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21 research outputs found

Eculizumab improves fatigue in refractory generalized myasthenia gravis

Author: Acar N. P.
Agrawal B.
Agriesti J.
Ahn S. -H.
Akhter S.
Akiyama T.
Alam S.
AlbertiAguilo M. A.
Alboini P. E.
Alcon K.
Alsharabati M.
AlvesdeSiqueira Carvalho A.
Amamoto S.
AmaralAndrade A. C.
Amato A.
Amato K.
Ambrosio D.
Andersen H.
Anderson A.
Andoin A.
Annes M.
Antonini G.
Antozzi C.
Aranke S.
Arndt H.
Arnold T.
Arribas-Ibar E.
Asada S.
Assis N.
Aydinlik S.
Balkan B.
Barohn R.
Barroso F.
Becerikli G.
Beck K.
Bednarik J.
Bekircan-Kurt C. E.
Benatar M.
Berger A. R.
Bertorini T.
Bettini M.
Beydoun S.
BezerraRosa B.
Bhavaraju-Sanka R.
Bilsker M.
Bjarbo L.
Blackmore D.
Bodkin C.
Bonanno S.
Bravver E.
Brooks B.
Brown C.
Burdette M.
Butinhao C. F.
Caliskan Y.
Callison K.
Camera G.
Campanella A.
Carnes D.
Carrara F.
Carter C.
Casasnovas C.
Cash T.
CavalcanteLino V.
Cavus H.
Cesar P.
Chaudhry V.
Chaves M.
Chelnick S.
Chilingaryan A.
Chmelikova M.
Cho E. B.
Choi E. H.
Choi M. S.
Chopra M.
Cierny M.
Cochrane T.
Cooley A.
Corse A.
CortesVicente E.
Costabile T.
Cunningham S.
D&apos
D&apos
daCruz Pacheco D.
Daniels K.
daPenha AnaniasMorita M.
Darnell T.
daSilva L. A.
Davies D.
DeBleecker J.
deCassia Santos A.
deKoning K.
DeMey K.
Depreitere A.
deVisser M.
Dezsi L.
DiasBrockhausen I.
Diaz-Manera J.
Dicapua D.
DiezPorras L.
DiezTejedor E.
Dimachkie M.
Dimitriou A.
Dimitrova D.
DiPasquale A.
DiSanzo B.
Dishman L.
Distad J.
Doan V.
Dogan B.
Donahue C.
Downing S.
Droker B.
Duarte Silva L.
Duran G.
Echevarria L.
Efendi H.
Elsayed M.
Emmons K.
Engel M.
Eralinna J. -P.
Erdem-Ozdamar S.
Eriksson J.
Evoli A.
Fasanaro A.
Feder D.
Fernandes P.
Fernandez-Fournier M.
Ferreira L.
Fialho T. A. S.
Filla A.
Fionda L.
Fionda L.
Fondaw A.
Forshew D.
Frasca V.
Frasca V.
Freimer M.
Fujii Y.
Fukuda Y.
Funaka S.
Futono K.
Gabriele M.
Gamez J.
Garcia A. D.
Garcia R.
Garcia S.
Garibaldi M.
GhellerFriedrich M. A.
Giacomelli E.
Gibson T.
Gilchrist J.
Gili G.
Glenn M.
Golden L.
Gollogly J.
Gomes daSilva T. C.
Gomez Salcedo P.
GoncalvesGeraldo J.
Gong H.
Gonzalez A.
Gori M.
Goyal N.
Goyal N.
Guerreiro A.
Guingrich S.
Guptill J.
Gutmann L.
Gutmann L.
H. J. Ra
Haar L.
Hafer-Macko C.
Harbo T.
Harrison T.
Hart A.
Harvey B.
Hasuike T.
Hayashi T.
Hehir M.
Hendersen K.
Herbelin L.
Herbert C.
Hewlett J.
Hietala A.
Higuchi E.
Hisahara S.
Ho D.
Hobson-Webb L.
Hojgaard J.
Homedes-Pedret C.
Hong Y. -H.
Hopkins S.
Horvath M.
Howard J. F.
Hoyle J. C.
Huynh K.
Hwang E. B.
Hwang J. Y.
Illa I.
Imai T.
Inghilleri M.
Iorio R.
Ishiyama N.
Ishiyama Y.
Jacob S.
Jakab G.
Jara J.
Jeffery D.
Jenci N.
Jeong H. -N.
Jerath N.
Jingu M.
Johns K.
Jones F.
Jones H. J.
Juel V.
JuliaPalacios N.
Jung J. W.
Junkerova J.
Jurajdova I.
Kamakura S.
Kamegamori I.
Kanai T.
Kaneko Y.
Kang H. N.
Kanzaki A.
Karam C.
Karam C.
Karimi S.
Katz J.
Katzin L.
Kaur H.
Kawaguchi N.
Kawamata J.
Kawamura T.
Kazamel M.
Kelley A.
Keung B.
Khoury J.
Kikutake K.
Kim B.
Kim B. -J.
Kim B. J.
Kim M.
Kim S. M.
Kim Y. -H.
Kincaid J.
KirbasCavdar T.
Kissel J.
Kobashikawa T.
Kobayashi E.
Kobayashi H.
Koga M.
Koh D. Y.
Kohlrus S.
Konyane M.
Koo D. L.
Koo Y. S.
Kramer M.
Kressin N.
Krogh S.
Kumar A.
Kurihara R.
Kurkova B.
Kutlu A.
Kwan J.
Kwon J. Y.
Laaksonen M.
Lazaro A.
Lee C. N.
Lee H. L.
Lee H. S.
Lee J. E.
Lim J. -S.
Lin F.
Liu T.
Liu Y.
Locatelli A.
Locheke J.
Lokaitis B.
Loor J.
Lopergolo D.
LopezRuiz P.
Lovas G.
Lu L.
Lucy S.
Macagnan A. P.
Maeda Y.
Maggi L.
Mahdi-Rogers M.
Mahieu D.
Maier G.
Makamori M.
Malekniazi A.
Mallon A.
Mantegazza R.
Maqsood F.
Marano E.
Marburger T.
Marsili A.
MartineliTorres D. D.
MartinsRibeiro R.
Masaki K.
Massey J.
Mathew V.
Matolcsi J.
Matsuse D.
Matsushita T.
Mazia C. G.
Mazuela G.
McClain T.
McClain T.
McKenna K.
McKinnon J.
McKinnon N.
McVey A.
Meguro F.
Meherremova A.
Melo A. P.
Mercelis R.
Mezache L.
Micheels A.
Michon S. -C.
Miller R.
Min J. -H.
Minton B.
Miranda C.
Mitazaki T.
Miyawaki E.
Mizugami A.
Mogensen A.
Mohr H.
Mori M.
Morikawa M.
Morino S.
Mosmiller B.
Motomura M.
Mozaffar T.
Muharrem F.
Mukaino A.
Mumfrey-Thomas S.
Muppidi S.
Murahara T.
Murai H.
Nagane Y.
Nakamura Y.
Nance C.
Narayan J.
Narikawa K.
Nations S.
Naunton K.
Nemeth J.
NogueiraCoelho E.
Norwood F.
Noshiro M.
Novakova I.
Nowak R.
Nozaki K.
Nye J.
O&apos
Oksaranta O.
Okumura M.
Olalde H.
Onar M. K.
Onesti E.
Orsel G.
Osakada K.
OstergaardAutzen A.
Otavio MaiaGoncalves L.
Ozawa Y.
Ozcelik P.
Padilla P.
Paiva G.
Park S. A.
Pasanisi M.
Pascuzzi R.
Pasnoor M.
Patra K.
Patrick K.
Patwa H.
Paulose S.
Pazetto L. E.
Pedersen J.
PereiraMartins M.
Phan C.
Piehl F.
Pillai R.
Pineda C.
Pinto G.
Pinto W.
Pitha J.
Plevka S.
Pokala K.
Pol S.
Pozo M.
Prando N.
Pulley M.
Puorro G.
QuerolGutierrez L. A.
Reguliova K.
Renata CubasVolpe L.
Reyes E.
Rico G.
Robeson K.
Rocha R.
Roderus R.
Rodriguez deRivera F. J.
Roe K.
RojasGarcia R.
Rosenfeld J.
Roy G.
Rozsa C.
Rugiero M.
Saba J.
Sacca F.
Sadalage G.
Saito Y.
Saitoh M.
Sakamuri S.
Saklad A.
Salajegheh M.
Salvado M.
Samukawa M.
Sanjak M.
Sano Y.
SantosEngel M.
Sastre M.
Sathasivam S.
Sato M.
Sattar N.
Scala S.
Schommer C.
Schotte C.
Seddigh A.
Seelback J.
Semiz C.
Sen S.
Sengun I.
Seok H. Y.
Seok J.
Shabbir Y.
Shah A.
Shah A.
Shah J.
Sharma K.
Sheldon D.
Shimohama S.
Shimpo M.
Shin C. W.
Shin H. Y.
Shin M.
Shiraishi H.
Siddiqi Z.
Sieren J.
Silva M.
Silvestri N.
Smetcoren C.
Smith L.
Snook R.
Sohail F.
Sokratous G.
Souza BulleOliveira A.
Souza I.
SouzaDuca L.
Srinivasan J.
Statland J.
Steele J.
Stevens O.
Strom S.
Sune P.
Suzuki H.
Suzuki S.
Suzuki Y.
Swenson A.
Szabadosne B.
Szabo G.
Taichi N.
Takada K.
Takada M.
Takahashi M.
Takeyama R.
Tandan R.
Tano O.
Terzi M.
Tierney S.
Tilkin P.
TobonGonzales A.
Toncrova S.
Torane P.
Toska S.
Tran A.
Traub R.
Trivedi J.
Troili F.
Tsuda E.
Tsuda T.
Tsukita K.
Tsurumaru M.
Tuga C.
Tun O.
Tyblova M.
Uehara T.
Ugur M.
Utsugisawa K.
Uwasa K.
Uzawa A.
Van denAbeele G.
van derKooi A.
VanDaele S.
VanDamme P.
Vandenbussche N.
Vanderhook M.
Vanhee A.
Varga E.
Varghese M.
Vecsei L.
Veiga T.
VelezSantamaria V.
Ventura N.
Verjans S.
Veske A.
Vidal G.
Vidal N.
Vinge L.
Vissing J.
Vohanka S.
Vu H.
Vu T.
Vynckier J.
Vytopil M.
Wagemaekers L.
Waheed W.
Walsh M.
Wang J.
Wang J. J.
Watling D.
Watt E.
Weiner E.
Weiss M.
Welsh L.
Wheeler L.
Wilken M.
Witting N.
Wolfe G.
Wolfova M.
Woodall A.
Y. T. So
Yamamoto D.
Yamashita Y.
Yang I.
Yasuda I.
Yilmaz E.
Yoshida S.
Yoshimura S.
Young V.
Zakalik K.
Zapletalova O.
Zilliox L.
Publication venue: 'Springer Science and Business Media LLC'
Publication date: 01/01/2019
Field of study

