Observing Galaxy Clusters with eROSITA: Simulations

The eROSITA instrument on board the Russian Spectrum Roentgen Gamma spacecraft, which will be launched in 2013,will conduct an all sky survey in X-rays. A main objective of the survey is to observe galaxy clusters in order to constrain cosmological parameters and to obtain further knowledge about dark matter and dark energy. For the simulation of the eROSITA survey we present a Monte-Carlo code generating a mock catalogue of galaxy clusters distributed accordingto the mass function of [1]. The simulation generates the celestial coordinates as well as the cluster mass and redshift. From these parameters, the observed intensity and angular diameter are derived. These are used to scale Chandra cluster images as input for the survey-simulation

Mechanisms of StpA-mediated RNA remodeling

In bacteria, transcription, translation and gene regulation are highly coupled processes. The achievement of a certain functional structure at a distinct temporal and spatial position is therefore essential for RNA molecules. Proteins that facilitate this proper folding of RNA molecules are called RNA chaperones. Here a prominent example from E. coli is reviewed: the nucleoid associated protein StpA. Based on its various RNA remodeling functions, we propose a mechanistic model that explains how StpA promotes RNA folding. Through transient interactions via the RNA backbone, thereby shielding repelling charges in RNA, it pre-positions the RNA molecules for the successful formation of transition states from encounter complexes