Closing of the American Mind (Book Review)

Reviewed Title: The Closing of the American Mind. Allan Bloom. New York: Simon and Schuster, 1987, 392 pp

Christianity on Trial (Book Review)

Reviewed Title: Christianity on Trial, by Colin Chapman, Tyndale House, Wheaton, Illinois

Bread for the World (Book Review)

Reviewed Title: Bread for the World, by Arthur Simon, Paulist Press, New York, and Wm. B. Eerdmans Publishing Co., Grand Rapids, Michigan, 179 pages

AMERICANS AND GM FOOD: KNOWLEDGE, OPINION AND INTEREST IN 2004

This report presents the results from the third in a series of studies examining public perception of genetically modified (GM) food in the United States. All three studies were based on survey results of separate, nationally representative samples of approximately 1,200 Americans taken in 2001, 2003, and 2004. While the survey instrument on which the current report is based maintained many of the same measures of awareness and attitude as its two predecessors, it also included several new queries that assess the ability of respondents to recall specific news stories related to GM food, their interest in the topic, and where they would go to look for new information. Many questions that were repeated from previous years have changed considerably in the current survey. Some of the classic measures of awareness and opinion now incorporate an "unsure" response as choice supplied by the interviewer. While respondents were allowed to volunteer this response in the past, explicitly providing this option to respondents reduced guessing on knowledge-based questions and encouraged a more accurate representation of opinion than in the past. The report begins with an investigation of Americans' awareness and knowledge about the topic in general, their ability to recall related news stories, familiarity with laws and regulations as well as other questions designed to get at highly specific knowledge about agricultural biotechnology. Next, it details the effect of the new survey methodology on reported opinions about plant-based and animal-based GM food. Finally, it delves into a number of novel findings about interest in hypothetical television shows about GM food, desire for information on food labels, and reported behavior with regards to information seeking. Consistent with results from our previous studies and others, these findings suggest that the American public is generally unaware of GM food. Most Americans have heard or read little about it, are not aware of its prevalence in their lives, and are confused as to which type of GM products are available. Respondents struggled with factual questions related to GM food and the science behind it, could not recall news stories related to the topic, and were not very knowledgeable about laws regarding the labeling and testing of GM food. Americans are also unsure of their opinions about GM food and split in their assessments of the technology when forced to take a position. Americans say they are interested in the topic of GM food, specifically those topics related to human health. Respondents say they desire more information on food labels and report that they would like to see GM foods labeled as such. The majority of Americans admit they have never looked for information about GM food and most say they will search the Internet should the need arise.Research and Development/Tech Change/Emerging Technologies,

Monitoring the response to neoadjuvant hormone therapy for locally advanced breast cancer using three-dimensional time-resolved optical mammography.

Optical mammography is a functional imaging technique that uses near-infrared light to produce three-dimensional breast images of tissue oxygen saturation and hemoglobin concentration. It has been used to monitor the response to neoadjuvant chemotherapy in breast cancer patients. We present the first results on monitoring tumor response to hormone therapy using optical mammography. We present three case studies from postmenopausal women treated with neoadjuvant hormone therapy for locally advanced breast cancer. The women were scanned before starting treatment, once during treatment, and then before surgery. Changes in physiological and optical properties within the tumor and in the rest of the breast were evaluated. At the time of surgery, two patients partially responded to treatment and one did not respond. The patients that partially responded on ultrasound revealed a corresponding recovery to normal in the hemoglobin concentration images, whereas the nonresponder indicated an increase in hemoglobin concentration in the tumor compared to her pretreatment images. These case studies suggest that optical imaging of the breast during neoadjuvant hormone treatment can provide potentially valuable information, and that physiological changes within the tumor can be seen in response to treatment

A Mobile Health Lifestyle Program for Prevention of Weight Gain in Young Adults (TXT2BFiT): Nine-Month Outcomes of a Randomized Controlled Trial

BACKGROUND: The unprecedented rise in obesity among young adults, who have limited interaction with health services, has not been successfully abated. OBJECTIVE: The objective of this study was to assess the maintenance outcomes of a 12-week mHealth intervention on prevention of weight gain in young adults and lifestyle behaviors at 9 months from baseline. METHODS: A two-arm, parallel, randomized controlled trial (RCT) with subjects allocated to intervention or control 1:1 was conducted in a community setting in Greater Sydney, Australia. From November 2012 to July 2014, 18- to 35-year-old overweight individuals with a body mass index (BMI) of 25-31.99 kg/m2 and those with a BMI ≥ 23 kg/m2 and a self-reported weight gain of ≥ 2 kg in the past 12 months were recruited. A 12-week mHealth program "TXT2BFiT" was administered to the intervention arm. This included 5 coaching calls, 96 text messages, 12 emails, apps, and downloadable resources from the study website. Lifestyle behaviors addressed were intake of fruits, vegetables, sugar-sweetened beverages (SSBs), take-out meals, and physical activity. The control group received 1 phone call to introduce them to study procedures and 4 text messages over 12 weeks. After 12 weeks, the intervention arm received 2 further coaching calls, 6 text messages, and 6 emails with continued access to the study website during 6-month follow-up. Control arm received no further contact. The primary outcome was weight change (kg) with weight measured at baseline and at 12 weeks and self-report at baseline, 12 weeks, and 9 months. Secondary outcomes were change in physical activity (metabolic equivalent of task, MET-mins) and categories of intake for fruits, vegetables, SSBs, and take-out meals. These were assessed via Web-based surveys. RESULTS: Two hundred and fifty young adults enrolled in the RCT. Intervention participants weighed less at 12 weeks compared with controls (model β=-3.7, 95% CI -6.1 to -1.3) and after 9 months (model β=- 4.3, 95% CI - 6.9 to - 1.8). No differences in physical activity were found but all diet behaviors showed that the intervention group, compared with controls at 9 months, had greater odds of meeting recommendations for fruits (OR 3.83, 95% CI 2.10-6.99); for vegetables (OR 2.42, 95% CI 1.32-4.44); for SSB (OR 3.11, 95% CI 1.47-6.59); and for take-out meals (OR 1.88, 95% CI 1.07-3.30). CONCLUSIONS: Delivery of an mHealth intervention for prevention of weight gain resulted in modest weight loss at 12 weeks with further loss at 9 months in 18- to 35-year-olds. Although there was no evidence of change in physical activity, improvements in dietary behaviors occurred, and were maintained at 9 months. Owing to its scalable potential for widespread adoption, replication trials should be conducted in diverse populations of overweight young adults. TRIAL REGISTRATION: Australian and New Zealand Clinical Trials Registry (ANZCTR): ACTRN12612000924853; (Archived by WebCite at http://www.webcitation.org/6i6iRag55)