40 research outputs found
A Multi-Agent Evolutionary algorIthm for Connector-Based Assembly Sequence Planning
AbstractSome Evolutionary algorithms for connector-based ASP have been researched. But those algorithms have lots of blind searching because individuals have little intelligence in making use of geometry and assembly process information of product assembly body. To improve individuals’ intelligence, A multi-agent evolutionary algorithm for connector-based ASP (MAEA-ASP) is presented which is integrated with the multi-agent systems. learning, competition and crossover -mutation are designed as the behaviors of agent which locate lattice-like structure environment. Experimental results show that MAEA-ASP can find an approximate solution faster compared with other evolutionary algorithms
The Technology of Mould Steel for Online Pre-hardening
AbstractThis article describes a production method of mould steel pre-hardening, and focus on the advantage of this method, The technical core of method is the variable frequency and variable amplitude pulse uniform high-precision temperature control, which achieved by using strong-medium-weak water cooling, gas-water cooling and gas mist cooling composite cooling control technology. Optimizing the cooling rate path is a good method of optimizing quenched organization and structure
Oxygen-Glucose-Deprivation/Reoxygenation-Induced Autophagic Cell Death Depends on JNK-Mediated Phosphorylation of Bcl-2
Evaluation of surgical outcome of Jack vertebral dilator kyphoplasty for osteoporotic vertebral compression fracture—clinical experience of 218 cases
Methylprednisolone as Adjunct to Endovascular Thrombectomy for Large-Vessel Occlusion Stroke
Importance
It is uncertain whether intravenous methylprednisolone improves outcomes for patients with acute ischemic stroke due to large-vessel occlusion (LVO) undergoing endovascular thrombectomy.
Objective
To assess the efficacy and adverse events of adjunctive intravenous low-dose methylprednisolone to endovascular thrombectomy for acute ischemic stroke secondary to LVO.
Design, Setting, and Participants
This investigator-initiated, randomized, double-blind, placebo-controlled trial was implemented at 82 hospitals in China, enrolling 1680 patients with stroke and proximal intracranial LVO presenting within 24 hours of time last known to be well. Recruitment took place between February 9, 2022, and June 30, 2023, with a final follow-up on September 30, 2023.InterventionsEligible patients were randomly assigned to intravenous methylprednisolone (n = 839) at 2 mg/kg/d or placebo (n = 841) for 3 days adjunctive to endovascular thrombectomy.
Main Outcomes and Measures
The primary efficacy outcome was disability level at 90 days as measured by the overall distribution of the modified Rankin Scale scores (range, 0 [no symptoms] to 6 [death]). The primary safety outcomes included mortality at 90 days and the incidence of symptomatic intracranial hemorrhage within 48 hours.
Results
Among 1680 patients randomized (median age, 69 years; 727 female [43.3%]), 1673 (99.6%) completed the trial. The median 90-day modified Rankin Scale score was 3 (IQR, 1-5) in the methylprednisolone group vs 3 (IQR, 1-6) in the placebo group (adjusted generalized odds ratio for a lower level of disability, 1.10 [95% CI, 0.96-1.25]; P = .17). In the methylprednisolone group, there was a lower mortality rate (23.2% vs 28.5%; adjusted risk ratio, 0.84 [95% CI, 0.71-0.98]; P = .03) and a lower rate of symptomatic intracranial hemorrhage (8.6% vs 11.7%; adjusted risk ratio, 0.74 [95% CI, 0.55-0.99]; P = .04) compared with placebo.
Conclusions and Relevance
Among patients with acute ischemic stroke due to LVO undergoing endovascular thrombectomy, adjunctive methylprednisolone added to endovascular thrombectomy did not significantly improve the degree of overall disability.Trial RegistrationChiCTR.org.cn Identifier: ChiCTR210005172
Online Social Network Evolving Model Based on Damping Factor
AbstractRecently the evolving model of network has become one of hot research topics. Since the BA model is presented, many kinds of evolving models have been proposed. However the generation mechanism of existing evolving model of online social network has certain limitation, i.e. researchers mostly focus on the factors that facilitating network growth but ignore the factors that delaying network growth. In order to resolve this limitation, a new online social network evolving model (DFEM) is proposed in this paper. In this model, the factors delaying network growth are defined as damping factor and which is divided into the decline of initial attraction, the loss of node heat, and irresistible natural factors. In addition, the damping factors, the attractive factors, and the degree of nodes are taken into consideration together in the preference link. The results of theoretical analysis and numerical simulation suggest that the degree distribution of network generated by DFEM model is more correspond with existing online social network
Timed petri-net based formulation and an algorithm for the optimal scheduling of batch plants
The effective scheduling of operations in batch plants has a great potential for high economic returns, in which the formulation and an optimal solution algorithm are the main issues of study. Petri nets have proven to be a promising technique for solving many difficult problems associated with the modelling, formal analysis, design and coordination control of discrete-event systems. One of the major advantages of using a Petri-net model is that the same model can be used for the analysis of behavioural properties and performance evaluation, as well as for the systematic construction of discrete-event simulators and controllers. This paper aims at presenting a Petri-net based approach to the scheduling of operations in batch plants. Firstly, the short term of the ‘scheduling of batch plants ’ is formulated by means of a timed Petri net which can accommodate various intermediate storage policies, such as unlimited intermediate storage (UIS), no intermediate storage (NIS), finite intermediate storage (FIS), and mixed intermediate storage (MIS). Secondly, a heuristic search algorithm for the optimal scheduling of batch plants is given, which is based on generating and checking the markings in the reachability tree of the Petri-net model. Finally, the novel formulation and algorithm are tested with several simulation case studies
A Topology Evolution Model Based on Revised PageRank Algorithm and Node Importance for Wireless Sensor Networks
Wireless sensor network (WSN) is a classical self-organizing communication network, and its topology evolution currently becomes one of the attractive issues in this research field. Accordingly, the problem is divided into two subproblems: one is to design a new preferential attachment method and the other is to analyze the dynamics of the network topology evolution. To solve the first subproblem, a revised PageRank algorithm, called Con-rank, is proposed to evaluate the node importance upon the existing node contraction, and then a novel preferential attachment is designed based on the node importance calculated by the proposed Conrank algorithm. To solve the second one, we firstly analyze the network topology evolution dynamics in a theoretical way and then simulate the evolution process. Theoretical analysis proves that the network topology evolution of our model agrees with power-law distribution, and simulation results are well consistent with our conclusions obtained from the theoretical analysis and simultaneously show that our topology evolution model is superior to the classic BA model in the average path length and the clustering coefficient, and the network topology is more robust and can tolerate the random attacks
Symbolic ZBDD Representations for Mechanical Assembly Sequences
Part 7: Knowledge RepresentationInternational audienceThe representations of assembly knowledge and assembly sequences are crucial in assembly planning, where the size of parts involved is a significant and often prohibitive difficulty. Zero-suppressed binary decision diagram (ZBDD) is an efficient form to represent and manipulate the sets of combination, and appears to give improved results for large-scale combinatorial optimization problems. In this paper, liaison graphs, translation functions, assembly states and assembly tasks are represented as sets of combinations, and the symbolic ZBDD representation of assembly sequences is proposed. An example is given to show the feasibility of the ZBDD-based representation scheme