Florence Research

Consistent improvement with eculizumab across muscle groups in myasthenia gravis

Author: Agrawal B.
Agriesti J.
Ahn S. -H.
Akhter S.
Akiyama T.
Alam S.
Alcon K.
Alsharabati M.
Alves de Siqueira Carvalho A.
Amamoto S.
Amaral de Andrade A. C.
Amato A.
Amato K.
Ambrosio D.
Andersen H.
Anderson A.
Annes M.
Antonia Alberti Aguilo M.
Antonini G.
Antonio Querol Gutierrez L.
Antozzi C.
Aranke S.
Ardoin A.
Arndt H.
Arnold T.
Arribas-Ibar E.
Asada S.
Assis N.
Augusto da Silva L.
Augusto Suriane Fialho T.
Aydinlik S.
Balkan B.
Barohn R.
Barroso F.
Becerikli G.
Beck K.
Bednarik J.
Bekircan-Kurt C.
Benatar M.
Bertorini T.
Bettini M.
Beydoun S.
Bezerra Rosa B.
Bhavaraju-Sanka R.
Bi Hwang E.
Bilsker M.
Bin Cho E.
Bjarbo L.
Blackmore D.
Bodkin C.
Bonanno S.
Bravver E.
Brooks B.
Brown C.
Burdette M.
Caliskan Y.
Callison K.
Camera G.
Campanella A.
Carnes D.
Carrara F.
Carter C.
Casasnovas C.
Cash T.
Cavalcante Lino V.
Cavus H.
Cesar P.
Chad Hoyle J.
Chaudhry V.
Chaves M.
Chelnick S.
Chilingaryan A.
Chmelikova M.
Choi M.
Chopra M.
Cierny M.
Cochrane T.
Cooley A.
Corse A.
Cortes Vicente E.
Costabile T.
Cunningham S.
D&apos
D&apos
da Cruz Pacheco D.
da Penha Ananias Morita M.
Dalila Garcia A.
Daniels K.
Darnell T.
Davies D.
De Bleecker J.
de Cassia Santos A.
de Koning K.
De Mey K.
de Visser M.
Depreitere A.
Dezsi L.
Di Pasquale A.
Dias Brockhausen I.
Diaz-Manera J.
Dicapua D.
Diez Porras L.
Diez Tejedor E.
Dimachkie M.
Dimitriou A.
Dimitrova D.
DiSanzo B.
Dishman L.
Distad J.
Doan V.
Dogan B.
Donahue C.
Downing S.
Droker B.
Duarte Silva L.
Duran G.
Echevarria L.
Eduardo Pazetto L.
Efendi H.
Elsayed M.
Emilio Alboini P.
Emmons K.
Engel M.
Eralinna J. -P.
Erdem-Ozdamar S.
Eriksson J.
Evoli A.
Fasanaro A.
Feder D.
Fernanda Butinhao C.
Fernandes P.
Fernandez-Fournier M.
Ferreira L.
Filla A.
Fionda L.
Fondaw A.
Forshew D.
Frasca V.
Freimer M.
Friedrich M. A. G.
Fujii Y.
Fukuda Y.
Funaka S.
Futono K.
Gabriel Mazia C.
Gabriele M.
Gamez Carbonell J.
Garcia R.
Garcia S.
Garibaldi M.
Giacomelli E.
Gibson T.
Gilchrist J.
Gili G.
Glenn M.
Golden L.
Gollogly J.
Gomes da Silva T. C.
Gomez Salcedo P.
Goncalves Geraldo J.
Goncalves L. O. M.
Gong H.
Gonzalez A.
Gori M.
Goyal N.
Goyal N.
Guerreiro A.
Guingrich S.
Guptill J.
Gutmann L.
Gutmann L.
Haar L.
Hafer-Macko C.
Harbo T.
Harrison T.
Hart A.
Harvey B.
Hasuike T.
Haw Choi E.
Hayashi T.
Hehir M.
Henderson K.
Herbelin L.
Herbert C.
Hewlett J.
Hietala A.
Higuchi E.
Hisahara S.
Ho D.
Hobson-Webb L.
Hojgaard J.
Homedes-Pedret C.
Hong Y. -H.
Hopkins S.
Horvath M.
Howard J. F.
Huynh K.
Illa I.
Imai T.
Inghilleri M.
Iorio R.
Ishiyama N.
Ishiyama Y.
Jacob S.
Jakab G.
James Jones H.
Jara J.
Jeffery D.
Jenci N.
Jeong H. -N.
Jerath N.
Jingu M.
Johns K.
Jones F.
Joon Kim B.
Juel V.
Julia Palacios N.
Jung J.
Junkerova J.
Jurajdova I.
Kamakura S.
Kamegamori I.
Kanai T.
Kaneko Y.
Kanzaki A.
Karam C.
Karimi S.
Katz J.
Katzin L.
Kaur H.
Kawaguchi N.
Kawamata J.
Kawamura T.
Kazamel M.
Kazim Onar M.
Kelley A.
Keung B.
Khoury J.
Kikutake K.
Kim B.
Kim B. -J.
Kim M.
Kim Y. -H.
Kincaid J.
Kirbas Cavdar T.
Kissel J.
Kobashikawa T.
Kobayashi E.
Kobayashi H.
Koga M.
Koh D. Y.
Kohlrus S.
Konyane M.
Kramer M.
Kressin N.
Krogh S.
Kumar A.
Kurihara R.
Kurkova B.
Kutlu A.
Kwan J.
Kwon J.
Laaksonen M.
Lazaro A.
Lee H.
Lee J.
Lim Koo D.
Lim J. -S.
Lin F.
Liu T.
Liu Y.
Locatelli A.
Locheke J.
Lokaitis B.
Loor J.
Lopergolo D.
Lopez Ruiz P.
Lovas G.
Lu L.
Lucy S.
Maeda Y.
Maggi L.
Mahdi-Rogers M.
Mahieu D.
Maier G.
Malekniazi A.
Mallon A.
Mantegazza R.
Maqsood F.
Marano E.
Marburger T.
Marsili A.
Martins Ribeiro R.
Masaki K.
Massey J.
Mathew V.
Matolcsi J.
Matsuse D.
Matsushita T.
Mazuela G.
McClain T.
McKenna K.
McKinnon J.
McKinnon N.
McVey A.
Meguro F.
Meherremova A.
Mercelis R.
Mette Ostergaard Autzen A.
Mezache L.
Micheels A.
Michon S. -C.
Miller R.
Min Kim S.
Min J. -H.
Minton B.
Miranda C.
Miyawaki E.
Miyazaki T.
Mizugami A.
Mogensen A.
Mohr H.
Mori M.
Morikawa M.
Morino S.
Mosmiller B.
Motomura M.
Mozaffar T.
Muharrem F.
Mukaino A.
Mumfrey-Thomas S.
Muppidi S.
Murahara T.
Murai H.
Nagane Y.
Nakamori M.
Nakamura Y.
Nam Kang H.
Nance C.
Narayan J.
Narikawa K.
Nations S.
Naunton K.
Nemeth J.
Nogueira Coelho E.
Norwood F.
Noshiro M.
Novakova I.
Nowak R.
Nozaki K.
Nye J.
Nyoung Lee C.
O&apos
Oksaranta O.
Okumura M.
Olalde H.
Onesti E.
Orsel G.
Osakada K.
Ozawa Y.
Ozcelik P.
Padilla P.
Paiva G.
Park S.
Pasanisi M.
Pascuzzi R.
Pasnoor M.
Pasquale A.
Patrick K.
Patwa H.
Paula Macagnan A.
Paula Melo A.
Paulose S.
Pedersen J.
Pereira Martins M.
Phan C.
Piehl F.
Pillai R.
Pinar Acar N.
Pineda C.
Pinto G.
Pinto W.
Pitha J.
Plevka S.
Pol S.
Polaka K.
Pozo M.
Prando N.
Pulley M.
Puorro G.
Ra H.
Reguliova K.
Renata Cubas Volpe L.
Reyes E.
Rico G.
Robeson K.
Rocha R.
Roderus R.
Rodriguez de Rivera F. J.
Roe K.
Rojas Garcia R.
Rosenfeld J.
Ross Berger A.
Roy G.
Rozsa C.
Rugiero M.
Saba J.
Sacca F.
Sadalage G.
Saito Y.
Saitoh M.
Sakamuri S.
Saklad A.
Salajegheh M.
Salvado Figueras M.
Samukawa M.
Sanjak M.
Sano Y.
Santos Engel M.
Sastre M.
Sathasivam S.
Sato M.
Sattar N.
Scala S.
Schommer C.
Schotte C.
Scott T.
Seddigh A.
Seelbach J.
Semiz C.
Sen S.
Sengun I.
Seo Koo Y.
Seok Lee H.
Seok J.
Shabbir Y.
Shah A.
Shah A.
Shah J.
Sharma K.
Sheldon D.
Shimohama S.
Shimpo M.
Shin M.
Shiraishi H.
Siddiqi Z.
Sieren J.
Silva M.
Silvestri N.
Smetcoren C.
Smith L.
Snook R.
Sohail F.
Sokratous G.
Souza Bulle Oliveira A.
Souza Duca L.
Souza I.
Srinivasan J.
Statland J.
Steele J.
Stevens O.
Strom S.
Sune P.
Suzuki H.
Suzuki S.
Suzuki Y.
Swenson A.
Szabadosne B.
Szabo G.
Taichi N.
Takada K.
Takada M.
Takahashi M.
Takeyama R.
Tandan R.
Tano O.
Terzi M.
Tilkin P.
Tobon Gonzalez A.
Toncrova S.
Torane P.
Torres D. D. M.
Toska S.
Tran A.
Traub R.
Trivedi J.
Troili F.
Tsuda E.
Tsuda T.
Tsukita K.
Tsurumaru M.
Tuga C.
Tun O.
Tyblova M.
Uehara T.
Ugur M.
Utsugisawa K.
Uwasa K.
Uzawa A.
Van Daele S.
Van Damme P.
Van den Abeele G.
van der Kooi A.
Vandenbussche N.
Vanderhook M.
Vanhee A.
Varga E.
Varghese M.
Vecsei L.
Veiga T.
Velez Santamaria V.
Ventura N.
Verjans S.
Veske A.
Vidal G.
Vidal N.
Vinge L.
Vissing J.
Vohanka S.
Vu H.
Vu T.
Vynckier J.
Vytopil M.
Wagemaekers L.
Waheed W.
Walsh M.
Wang Y.
Watling D.
Watt E.
Weiner E.
Weiss M.
Welsh L.
Wheeler L.
Wilken M.
Witting N.
Wolfe G.
Wolfova M.
Won Shin C.
Woodall A.
Y. T. So
Yamamoto D.
Yamashita Y.
Yang I.
Yasuda I.
Ye Hwang J.
Yilmaz E.
Yoshida S.
Yoshimura S.
Youl Seok H.
Young Shin H.
Young V.
Yountz M.
Zakalik K.
Zapletalova O.
Zilliox L.
Publication venue: 'Wiley'
Publication date: 01/01/2020
Field of study

Florence Research

Post-intervention Status in Patients With Refractory Myasthenia Gravis Treated With Eculizumab During REGAIN and Its Open-Label Extension

Author: Acary Souza Bulle Oliveira
Adam Hart
Adife Veske
Aditya Kumar
Aikaterini Dimitriou
Akihiro Mukaino
Akiko Kanzaki
Akiyuki Uzawa
Akshay Shah
Alan Ross Berger
Albert Hietala
Alberta Locatelli
Alejandra Dalila Garcia
Alejandro Tobon Gonzalez
Alessandro Filla
Alex Fondaw
Alexandre Guerreiro
Alexandre Guerreiro
Ali Malekniazi
Aline de Cassia Santos
Alzira Alves de Siqueira Carvalho
Amaiak Chilingaryan
Amanda Anderson
Amelia Evoli
Amna Shah
Amy Saklad
Amy Woodall
Ana Carolina Amaral de Andrade
Ana Lazaro
Ana Paula Macagnan
Ana Paula Melo
Andrea Corse
Andrea Kelley
Andrea Swenson
Angela Ardoin
Angela Campanella
Angela Marsili
Angela Micheels
Angiola Fasanaro
Anh Tran
Anita Mogensen
Ann D'Hont
Anna Gonzalez
Anne Cooley
Anne Mette Ostergaard Autzen
Anneke van der Kooi
Annelies Depreitere
Annelies Vanhee
Anthony Amato
Antonella Di Pasquale
Antonella Di Pasquale
April McVey
Arshira Seddigh
Arzu Meherremova
Ashley Mallon
Aya Mizugami
Ayse Kutlu
Baki Dogan
Barbara Lokaitis
Barbora Kurkova
Bengu Balkan
Benison Keung
Benjamin Brooks
Beth DiSanzo
Betsy Mosmiller
Booth H. D. E.
Brajesh Agrawal
Brian Droker
Brian Minton
Brigitta Szabadosne
Brittany Harvey
Bruno Bezerra Rosa
Bryan Kim
Byoung Joon Kim
Byung-Jo Kim
Can Ebru Bekircan-Kurt
Cansu Semiz
Carlo Antozzi
Carlos Casasnovas
Carol Herbert
Carolina Miranda
Caroline Schotte
Cecile Phan
Celal Tuga
Chae Won Shin
Chafic Karam
Chafic Karam
Chang Nyoung Lee
Charlene Hafer-Macko
Charlotte Smetcoren
Christian Homedes-Pedret
Christopher Nance
Claire Brown
Clara Schommer
Claudio Gabriel Mazia
Colleen Pineda
Craig Donahue
Cristiani Fernanda Butinhao
Csilla Rozsa
Cynthia Bodkin
Cynthia Carter
Da Yoon Koh
Dae Lim Koo
Dai Matsuse
Daiane da Cruz Pacheco
Daisuke Yamamoto
Dallas Forshew
Daniel Ambrosio
Daniel Dicapua
Danielle Sheldon
Dave Watling
David Feder
Debbie Davies
Debora Dada Martineli Torres
Dennis Jeffery
Derrick Blackmore
Diana Dimitrova
Diego Lopergolo
Donna Carnes
Doreen Ho
Délphine Mahieu
Edina Varga
Elaine Weiner
Elena Bravver
Elena Cortes Vicente
Elena Giacomelli
Eliana Reyes
Elisabet Arribas-Ibar
Elizabeth Watt
Emanuela Onesti
Emiko Tsuda
Enrico Marano
Eri Kobayashi
Erica Nogueira Coelho
Eriko Higuchi
Eriko Miyawaki
Eun Bi Hwang
Eun Bin Cho
Eun Haw Choi
Exuperio Diez Tejedor
Ezgi Yilmaz
Fabio Barroso
Faisal Sohail
Fatima Maqsood
Fernanda Carrara
Fernanda Troili
Filiz Muharrem
Fiona Norwood
Floyd Jones
Francesco Saccà
Francisco Javier Rodriguez de Rivera
Frank Lin
Fredrik Piehl
Fujita K. P.
Fumie Meguro
Gabor Lovas
Gabor Lovasamela César
Gabriel Paiva
Gabrielle Rico
Gal Maier
Gedeonne Jakab
Gedeonne Jakab
Giannis Sokratous
Giorgia Camera
Giorgia Puorro
Giovanni Antonini
Girija Sadalage
Gisela Gili
Gonzalo Mazuela
Gonzalo Vidal
Graziela Pinto
Gulmohor Roy
Gulsah Becerikli
Gulsah Orsel
Gustavo Duran
Guy Van den Abeele
Gyorgyi Szabo
H James Jones
Ha Young Shin
Ha-Neul Jeong
Hakan Cavus
Harpreet Kaur
Heena Olalde
Heike Arndt
Henning Andersen
Henrique Mohr
Hidekazu Suzuki
Hirokazu Shiraishi
Hiroyuki Murai
Hisako Kobayashi
Hong Vu
Hoo Nam Kang
Howard J. F.
Hui Gong
Huned Patwa
Hung Youl Seok
Husnu Efendi
HyeJin Ra
HyeLim Lee
Hyung Seok Lee
Iandra Souza
Igor Dias Brockhausen
Ihsan Sengun
Ikuko Kamegamori
Ikuko Yasuda
Irene Yang
Isabel Illa
Ivana Jurajdova
Iveta Novakova
Jaana Eriksson
Jae-Sung Lim
Jaimin Shah
Jakit Gollogly
James Gilchrist
Jan De Bleecker
Jan Vynckier
Jana Junkerova
Jane Distad
Jane Pedersen
Janice Massey
Jasmine Hewlett
Jaya Trivedi
Jayashri Srinivasan
Jeffery Statland
Jeffrey Guptill
Jeffrey Narayan
Jeffrey Rosenfeld
Jenna Seelbach
Jeri Sieren
Jerry Locheke
Ji Ye Hwang
JiEun Lee
Jinmyoung Seok
JinWoo Jung
Jiri Pitha
Joan Højgaard
Joan Nye
Joanne Nemeth
John Kincaid
John Kissel
John Loor
John Vissing
Jonathan Katz
Jonathan McKinnon
Jordan Jara
Jordana Gonçalves Geraldo
Jordi Diaz-Manera
Josef Bednarik
Josep Gamez Carbonell
Joseph Chad Hoyle
Ju-Hong Min
Judit Matolcsi
Juha-Pekka Erälinna
Julie Agriesti
Julie Khoury
Julie Steele
Juliet Saba
Jun Kawamata
Justin Kwan
JuYoung Kwon
Kaitlyn McKenna
Kaori Osakada
Kaori Uwasa
Kara Patrick
Karan Alcon
Karen Callison
Karen Zakalik
Katarina Reguliova
Kate Beck
Katherine Amato
Kathryn Johns
Kathy de Koning
Katrien De Mey
Katsuhisa Masaki
Kazumi Futono
Kazumi Takada
Keiko Kikutake
Kelley Emmons
Kendrick Henderson
Kenichi Tsukita
Kenkichi Nozaki
Kerry Naunton
Kevin Daniels
Khema Sharma
Kimberly Robeson
Kimiaki Utsugisawa
Koichi Narikawa
Krishna Polaka
Kristen Roe
Kristin Huynh
Lara Katzin
Laszlo Vecsei
Laura Diez Porras
Laura Echevarria
Laura Fionda
Laura Fionda
Laura Golden
Laura Haar
Laura Herbelin
Lauren Wheeler
Laurie Gutmann
Lena Bjarbo
Lesly Welsh
Liang Lu
Liene Duarte Silva
Linda Wagemaekers
Lindsay Zilliox
Lisa Hobson-Webb
Lisa Smith
Livia Dezsi
Lorenzo Maggi
Lorraine Dishman
Lotte Vinge
Louisa Mezache
Lucas Eduardo Pazetto
Luciana Ferreira
Luciana Renata Cubas Volpe
Luciana Souza Duca
Ludwig Gutmann
Luis Antonio Querol Gutiérrez
Luiz Augusto da Silva
Luiz Otavio Maia Gonçalves
Maeda Yasuko
Magda Chmelikova
Maki Jingu
Makoto Samukawa
Mamatha Pasnoor
Manisha Chopra
Mantegazza R.
Marcela Silva
Marcela Wolfova
Marcelo Annes
Marcelo Chaves
Marcelo Rugiero
Marek Cierny
Marguerite Engel
Maria Antonia Alberti Aguilo
Maria da Penha Ananias Morita
Maria Gabriele
Maria Gori
Maria Pasanisi
Maria Salvado Figueras
Maria Sastre
Marianne de Visser
Mariela Bettini
Marina Pozo
Martin Bilsker
Mary Varghese
Maryanne Burdette
Masahiro Mori
Masakatsu Motomura
Masaki Saitoh
Masako Tsurumaru
Masanori Takahashi
Masayuki Nakamori
Matteo Garibaldi
Maureen Walsh
Maurer Pereira Martins
Maurizio Inghilleri
Maurício AndréGheller Friedrich
Mayuko Noshiro
Mazen Dimachkie
Megan Kramer
Megumi Koga
Meinoshin Okumura
Melanie Glenn
Melinda Horvath
Michael Benatar
Michael Hehir
Michael Pulley
Michael Weiss
Michaela Tyblova
Michal Vytopil
Miguel Wilken
Mihoko Takada
Miju Shin
Mikko Laaksonen
Mireya Fernandez-Fournier
Mireya Fernandez-Fournier
Miri Kim
Miriam Freimer
Misa Shimpo
MiSong Choi
Miwako Sato
Miyuki Morikawa
Mohamed Kazamel
Mohamed Mahdi-Rogers
Mohammad Alsharabati
Mohammed Salajegheh
Mohammed Sanjak
Mollie Vanderhook
Mona Elsayed
Monika Konyane
Muppidi S.
Murat Terzi
Murilo Santos Engel
Musa Kazim Onar
Muzeyyen Ugur
Nadia Sattar
Namie Taichi
Namita Goyal
Nanna Witting
Naoki Kawaguchi
Naoko Ishiyama
Natalia Julia Palacios
Natalia Prando
Natália Assis
Naya McKinnon
Nazire Pinar Acar
Neelam Goyal
Nicholas Silvestri
Nicholas Ventura
Nicolas Vandenbussche
Nicole Jenci
Nicole Kressin
Nivedita Jerath
Nuria Vidal
O'Brien F. L.
Ohito Tano
Olga Zapletalova
Olivier Stevens
Olli Oksaranta
Ozlem Tun
Paolo Emilio Alboini
Patricia Padilla
Patrícia Fernandes
Pedro Lopez Ruiz
Petra Tilkin
Philip Van Damme
Pilar Gomez Salcedo
Pilar Sune
Pinar Ozcelik
Pravin Torane
Pravin Torane
Raffaele Iorio
Ratna Bhavaraju-Sanka
Rebecca Traub
Rebekah Garcia
Rekha Pillai
Renata Martins Ribeiro
Ricardo Rojas Garcia
Richard Barohn
Richard Nowak
Rikako Kurihara
Rikki Roderus
Riley Snook
Robert Miller
Robert Pascuzzi
Rosana Rocha
Rudy Mercelis
Rumi Takeyama
Rup Tandan
Sabrina Pol
Sachiko Kamakura
Said Beydoun
Saiju Jacob
Salma Akhter
Sanaz Karimi
Sandi Mumfrey-Thomas
Sandra Guingrich
SangAe Park
Sara-Claude Michon
Sarada Sakamuri
Sarah Plevka
Sarah Verjans
Scott Cunningham
Seda Aydinlik
Sedat Sen
Seiko Yoshida
Seung Min Kim
Sevim Erdem-Ozdamar
Shachie Aranke
Shannon Lucy
Sharmeen Alam
Sharon Chelnick
Sharon Downing
Sharon Nations
Shin Hisahara
Shirley Paulose
Shirli Toska
Shizuka Asada
Shoko Amamoto
Shuichiro Suzuki
Shun Shimohama
Shun Shimohama
Shunsuke Yoshimura
Sien Van Daele
Silvia Bonanno
Sivakumar Sathasivam
So-Hyun Ahn
Soichiro Funaka
Sonia Garcia
Stanislav Vohanka
Stanislava Toncrova
Stefania Morino
Stephanie Kohlrus
Stephanie Scala
Steve Hopkins
Susan Strom
Susanne Krogh
Tahseen Mozaffar
Taira Uehara
Takashi Hayashi
Takashi Murahara
Takuya Matsushita
Tamar Gibson
Tamires Cristina Gomes da Silva
Taylor Darnell
Teiichiro Miyazaki
Teresa Costabile
Terry McClain
Terry McClain
Tessa Marburger
Tetsuya Akiyama
Tetsuya Kanai
Thabata Veiga
Thomas Arnold
Thomas Cochrane
Thomas Harbo
Tierney Scott
Tina Liu
Tiyonnoh Cash
Tomihiro Imai
Tomihiro Imai
Tomohiro Kawamura
Tomoko Tsuda
Tomomi Kobashikawa
Tomoya Hasuike
Tomás Augusto Suriane Fialho
Tuan Vu
Tugce Kirbas Cavdar
Tulio Bertorini
Tuula Harrison
Valentina D'Amato
Valentina Velez Santamaria
Valeria Cavalcante Lino
Valerie Young
Veena Mathew
Vern Juel
Victor Doan
Vinay Chaudhry
Vittorio Frasca
Vittorio Frasca
Waqar Waheed
Wiendl H.
Wladimir Pinto
Wolfe G. I.
Yagmur Caliskan
Yasmeen Shabbir
Yasmeen Shabbir
Yasushi Suzuki
Ye Liu
Yoko Ishiyama
Yoko Kaneko
Yong Seo Koo
Yool-Hee Kim
Yoon-Ho Hong
Yoshiko Sano
Yuen T So
Yuka Saito
Yukiko Ozawa
Yuko Fujii
Yumi Yamashita
Yumiko Nakamura
Yunxia Wang
Yuriko Nagane
Yusuke Fukuda
Zaeem Siddiqi
Publication venue: 'Ovid Technologies (Wolters Kluwer Health)'
Publication date: 01/01/2021
Field of study

OBJECTIVE: To evaluate whether eculizumab helps patients with anti-acetylcholine receptor-positive (AChR+) refractory generalized myasthenia gravis (gMG) achieve the Myasthenia Gravis Foundation of America (MGFA) post-intervention status of minimal manifestations (MM), we assessed patients' status throughout REGAIN (Safety and Efficacy of Eculizumab in AChR+ Refractory Generalized Myasthenia Gravis) and its open-label extension. METHODS: Patients who completed the REGAIN randomized controlled trial and continued into the open-label extension were included in this tertiary endpoint analysis. Patients were assessed for the MGFA post-intervention status of improved, unchanged, worse, MM, and pharmacologic remission at defined time points during REGAIN and through week 130 of the open-label study. RESULTS: A total of 117 patients completed REGAIN and continued into the open-label study (eculizumab/eculizumab: 56; placebo/eculizumab: 61). At week 26 of REGAIN, more eculizumab-treated patients than placebo-treated patients achieved a status of improved (60.7% vs 41.7%) or MM (25.0% vs 13.3%; common OR: 2.3; 95% CI: 1.1-4.5). After 130 weeks of eculizumab treatment, 88.0% of patients achieved improved status and 57.3% of patients achieved MM status. The safety profile of eculizumab was consistent with its known profile and no new safety signals were detected. CONCLUSION: Eculizumab led to rapid and sustained achievement of MM in patients with AChR+ refractory gMG. These findings support the use of eculizumab in this previously difficult-to-treat patient population. CLINICALTRIALSGOV IDENTIFIER: REGAIN, NCT01997229; REGAIN open-label extension, NCT02301624. CLASSIFICATION OF EVIDENCE: This study provides Class II evidence that, after 26 weeks of eculizumab treatment, 25.0% of adults with AChR+ refractory gMG achieved MM, compared with 13.3% who received placebo

Archivio della ricerca- Università di Roma La Sapienza

Minimal Symptom Expression' in Patients With Acetylcholine Receptor Antibody-Positive Refractory Generalized Myasthenia Gravis Treated With Eculizumab

