3,110 research outputs found
Adoptees Revisiting China
Since 1991, more than 80,000 children from China have been adopted to the United States. This thesis describes the circumstances that led to those adoptions and focuses on 17 Chinese adult adoptees’ return trip reculturation experiences. In doing so, this study reveals the impact of these trips on the transracial adoptees’ identities. Return trips significantly impacted adoptees with factors such as age during return trip, length of trip, linguistic fluency, and prior cultural knowledge greatly affecting trip experiences. Because of the ages of this cohort of adoptees, return trips may become more popular in the coming years as they enter adulthood, so this research will provide a lens to understand this form of reculturation for other Chinese adoptees embarking on this journey
SLC8 family of sodium/calcium exchangers (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
The sodium/calcium exchangers (NCX) use the extracellular sodium concentration to facilitate the extrusion of calcium out of the cell. Alongside the plasma membrane Ca2+-ATPase (PMCA) and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA), as well as the sodium/potassium/calcium exchangers (NKCX, SLC24 family), NCX allow recovery of intracellular calcium back to basal levels after cellular stimulation. When intracellular sodium ion levels rise, for example, following depolarisation, these transporters can operate in the reverse direction to allow calcium influx and sodium efflux, as an electrogenic mechanism. Structural modelling suggests the presence of 9 TM segments, with a large intracellular loop between the fifth and sixth TM segments
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