspects of the process of bone remodeling
that were previously beyond the scope of prior modeling work. Through numerical
simulations we demonstrate that our model can be used to theoretically explore
many of the most recent experimental results for bone remodeling, and can be
utilized to assess the effects of novel bone-targeting agents on the bone
remodeling process
Photon Rates for Heavy-Ion Collisions from Hidden Local Symmetry
We study photon production from the hidden local symmetry approach that
includes pions, rho and a1 mesons and compute the corresponding photon emission
rates from a hadronic gas in thermal equilibrium. Together with experimental
radiative decay widths of the background, these rates are used in a
relativistic transport model to calculate single photon spectra in heavy-ion
collisions at SPS energies. We then employ this effective theory to test three
scenarios for the chiral phase transition in high-temperature nuclear matter
including decreasing vector meson masses. Although all calculations respect the
upper bound set by the WA80 Collaboration, we find the scenarios could be
distinguished with more detailed data.Comment: 12 pages, 12 Postscript figures; discussion of thermal equilibrium
rates expanded, minor corrections to text and graph
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