The impacts of climate change on Greek airports

Time series of meteorological parameters at ten Greek airports since 1955 indicated the level of climate change in the Eastern Mediterranean area. Using this data, take-off performance was analysed for the DHC-8-400—a typical short range turboprop airliner, and the A320, a typical medium scale turbofan airliner. For airports with longer runways, a steady but unimportant increase in take-off distances was found. For airports with shorter runways, the results indicate a steady reduction in available payload. At the most extreme case, results show that for an Airbus A320, operating from the, relatively short, 1511m runway at Chios Airport, the required reduction in payload would be equivalent to 38 passengers with their luggage, or fuel for 700 nautical miles (1300 km) per flight, for the period between the A320’s entry to service in 1988 and 2017. These results indicate that for airports where aeroplane maximum take-off mass is a performance limited function of runway length, and where minimum temperatures have increased and/or mean headwind components decreased, climate change has already had a marked impact on the economic activity in the airline industry. Similar analyses could be usefully carried out for other runway-length–limited airports, which may often include island airports. It is also noted that previous research has only considered temperature effects, and not wind effects. Wind effects in this study are less significant than temperature, but nonetheless have an effect on both field performance noise and pollution nuisance around airports

南極沿岸ポリニヤにおける海氷生産量の年変動

第6回極域科学シンポジウム分野横断セッション：[IG] 全球環境変動を駆動する南大洋・南極氷床11月17日（火）　国立極地研究所 2階 大会議

Perceptual grouping based on iterative multi-scale tensor voting

Abstract. We propose a new approach for perceptual grouping of oriented segments in highly cluttered images based on tensor voting. Segments are represented as second-order tensors and communicate with each other through a voting scheme that incorporates the Gestalt principles of visual perception. An iterative scheme has been devised which removes noise segments in a conservative way using multi-scale analysis and re-voting. We have tested our approach on data sets composed of real objects in real backgrounds. Our experimental results indicate that our method can segment successfully objects in images with up to twenty times more noise segments than object ones.

Experimental determination of zinc isotope fractionation in complexes with the phytosiderophore 2′-deoxymugeneic acid (DMA) and its structural analogues, and implications for plant uptake mechanisms

The stable isotope signatures of zinc and other metals are increasingly used to study plant and soil processes. Complexation with phytosiderophores is a key reaction and understanding the controls of isotope fractionation is central to such studies. Here, we investigated isotope fractionation during complexation of Zn2+ with the phytosiderophore 2′-deoxymugeneic acid (DMA), and with three commercially available structural analogues of DMA: EDTA, TmDTA, and CyDTA. We used ion exchange chromatography to separate free and complexed zinc, and identified appropriate cation exchange resins for the individual systems. These were Chelex-100 for EDTA and CyDTA, Amberlite CG50 for TmDTA and Amberlite IR120 for DMA. With all the ligands we found preferential partitioning of isotopically heavy zinc in the complexed form, and the extent of fractionation was independent of the Zn:ligand ratio used, indicating isotopic equilibrium and that the results were not significantly affected by artifacts during separation. The fractionations (in ‰) were +0.33 ± 0.07 (1σ, n = 3), + 0.45 ± 0.02 (1σ, n = 2), + 0.62 ± 0.05 (1σ, n = 3) and +0.30 ± 0.07 (1σ, n = 4) for EDTA, TmDTA, CyDTA, and DMA, respectively. Despite the similarity in Zn-coordinating donor groups, the fractionation factors are significantly different and extent of fractionation seems proportional to the complexation stability constant. The extent of fractionation with DMA agreed with observed fractionations in zinc uptake by paddy rice in field experiments, supporting the possible involvement of DMA in zinc uptake by rice

Distinctive Personality Traits and Neural Correlates Associated with Stimulant Drug Use Versus Familial Risk of Stimulant Dependence

BackgroundStimulant drugs such as cocaine and amphetamine have a high abuse liability, but not everyone who uses them develops dependence. However, the risk for dependence is increased for individuals with a family history of addiction. We hypothesized that individuals without a family history of dependence who have been using cocaine recreationally for several years but have not made the transition to dependence will differ in terms of personality traits and brain structure from individuals who are either dependent on stimulants or at risk for dependence.MethodsWe compared 27 individuals without a familial risk of dependence who had been using cocaine recreationally with 50 adults with stimulant dependence, their nondependent siblings (n = 50), and unrelated healthy volunteers (n = 52) who had neither a personal nor a family history of dependence. All participants underwent a magnetic resonance imaging brain scan and completed a selection of personality measures that have been associated with substance abuse.ResultsIncreased sensation-seeking traits and abnormal orbitofrontal and parahippocampal volume were shared by individuals who were dependent on stimulant drugs or used cocaine recreationally. By contrast, increased levels of impulsive and compulsive personality traits and limbic-striatal enlargement were shared by stimulant-dependent individuals and their unaffected siblings.ConclusionsWe provide evidence for distinct neurobiological phenotypes that are either associated with familial vulnerability for dependence or with regular stimulant drug use. Our findings further suggest that some individuals with high sensation-seeking traits but no familial vulnerability for dependence are likely to use cocaine but may have relatively low risk for developing dependence

Brain networks underlying vulnerability and resilience to drug addiction.