Author: Agrawal Brajesh
Agriesti Julie
Ahn So-Hyun
Akhter Salma
Akiyama Tetsuya
Alam Sharmeen
Alcon Karan
Alsharabati Mohammad
Alves de Siqueira Carvalho Alzira
Amamoto Shoko
Amato Anthony
Amato Katherine
Ambrosio Daniel
Andersen Henning
Anderson Amanda
Andoin Angela
André Gheller Friedrich Maurício
Annes Marcelo
Antonia Alberti Aguilo Maria
Antonini Giovanni
Antonio Querol Gutiérrez Luis
Antozzi Carlo
Aranke Shachie
Arndt Heike
Arnold Thomas
Arribas-Ibar Elisabet
Asada Shizuka
Assis Natália
Augusto da Silva Luiz
Augusto Suriane Fialho Tomás
Aydinlik Seda
Balkan Bengu
Barohn Richard
Barroso Fabio
Becerikli Gulsah
Beck Kate
Bednarik Josef
Benatar Michael
Bertorini Tulio
Bettini Mariela
Beydoun Said
Bezerra Rosa Bruno
Bhavaraju-Sanka Ratna
Bi Hwang Eun
Bilsker Martin
Bin Cho Eun
Bjarbo Lena
Blackmore Derrick
Bodkin Cynthia
Bonanno Silvia
Bravver Elena
Brooks Benjamin
Brown Claire
Burdette Maryanne
Caliskan Yagmur
Callison Karen
Camera Giorgia
Campanella Angela
Carnes Donna
Carolina Amaral de Andrade Ana
Carrara Fernanda
Carter Cynthia
Casasnovas Carlos
Cash Tiyonnoh
Cavalcante Lino Valeria
Cavus Hakan
Chad Hoyle Joseph
Chaudhry Vinay
Chaves Marcelo
Chelnick Sharon
Chilingaryan Amaiak
Chmelikova Magda
Choi MiSong
Chopra Manisha
Cierny Marek
Cochrane Thomas
Cooley Anne
Corse Andrea
Cortes Vicente Elena
Costabile Teresa
Cristina Gomes da Silva Tamires
Cunningham Scott
César Pamela
D'Amato Valentina
D'Hont Ann
da Cruz Pacheco Daiane
da Penha Ananias Morita Maria
Dada Martineli Torres Debora
Dalila Garcia Alejandra
Daniels Kevin
Darnell Taylor
Davies Debbie
De Bleecker Jan
de Cassia Santos Aline
de Koning Kathy
De Mey Katrien
de Visser Marianne
Depreitere Annelies
Dezsi Livia
Di Pasquale Antonella
Dias Brockhausen Igor
Diaz-Manera Jordi
Dicapua Daniel
Diez Porras Laura
Diez Tejedor Exuperio
Dimachkie Mazen
Dimitriou Aikaterini
Dimitrova Diana
DiSanzo Beth
Dishman Lorraine
Distad Jane
Doan Victor
Dogan Baki
Donahue Craig
Downing Sharon
Droker Brian
Duarte Silva Liene
Duran Gustavo
Ebru Bekircan-Kurt Can
Echevarria Laura
Eduardo Pazetto Lucas
Efendi Husnu
Elsayed Mona
Emilio Alboini Paolo
Emmons Kelley
Engel Marguerite
Erdem-Ozdamar Sevim
Eriksson Jaana
Erälinna Juha-Pekka
Evoli Amelia
Fasanaro Angiola
Feder David
Fernanda Butinhao Cristiani
Fernandes Patrícia
Fernandez-Fournier Mireya
Fernandez-Fournier Mireya
Ferreira Luciana
Filla Alessandro
Fionda Laura
Fionda Laura
Fondaw Alex
Forshew Dallas
Frasca Vittorio
Frasca Vittorio
Freimer Miriam
Fujii Yuko
Fukuda Yusuke
Funaka Soichiro
Futono Kazumi
Gabriel Mazia Claudio
Gabriele Maria
Gamez Carbonell Josep
Garcia Rebekah
Garcia Sonia
Garibaldi Matteo
Giacomelli Elena
Gibson Tamar
Gilchrist James
Gili Gisela
Glenn Melanie
Golden Laura
Gollogly Jakit
Gomez Salcedo Pilar
Gong Hui
Gonzalez Anna
Gonçalves Geraldo Jordana
Gori Maria Cristina
Goyal Namita
Goyal Neelam
Guerreiro Alexandre
Guinrich Sandra
Guptill Jeffrey
Gutmann Laurie
Gutmann Ludwig
Haar Laura
Hafer-Macko Charlene
Harbo Thomas
Harrison Tuula
Hart Adam
Harvey Brittany
Hasuike Tomoya
Haw Choi Eun
Hayashi Takashi
Hehir Michael
Henderson Kendrick
Herbelin Laura
Herbert Carol
Hewlett Jasmine
Hietala Albert
Higuchi Eriko
Hisahara Shin
Ho Doreen
Hobson-Webb Lisa
Homedes-Pedret Christian
Hong Yoon-Ho
Hopkins Steve
Horvath Melinda
Howard Jr James
Huynh Kristin
Højgaard Joan
Illa Isabel
Imai Tomihiro
Imai Tomihiro
Inghilleri Maurizio
Iorio Raffaele
Ishiyama Naoko
Ishiyama Yoko
Jacob Saiju
Jakab Gedeonne
James Jones H
Jara Jordan
Javier Rodriguez de Rivera Francisco
Jeffery Dennis
Jenci Nicole
Jeong Ha-Neul
Jerath Nivedita
Jingu Maki
Johns Kathryn
Jones Floyd
Joon Kim Byoung
Juel Vern
Julia Palacios Natalia
Jung JinWoo
Junkerova Barbora Kurkova Jana
Jurajdova Ivana
Kamakura Sachiko
Kamegamori Ikuko
Kanai Tetsuya
Kaneko Yoko
Kanzaki Akiko
Karam Chafic
Karam Chafic
Karimi Sanaz
Katz Jonathan
Katzin Lara
Kaur Harpreet
Kawaguchi Naoki
Kawamata Jun
Kawamura Tomohiro
Kazamel Mohamed
Kazim Onar Musa
Kelley Andrea
Keung Benison
Khoury Julie
Kikutake Keiko
Kim Bryan
Kim Byung-Jo
Kim Miri
Kim Yool-Hee
Kincaid John
Kirbas Cavdar Tugce
Kissel John
Kobashikawa Tomomi
Kobayashi Eri
Kobayashi Hisako
Koga Megumi
Kohlrus Stephanie
Konyane Monika
Kramer Megan
Kressin Nicole
Krogh Susanne
Kumar Aditya
Kurihara Rikako
Kutlu Ayse
Kwan Justin
Kwon JuYoung
Laaksonen Mikko
Lazaro Ana
Lee HyeLim
Lee JiEun
Lim Koo Dae
Lim Jae-Sung
Lin Frank
Liu Tina
Liu Ye
Locatelli Alberta
Locheke Jerry
Lokaitis Barbara
Loor John
Lopergolo Diego
Lopez Ruiz Pedro
Lovas Gabor
Lu Liang
Lucy Shannon
Maeda Yasuko
Maggi Lorenzo
Mahdi-Rogers Mohamed
Mahieu Délphine
Maier Gal
Makamori Masayuki
Malekniazi Ali
Mallon Ashley
Mantegazza Renato
Maqsood Fatima
Marano Enrico
Marburger Tessa
Marsili Angela
Martins Ribeiro Renata
Masaki Katsuhisa
Massey Janice
Mathew Veena
Matolcsi Judit
Matsuse Dai
Matsushita Takuya
Mazuela Gonzalo
McClain Terry
McClain Terry
McKenna Kaitlyn
McKinnon Jonathan
McKinnon Naya
McVey April
Meguro Fumie
Meherremova Arzu
Mercelis Rudy
Mette Ostergaard Autzen Anne
Mezache Louisa
Micheels Angela
Michon Sara-Claude
Miller Robert
Min Kim Seung
Min Ju-Hong
Minton Brian
Miranda Carolina
Mitazaki Teiichiro
Miyawaki Eriko
Mizugami Aya
Mogensen Anita
Mohr Henrique
Mori Masahiro
Morikawa Miyuki
Morino Stefania
Mosmiller Betsy
Motomura Masakatsu
Mozaffar Tahseen
Muharrem Filiz
Mukaino Akihiro
Mumfrey-Thomas Sandi
Muppidi Srikanth
Murahara Takashi
Murai Hiroyuki
Nagane Yuriko
Nakamura Yumiko
Nam Kang Hoo
Nance Christopher
Narayan Jeffrey
Narikawa Koichi
Nations Sharon
Naunton Kerry
Nemeth Joanne
Nogueira Coelho Erica
Norwood Fiona
Noshiro Mayuko
Novakova Iveta
Nowak Richard
Nozaki Kenkichi
Nye Joan
Nyoung Lee Chang
Oksaranta Olli
Okumura Meinoshin
Olalde Heena
Onesti Emanuela
Orsel Gulsah
Osakada Kaori
Otavio Maia Gonçalves Luiz
Ozawa Yukiko
Ozcelik Pinar
Padilla Patricia
Paiva Gabriel
Park SangAe
Pasanisi Maria
Pascuzzi Robert
Pasnoor Mamatha
Patrick Kara
Patwa Huned
Paula Macagnan Ana
Paula Melo Ana
Paulose Shirley
Pedersen Jane
Pereira Martins Maurer
Phan Cecile
Piehl Fredrik
Pillai Rekha
Pinar Acar Nazire
Pineda Colleen
Pinto Graziela
Pinto Wladimir
Pitha Jiri
Plevka Sarah
Pol Sabrina
Polaka Krishna
Pozo Marina
Prando Natalia
Previous
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Pulley Michael
Puorro Giorgia
Ra HyeJin
Reguliova Katarina
Renata Cubas Volpe Luciana
Reyes Eliana
Rico Gabrielle
Robeson Kimberly
Rocha Rosana
Roderus Rikki
Roe Kristen
Rojas Garcia Ricardo
Rosenfeld Jeffrey
Ross Berger Alan
Roy Gulmohor
Rozsa Csilla
Rugiero Marcelo
Saba Juliet
Saccà Francesco
Sadalage Girija
Saito Yuka
Saitoh Masaki
Sakamuri Sarada
Saklad Amy
Salajegheh Mohammed
Salvado Figueras Maria
Samukawa Makoto
Sanjak Mohammad
Sanjak Mohammed
Sano Yoshiko
Santos Engel Murilo
Sastre Maria
Sathasivam Sivakumar
Sato Miwako
Sattar Nadia
Scala Stephanie
Schommer Clara
Schotte Caroline
Seddigh Arshira
Seelbach Jenna
Semiz Cansu
Sen Sedat
Sengun Ihsan
Seo Koo Yong
Seok Lee Hyung
Seok Jinmyoung
Shabbir Yasmeen
Shabbir Yasmeen
Shah Akshay
Shah Amna
Shah Jaimin
Sharma Khema
Sheldon Danielle
Shimohama Shun
Shimohama Shun
Shimpo Misa
Shin Miju
Shiraishi Hirokazu
Siddiqi Zaeem
Sieren Jeri
Silva Marcela
Silvestri Nicholas
Smetcoren Charlotte
Smith Lisa
Snook Riley
Sohail Faisal
Sokratous Giannis
Souza Bulle Oliveira Acary
Souza Duca Luciana
Souza Iandra
Srinivasan Jayashri
Statland Jeffery
Steele Julie
Stevens Olivier
Strom Susan
Sub-Investigators
Sune Pilar
Suzuki Hidekazu
Suzuki Shuichiro
Suzuki Yasushi
Swenson Andrea
Szabadosne Brigitta
Szabo Gyorgyi
T So Yuen
Taichi Namie
Takada Kazumi
Takada Mihoko
Takahashi Masanori
Takeyama Rumi
Tandan Rup
Tano Ohito
Terzi Murat
Tilkin Petra
Tinerney Scott
Tobon Gonzalez Alejandro
Toncrova Stanislava
Torane Pravin
Toska Shirli
Tran Anh
Traub Rebecca
Trivedi Jaya
Troili Fernanda
Tsuda Emiko
Tsuda Tomoko
Tsukita Kenichi
Tsurumaru Masako
Tuga Celal
Tun Ozlem
Tyblova Michaela
Uehara Taira
Ugur Muzeyyen
Utsugisawa Kimiaki
Uwasa Kaori
Uzawa Akiyuki
Van Daele Sien
Van Damme Philip
Van den Abeele Guy
van der Kooi Anneke
Vandenbussche Nicolas
Vanderhook Mollie
Vanhee Annelies
Varga Edina
Varghese Mary
Vecsei Laszlo
Veiga Thabata
Velez Santamaria Valentina
Ventura Nicholas
Verjans Sarah
Veske Adife
Vidal Gonzalo
Vidal Nuria
Vinge Lotte
Vissing John
Vohanka Stanislav
Vu Hong
Vu Tuan
Vynckier Jan
Vytopil Michael
Wagemaekers Linda
Waheed Waqar
Walsh Maureen
Wang Yunxia
Watling Dave
Watt Elizabeth
Weiner Elaine
Weiss Michael
Welsh Lesly
Wheeler Lauren
Wilken Miguel
Witting Nanna
Wolfe Gil
Wolfova Marcela
Won Shin Chae
Woodall Amy
Yamamoto Daisuke
Yamashita Yumi
Yang Irene
Yasuda Ikuko
Ye Hwang Ji
Yilmaz Ezgi
Yoon Koh Da
Yoshida Seiko
Yoshida Seiko
Yoshimura Shunsuke
Youl Seok Hung
Young Shin Ha
Young Valerie
Zakalik Karen
Zapletalova Olga
Zilliox Lindsay
Publication venue: 'Springer Science and Business Media LLC'
Publication date: 01/01/2020
Field of study

The efficacy and tolerability of eculizumab were assessed in REGAIN, a 26-week, phase 3, randomized, double-blind, placebo-controlled study in anti-acetylcholine receptor antibody-positive (AChR+) refractory generalized myasthenia gravis (gMG), and its open-label extension

Archivio della ricerca- Università di Roma La Sapienza

Combining steady state and temperature jump IR spectroscopy to investigate the allosteric effects of ligand binding to dsDNA

Author: Clark IP
Dale J
Fritzsch R
Greetham GM
Howe CP
Hunt NT
McLeish TC
Parker AW
Toncrova H
Towrie M
Publication venue: 'Royal Society of Chemistry (RSC)'
Publication date: 01/01/2021
Field of study

ePubs: the open archive for STFC research publications

Global low-frequency motions in protein allostery: CAP as a model system

Author: A Bakan
A Brown
A Cooper
A Cornish-Bowden
A Zhuravleva
A Zhuravleva
AJ Wand
B Brooks
B Gorke
DE Koshland Jr
Ehmke Pohl
F Raimondi
F Tama
G Manley
H Toncrova
H Valadie
HN Motlagh
HN Motlagh
I Bahar
IA Balabin
J Monod
K Suhre
KA Reynolds
M Delarue
Mark R. Wilson
Martin J. Cann
MM Tirion
MT Zimmermann
N Go
N Popovych
P Durand
PD Townsend
Philip D. Townsend
RJ Hawkins
RJ Hawkins
RJ Hawkins
RJ Hawkins
S Maguid
S Maguid
S Nicolay
SR Tzeng
SR Tzeng
T Liu
TC McLeish
Thomas L. Rodgers
TL Rodgers
TL Rodgers
Tom C. B. McLeish
VJ Hilser
Publication venue: 'Springer Science and Business Media LLC'
Publication date: 04/02/2015
Field of study

Allostery is a fundamental process by which ligand binding to a protein alters its activity at a distant site. There is considerable evidence that allosteric cooperativity can be communicated by the modulation of protein dynamics without conformational change. The Catabolite Activator Protein (CAP) of Escherichia coli is an important experimental exemplar for entropically driven allostery. Here we discuss recent experimentally supported theoretical analysis that highlights the role of global low-frequency dynamics in allostery in CAP and identify how allostery arises as a natural consequence of changes in global low-frequency protein fluctuations on ligand binding

Crossref

Springer - Publisher Connector

PubMed Central

The University of Manchester - Institutional Repository

Terahertz optical measurements of correlated motions with possible allosteric function

Author: A. G. Markelz
AG Markelz
CJ Tsai
CL Brooks
DE Koshland
E Balog
E Balog
FG Parak
G Acbas
GS Edwards
H Toncrova
HN Motlagh
I Bahar
J Kröll
J Monod
JP Changeux
JW Powell
JW Powell
K Achterhold
K Gunasekaran
Katherine A. Niessen
KM Tych
LY Zhu
M Grossman
M Karplus
M Walther
MC Rheinstadter
Mengyang Xu
MM Teeter
P Petrone
R Biehl
R Chakkittakandy
R Nussinov
R Parthasarathy
R Singh
RE Bruccoleri
RJ Falconer
RM Levy
T Globus
T Weidlich
TCB McLeish
TM Korter
TQ Luong
TR Globus
TW Crowe
V Lisy
VJ Hilser
VJ Hilser
YF He
YM Xiao
Publication venue: 'Springer Science and Business Media LLC'
Publication date
Field of study

Crossref

Allosteric Activation via Kinetic Control: Potassium Accelerates a Conformational Change in IMP Dehydrogenase

Crossref

The Crystal Structures of Apo and cAMP-Bound GlxR from Corynebacterium glutamicum Reveal Structural and Dynamic Changes upon cAMP Binding in CRP/FNR Family Transcription Factors

Crossref

Long-term safety and efficacy of eculizumab in generalized myasthenia gravis

Author: Acar N. P.
Agrawal B.
Agriesti J.
Ahn S. -H.
Akhter S.
Akiyama T.
Alam S.
Alberti Aguilo M. A.
Alboini P. E.
Alcon K.
Alsharabati M.
Alves de Siqueira Carvalho A.
Amamoto S.
Amaral Andrade A. C.
Amato A.
Amato K.
Ambrosio D.
Ananias Morita M. D. P.
Andersen H.
Anderson A.
Andoin A.
Annes M.
Antonini G.
Antozzi C.
Aranke S.
Arndt H.
Arnold T.
Arribas-Ibar E.
Asada S.
Assis N.
Aydinlik S.
Balkan B.
Barohn R. J.
Barroso F.
Becerikli G.
Beck K.
Bednarik J.
Bekircan-Kurt C. E.
Benatar M.
Berger A. R.
Bertorini T.
Bettini M.
Beydoun S.
Bezerra Rosa B.
Bhavaraju-Sanka R.
Bilsker M.
Bjarbo L.
Blackmore D.
Bodkin C.
Bonanno S.
Bravver E.
Brooks B.
Brown C.
Burdette M.
Burns T. M.
Butinhao C. F.
Caliskan Y.
Callison K.
Camera G.
Campanella A.
Carnes D.
Carrara F.
Carter C.
Casasnovas C.
Cash T.
Cavalcante Lino V.
Cavus H.
Cesar P.
Chaudhry V.
Chaves M.
Chelnick S.
Chilingaryan A.
Chmelikova M.
Cho E. B.
Choi E. H.
Choi M.
Chopra M.
Cierny M.
Cochrane T.
Cooley A.
Corse A.
Cortes Vicente E.
Costabile T.
Cunningham S.
D'Amato V.
D'Hondt A.
da Cruz Pacheco D.
da Silva L. A.
Daniels K.
Darnell T.
Davies D.
de Bleecker J. L.
de Cassia Santos A.
de Koning K.
De Mey K.
de Visser M.
Depreitere A.
Dezsi L.
Di Pasquale A.
Dias Brockhausen I.
Diaz-Manera J.
Dicapua D.
Diez Porras L.
Diez Tejedor E.
Dimachkie M.
Dimitriou A.
Dimitrova D.
Disanzo B.
Dishman L.
Distad J.
Doan V.
Dogan B.
Donahue C.
Downing S.
Droker B.
Duarte Silva L.
Duran G.
Echevarria L.
Efendi H.
Elsayed M.
Emmons K.
Engel M.
Eralinna J. -P.
Erdem-Ozdamar S.
Eriksson J.
Evoli A.
Fasanaro A.
Feder D.
Fernandes P.
Fernandez-Fournier M.
Ferreira L.
Fialho T. A. S.
Filla A.
Fionda L.
Fionda L.
Fondaw A.
Forshew D.
Frasca V.
Frasca V.
Freimer M.
Fujii Y.
Fujita K. P.
Fukuda Y.
Funaka S.
Futono K.
Gabriele M.
Gamez J.
Garcia A. D.
Garcia R.
Garcia S.
Garibaldi M.
Gheller Friedrich M. A.
Giacomelli E.
Gibson T.
Gilchrist J.
Gili G.
Glenn M.
Golden L.
Gollogly J.
Gomes da Silva T. C.
Gomez Salcedo P.
Goncalves Geraldo J.
Gong H.
Gonzalez A.
Gori M.
Goyal N.
Goyal N.
Guerreiro A.
Guingrich S.
Guptill J.
Gutmann L.
Gutmann L.
Haar L.
Hafer-Macko C.
Harbo T.
Harrison T.
Hart A.
Harvey B.
Hasuike T.
Hayashi T.
Hehir M.
Hendersen K.
Herbelin L.
Herbert C.
Hewlett J.
Hietala A.
Higuchi E.
Hisahara S.
Ho D.
Hobson-Webb L.
Hojgaard J.
Homedes-Pedret C.
Hong Y. -H.
Hopkins S.
Horvath M.
Howard J. F.
Hoyle J. C.
Huynh K.
Hwang E. B.
Hwang J. Y.
Illa I.
Imai T.
Inghilleri M.
Iorio R.
Ishiyama N.
Ishiyama Y.
Jacob S.
Jakab G.
Jara J.
Jeffery D.
Jenci N.
Jeong H. -N.
Jerath N.
Jingu M.
Johns K.
Jones F.
Jones H. J.
Juel V.
Julia Palacios N.
Jung J.
Junkerova J.
Jurajdova I.
Kamakura S.
Kamegamori I.
Kanai T.
Kaneko Y.
Kang H. N.
Kanzaki A.
Karam C.
Karam C.
Karimi S.
Katz J.
Katzin L.
Kaur H.
Kawaguchi N.
Kawamata J.
Kawamura T.
Kazamel M.
Kelley A.
Keung B.
Khoury J.
Kikutake K.
Kim B.
Kim B. -J.
Kim B. J.
Kim M.
Kim S. M.
Kim Y. -H.
Kincaid J.
Kirbas Cavdar T.
Kissel J. T.
Kobashikawa T.
Kobayashi E.
Kobayashi H.
Koga M.
Koh D. Y.
Kohlrus S.
Konyane M.
Koo D. L.
Koo Y. S.
Kramer M.
Kressin N.
Krogh S.
Kumar A.
Kurihara R.
Kurkova B.
Kutlu A.
Kwan J.
Kwon J.
Laaksonen M.
Lazaro A.
Lee C. N.
Lee H.
Lee H. S.
Lee J.
Lim J. -S.
Lin F.
Liu T.
Liu Y.
Locatelli A.
Locheke J.
Lokaitis B.
Loor J.
Lopergolo D.
Lopez Ruiz P.
Lovas G.
Lu L.
Lucy S.
Macagnan A. P.
Maeda Y.
Maggi L.
Mahdi-Rogers M.
Mahieu D.
Maier G.
Makamori M.
Malekniazi A.
Mallon A.
Mantegazza R.
Maqsood F.
Marano E.
Marburger T.
Marsili A.
Martineli Torres D. D.
Martins Ribeiro R.
Masaki K.
Massey J.
Mathew V.
Matolcsi J.
Matsuse D.
Matsushita T.
Mazia C. G.
Mazuela G.
Mcclain T.
Mcclain T.
Mckenna K.
Mckinnon J.
Mckinnon N.
Mcvey A.
Meguro F.
Meherremova A.
Melo A. P.
Mercelis R.
Mezache L.
Micheels A.
Michon S. -C.
Miller R.
Min J. -H.
Minton B.
Miranda C.
Mitazaki T.
Miyawaki E.
Mizugami A.
Mogensen A.
Mohr H.
Mori M.
Morikawa M.
Morino S.
Mosmiller B.
Motomura M.
Mozaffar T.
Muharrem F.
Mukaino A.
Mumfrey-Thomas S.
Muppidi S.
Murahara T.
Murai H.
Nagane Y.
Nakamura Y.
Nance C.
Narayan J.
Narikawa K.
Nations S.
Naunton K.
Nemeth J.
Nogueira Coelho E.
Norwood F.
Noshiro M.
Novakova I.
Nowak R. J.
Nozaki K.
Nye J.
O'Brien F. L.
Oksaranta O.
Okumura M.
Olalde H.
Onar M. K.
Onesti E.
Orsel G.
Osakada K.
Ostergaard Autzen A.
Otavio Maia Goncalves L.
Ozawa Y.
Ozcelik P.
Padilla P.
Paiva G.
Park S.
Pasanisi M.
Pascuzzi R.
Pasnoor M.
Patrick K.
Patwa H.
Paulose S.
Pazetto L. E.
Pedersen J.
Pereira Martins M.
Phan C.
Piehl F.
Pillai R.
Pineda C.
Pinto G.
Pinto W.
Pitha J.
Plevka S.
Pokala K.
Pol S.
Pozo M.
Prando N.
Pulley M.
Puorro G.
Querol Gutierrez L. A.
Ra H.
Reguliova K.
Renata Cubas Volpe L.
Reyes E.
Rico G.
Robeson K.
Rocha R.
Roderus R.
Rodriguez de Rivera F. J.
Roe K.
Rojas Garcia R.
Rosenfeld J.
Roy G.
Rozsa C.
Rugiero M.
Saba J.
Sacca F.
Sadalage G.
Saito Y.
Saitoh M.
Sakamuri S.
Saklad A.
Salajegheh M.
Salvado M.
Samukawa M.
Sanjak M.
Sano Y.
Santos Engel M.
Sastre M.
Sathasivam S.
Sato M.
Sattar N.
Scala S.
Schommer C.
Schotte C.
Seddigh A.
Seelback J.
Semiz C.
Sen S.
Sengun I.
Seok H. Y.
Seok J.
Shabbir Y.
Shah A.
Shah A.
Shah J.
Sharma K.
Sheldon D.
Shimohama S.
Shimpo M.
Shin C. W.
Shin H. Y.
Shin M.
Shiraishi H.
Siddiqi Z.
Sieren J.
Silva M.
Silvestri N.
Smetcoren C.
Smith L.
Snook R.
So Y. T.
Sohail F.
Sokratous G.
Souza Bulle Oliveira A.
Souza Duca L.
Souza I.
Srinivasan J.
Statland J.
Steele J.
Stevens O.
Strom S.
Sune P.
Suzuki H.
Suzuki S.
Suzuki Y.
Swenson A.
Szabadosne B.
Szabo G.
Taichi N.
Takada K.
Takada M.
Takahashi M.
Takeyama R.
Tandan R.
Tano O.
Terzi M.
Tierney S.
Tilkin P.
Tobon Gonzales A.
Toncrova S.
Torane P.
Toska S.
Tran A.
Traub R.
Trivedi J.
Troili F.
Tsuda E.
Tsuda T.
Tsukita K.
Tsurumaru M.
Tuga C.
Tun O.
Tyblova M.
Uehara T.
Ugur M.
Utsugisawa K.
Uwasa K.
Uzawa A.
Van Daele S.
Van Damme P.
Van den Abeele G.
van der Kooi A.
Vandenbussche N.
Vanderhook M.
Vanhee A.
Varga E.
Varghese M.
Vecsei L.
Veiga T.
Velez Santamaria V.
Ventura N.
Verjans S.
Veske A.
Vidal G.
Vidal N.
Vinge L.
Vissing J.
Vohanka S.
Vu H.
Vu T. H.
Vynckier J.
Vytopil M.
Wagemaekers L.
Waheed W.
Walsh M.
Wang J. J.
Wang Y.
Watling D.
Watt E.
Weiner E.
Weiss M.
Welsh L.
Wheeler L.
Wilken M.
Witting N.
Wolfe G.
Wolfova M.
Woodall A.
Yamamoto D.
Yamashita Y.
Yang I.
Yasuda I.
Yilmaz E.
Yoshida S.
Yoshimura S.
Young V.
Zakalik K.
Zapletalova O.
Zilliox L.
Publication venue: 'Wiley'
Publication date: 01/01/2019
Field of study

Introduction: Eculizumab is effective and well tolerated in patients with antiacetylcholine receptor antibody-positive refractory generalized myasthenia gravis (gMG; REGAIN; NCT01997229). We report an interim analysis of an open-label extension of REGAIN, evaluating eculizumab's long-term safety and efficacy. Methods: Eculizumab (1,200 mg every 2 weeks for 22.7 months [median]) was administered to 117 patients. Results: The safety profile of eculizumab was consistent with REGAIN; no cases of meningococcal infection were reported during the interim analysis period. Myasthenia gravis exacerbation rate was reduced by 75% from the year before REGAIN (P < 0.0001). Improvements with eculizumab in activities of daily living, muscle strength, functional ability, and quality of life in REGAIN were maintained through 3 years; 56% of patients achieved minimal manifestations or pharmacological remission. Patients who had received placebo during REGAIN experienced rapid and sustained improvements during open-label eculizumab (P < 0.0001). Discussion: These findings provide evidence for the long-term safety and sustained efficacy of eculizumab for refractory gMG. Muscle Nerve 2019

Archivio della ricerca - Università degli studi di Napoli Federico II

Archivio della ricerca- Università di Roma La Sapienza