640 research outputs found
Optical calibration hardware for the Sudbury Neutrino Observatory
The optical properties of the Sudbury Neutrino Observatory (SNO) heavy water
Cherenkov neutrino detector are measured in situ using a light diffusing sphere
("laserball"). This diffuser is connected to a pulsed nitrogen/dye laser via
specially developed underwater optical fibre umbilical cables. The umbilical
cables are designed to have a small bending radius, and can be easily adapted
for a variety of calibration sources in SNO. The laserball is remotely
manipulated to many positions in the D2O and H2O volumes, where data at six
different wavelengths are acquired. These data are analysed to determine the
absorption and scattering of light in the heavy water and light water, and the
angular dependence of the response of the detector's photomultiplier tubes.
This paper gives details of the physical properties, construction, and optical
characteristics of the laserball and its associated hardware.Comment: 17 pages, 8 figures, submitted to Nucl. Inst. Meth.
Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1
We report several receptor tyrosine kinase (RTK) ligands increase RhoA-guanosine triphosphate (GTP) in untransformed and transformed cell lines and determine this phenomenon depends on the RTKs activating the AKT serine/threonine kinase. The increased RhoA-GTP results from AKT phosphorylating three serines (S298, S329, and S567) in the DLC1 tumor suppressor, a Rho GTPase-activating protein (RhoGAP) associated with focal adhesions. Phosphorylation of the serines, located N-terminal to the DLC1 RhoGAP domain, induces strong binding of that N-terminal region to the RhoGAP domain, converting DLC1 from an open, active dimer to a closed, inactive monomer. That binding, which interferes with the interaction of RhoA-GTP with the RhoGAP domain, reduces the hydrolysis of RhoA-GTP, the binding of other DLC1 ligands, and the colocalization of DLC1 with focal adhesions and attenuates tumor suppressor activity. DLC1 is a critical AKT target in DLC1-positive cancer because AKT inhibition has potent antitumor activity in the DLC1-positive transgenic cancer model and in a DLC1-positive cancer cell line but not in an isogenic DLC1-negative cell line
Electromagnetic Interactions GEneRalized (EIGER) - Algorithm abstraction and HPC implementation
Modern software development methods combined with key generalizations of standard computational algorithms enable the development of a new class of electromagnetic modeling tools. This paper describes current and anticipated capabilities of a frequency domain modeling code, EIGER, which has an extremely wide range of applicability. In addition, software implementation methods and high performance computing issues are discussed
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Physical Separation of Straw Stem Components to Reduce Silica
In this paper, we describe ongoing efforts to solve challenges to using straw for bioenergy and bioproducts. Among these, silica in straw forms a low-melting eutectic with potassium, causing slag deposits, and chlorides cause corrosion beneath the deposits. Straw consists principally of stems, leaves, sheaths, nodes, awns, and chaff. Leaves and sheaths are higher in silica, while chaff, leaves and nodes are the primary source of fines. Our approach to reducing silica is to selectively harvest the straw stems using an in-field physical separation, leaving the remaining components in the field to build soil organic matter and contribute soil nutrients
Dynamic scaling and quasi-ordered states in the two dimensional Swift-Hohenberg equation
The process of pattern formation in the two dimensional Swift-Hohenberg
equation is examined through numerical and analytic methods. Dynamic scaling
relationships are developed for the collective ordering of convective rolls in
the limit of infinite aspect ratio. The stationary solutions are shown to be
strongly influenced by the strength of noise. Stationary states for small and
large noise strengths appear to be quasi-ordered and disordered respectively.
The dynamics of ordering from an initially inhomogeneous state is very slow in
the former case and fast in the latter. Both numerical and analytic
calculations indicate that the slow dynamics can be characterized by a simple
scaling relationship, with a characteristic dynamic exponent of in the
intermediate time regime
Inverse flux quantum periodicity of magnetoresistance oscillations in two-dimensional short-period surface superlattices
Transport properties of the two-dimensional electron gas (2DEG) are
considered in the presence of a perpendicular magnetic field and of a {\it
weak} two-dimensional (2D) periodic potential modulation in the 2DEG plane. The
symmetry of the latter is rectangular or hexagonal. The well-known solution of
the corresponding tight-binding equation shows that each Landau level splits
into several subbands when a rational number of flux quanta pierces the
unit cell and that the corresponding gaps are exponentially small. Assuming the
latter are closed due to disorder gives analytical wave functions and
simplifies considerably the evaluation of the magnetoresistivity tensor
. The relative phase of the oscillations in and
depends on the modulation periods involved. For a 2D modulation
with a {\bf short} period nm, in addition to the Weiss oscillations
the collisional contribution to the conductivity and consequently the tensor
show {\it prominent peaks when one flux quantum passes
through an integral number of unit cells} in good agreement with recent
experiments. For periods nm long used in early experiments, these
peaks occur at fields 10-25 times smaller than those of the Weiss oscillations
and are not resolved
Toric AdS4/CFT3 duals and M-theory Crystals
We study the recently proposed crystal model for three dimensional
superconformal field theories arising from M2-branes probing toric Calabi-Yau
four-fold singularities. We explain the algorithms mapping a toric Calabi-Yau
to a crystal and vice versa, and show how the spectrum of BPS meson states fits
into the crystal model.Comment: 24 pages, 24 figure
Counting Chiral Operators in Quiver Gauge Theories
We discuss in detail the problem of counting BPS gauge invariant operators in
the chiral ring of quiver gauge theories living on D-branes probing generic
toric CY singularities. The computation of generating functions that include
counting of baryonic operators is based on a relation between the baryonic
charges in field theory and the Kaehler moduli of the CY singularities. A study
of the interplay between gauge theory and geometry shows that given geometrical
sectors appear more than once in the field theory, leading to a notion of
"multiplicities". We explain in detail how to decompose the generating function
for one D-brane into different sectors and how to compute their relevant
multiplicities by introducing geometric and anomalous baryonic charges. The
Plethystic Exponential remains a major tool for passing from one D-brane to
arbitrary number of D-branes. Explicit formulae are given for few examples,
including C^3/Z_3, F_0, and dP_1.Comment: 75 pages, 22 figure
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