Regular drug use can lead to addiction, but not everyone who takes drugs makes this transition. How exactly drugs of abuse interact with individual vulnerability is not fully understood, nor is it clear how individuals defy the risks associated with drugs or addiction vulnerability. We used resting-state functional MRI (fMRI) in 162 participants to characterize risk- and resilience-related changes in corticostriatal functional circuits in individuals exposed to stimulant drugs both with and without clinically diagnosed drug addiction, siblings of addicted individuals, and control volunteers. The likelihood of developing addiction, whether due to familial vulnerability or drug use, was associated with significant hypoconnectivity in orbitofrontal and ventromedial prefrontal cortical-striatal circuits-pathways critically implicated in goal-directed decision-making. By contrast, resilience against a diagnosis of substance use disorder was associated with hyperconnectivity in two networks involving 1) the lateral prefrontal cortex and medial caudate nucleus and 2) the supplementary motor area, superior medial frontal cortex, and putamen-brain circuits respectively implicated in top-down inhibitory control and the regulation of habits. These findings point toward a predisposing vulnerability in the causation of addiction, related to impaired goal-directed actions, as well as countervailing resilience systems implicated in behavioral regulation, and may inform novel strategies for therapeutic and preventative interventions.This research was funded by a Medical Research Council (MRC) grant (G0701497), financially supported by the NIHR Cambridge Biomedical Research Centre, and conducted within the Behavioural and Clinical Neuroscience Institute (BCNI). CM was supported by the Wellcome Trust grant to KDE (105602/Z/14/Z) and the NIHR Cambridge Biomedical Research Centre. JS was partly supported by the NIHR CLAHRC East of England and by the Charles University PRVOUK programme P38. TWR is a recipient of a Wellcome Trust Senior Investigator Award (104631/z/14/z). TWR discloses consultancy with Cambridge Cognition, Greenfield Bioventures and Unilever; he receives royalties for CANTAB from Cambridge Cognition, research grants from Shionogi and GlaxoSmithKline and editorial honoraria from Springer Verlag and Elsevier. ETB is a National Institute for Health Research Senior Investigator

National First Peoples Gathering on Climate Change

Our purpose in hosting the National First Peoples Gathering on Climate Change (the Gathering) was to celebrate, learn from and enhance First Peoples-led climate action. We set out to strengthen kinships, cultural identity and well-being, and to strengthen caring for Country by using both Indigenous and scientific knowledge. The Gathering supported this overall purpose through five aims:• Bring Traditional Owners together to share with one another about climate change • Share scientific information in a form useful for Traditional Owners• Identify options for policy to respond to climate change • Provide tangible information to take back to communities• Highlight First Peoples’ climate change actions. 110 Traditional Owners from across Australia attended the Gathering

A new liver perfusion and preservation system for transplantation Research in large animals

A kidney perfusion machine, model MOX-100 (Waters Instruments, Ltd, Rochester, MN) was modified to allow continuous perfusion of the portal vein and pulsatile perfusion of the hepatic artery of the liver. Additional apparatus consists of a cooling system, a membrane oxygenator, a filter for foreign bodies, and bubble traps. This system not only allows hypothermic perfusion preservation of the liver graft, but furthermore enables investigation of ex vivo simulation of various circulatory circumstances in which physiological perfusion of the liver is studied. We have used this system to evaluate the viability of liver allografts preserved by cold storage. The liver was placed on the perfusion system and perfused with blood with a hematocrit of approximately 20% and maintained at 37°C for 3 h. The flows of the hepatic artery and portal vein were adjusted to 0.33 mL and 0.67 mL/g of liver tissue, respectively. Parameters of viability consisted of hourly bile output, oxygen consumption, liver enzymes, electrolytes, vascular resistance, and liver histology. This method of liver assessment in large animals will allow the objective evaluation of organ viability for transplantation and thereby improve the outcome of organ transplantation. Furthermore, this pump enables investigation into the pathophysiology of liver ischemia and preservation. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted