Dynamical Modulation of Wintertime Synoptic-Scale Cyclone Activity over the Japan Sea due to Changbai Mountain in the Korean Peninsula

The dynamical impact of the Changbai Mountain Range in the Korean Peninsula on the extratropical cyclone activity over the Japan Sea in early winter is examined using the Weather Research Forecasting model. We have conducted two independent long-term integrations over 15 winter months (December only) from 2000 to 2014 with and without modified topography. The results show that the Changbai Mountain Range plays a vital role in increasing cyclone track frequency, low-level poleward eddy heat flux, and the local deepening rate over the Japan Sea through enhancement of the lower-tropospheric baroclinic zone (LTBZ). This mountain range gives rise to activation of the synoptic-scale cyclone activity over that region. From our case study on three typical cyclones, it is found that mesoscale structures in the vicinity of a cyclone’s center are dynamically modulated when it passes through the LTBZ and that cyclogenesis is triggered around that zone. A vorticity budget analysis shows that the stretching term relevant to enhanced low-level convergence plays a dominant role in intensifying cyclonic vorticities. We confirmed that the composite features of the three typical cases are consistent with the statistical ones of the dynamical modulation of the Changbai Mountain on synoptic-scale cyclone activity

Enhancing Light-Absorption and Luminescent Properties of Non-Emissive 1,3,4,6,9b-Pentaazaphenalene through Perturbation of Forbidden Electronic Transition by Boron Complexation

We report an improvement of optical properties of the non‐emissive molecule through shuffling the molecular orbitals by boron complexation. The 1, 3, 4, 6, 9b‐pentaazaphenelene (5AP) derivative having a 2‐(dimesitylboryl)phenyl group was synthesized through a substitution reaction from a 2‐bromophenyl compound. The formation of the B−N dative bond was confirmed by ¹¹B{¹H} NMR spectroscopy and a single‐crystal X‐ray structure analysis. Most of the conventional 5AP derivatives hardly showed emission despite their planar and rigid molecular structures. The previous reports on 5AP derivatives ascribed the non‐luminescent behavior to the forbidden transition between frontier orbitals. On the other hand, the 5AP‐based boron complex in this work showed enhanced light absorption and luminescence from the HOMO−LUMO transition. Theoretical calculations suggested that the boron complexation should play a critical role in perturbing the forbidden character of the HOMO−LUMO transition. Because the nitrogen atom on the 5AP moiety formed the Lewis acid−base pair with the boron atom, the energy level of the HOMO of 5AP was downshifted. The character of the HOMO−LUMO transition of the boron complex was changed to afford the improved optical properties of the boron complex

An Analysis over the Thoughts of Atomic Bomb Survivors : From the Viewpoints of Hatred and Sense of Responsibility for Atomic Bomb Devastation

The purpose of this paper is to make an attempt to draw a wider perspective on the feelings of Atomic Bomb Survivors in Hiroshima and Nagasaki by looking at their antagonistic thoughts. Such “negative” side of Atomic Bomb Survivors do not appear on surface in public since their core feeling for accomplishing peace is understood as “wishing for the world without nuclear weapons”. This paper analyzes two different surveys conducted by the Asahi Shimbun and the Yomiuri Shimbun. What was revealed after such analysis was that although more than 70% of the Atomic Bomb Survivors once had actually hated USA, many of them did not hate USA any more by the time of the survey. While the reason for such result – the majority of the Atomic Bomb Survivors do not hate USA any more – is not yet clear enough, this study has intention to make further analysis on the thoughts and feelings of the Atomic Bomb Survivors by making interview to them in the coming days.本稿は、科学研究費（課題番号15H03137）による研究成果の一部である

Clinical Features of Intestinal Behçet's Disease Associated with Myelodysplastic Syndrome and Trisomy 8

Several studies have identified a relationship between myelodysplastic syndrome and Behçetʼs disease (BD), especially intestinal BD, and trisomy 8 appears to play an important role in these disorders. Despite this, only few case reports or series have been reported in gastroenterology, meaning that endoscopic findings and characteristics of intestinal BD have not been clarified yet. In this report, we describe three cases of intestinal BD associated with myelodysplastic syndrome and trisomy 8, and discuss the clinical features and problems of these disorders from a gastroenterology perspective

Reality of Gastric Cancer in Young Patients: The Importance and Difficulty of the Early Diagnosis, Prevention and Treatment

Gastric cancer usually arises in middle-aged to older patients, and is rarely found in younger patients. The clin-ical characteristics, etiology, prognosis, preventive methods and treatment of gastric cancer in young patients have not been fully investigated because of its low prevalence. In this review, we discuss the current under-standing and clinical problems associated with gastric cancer in young patients. Helicobacter pylori (H. pylori), which is a major cause of gastric cancer, especially in older populations, is closely associated with gastric cancer in young patients as well as in older patients. Gastric cancer in young patients tends to be diagnosed at an advanced stage with alarm symptoms. However, young patients with advanced gastric cancer tend to have a favorable general condition and organ function, so they can tolerate intensive systematic chemotherapy. Unfortunately, the prognosis of gastric cancer in young patients with an advanced stage is not favorable. We should not take this rare disease lightly, given its poor prognosis if patients are diagnosed at an unresectable stage. The evaluation of the H. pylori infection status and performance of H. pylori eradication therapy to prevent gastric cancer in young patients as well as the development of more intensive chemotherapy regimens for unre-sectable gastric cancer in young patients are warranted

Factors Associated with Cognitive Decline in Elderly Diabetics

www.karger.com/dee This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License (www.karger.com/OA-license), applicable to the online version of the article only. Distribution for non-commercial purposes only.

Eosinophilic Gastritis in a Patient Previously Treated with Dupilumab

A 77-year-old Japanese man with bronchial asthma was treated with dupilumab. Dupilumab treatment was discontinued at the patient's request after two injections separated by a 2-week interval. The blood eosinophil count was elevated, and an esophagogastroduodenoscopy performed 3 months after dupilumab treatment revealed gastric ulcers; subsequently, eosinophilic gastritis was diagnosed from biopsy examinations. The gastric lesions were resolved by steroid administration. This case report underscores that eosinophil-associated gastrointestinal diseases should be considered in the differential diagnosis of gastric lesions occurring in patients who were treated with dupilumab