3 research outputs found

    The distribution of mistyping probabilities for the markers in chromosome 7 is shown on the left, and the proportion of genotypes blanked on the right, as determined by the mistyping probability thresholds on the x-axis

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    <p><b>Copyright information:</b></p><p>Taken from "Pedigree and genotype errors in the Framingham Heart Study"</p><p>http://www.biomedcentral.com/1471-2156/4/s1/S41</p><p>BMC Genetics 2003;4(Suppl 1):S41-S41.</p><p>Published online 31 Dec 2003</p><p>PMCID:PMC1866477.</p><p></p> We chose to blank genotypes with mistyping probabilities greater or equal to 0.25

    Scatter diagrams of the IBD probabilities estimated by PREST on a relationship triangle reveal the extent of pedigree errors within a given relationship category

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    <p><b>Copyright information:</b></p><p>Taken from "Pedigree and genotype errors in the Framingham Heart Study"</p><p>http://www.biomedcentral.com/1471-2156/4/s1/S41</p><p>BMC Genetics 2003;4(Suppl 1):S41-S41.</p><p>Published online 31 Dec 2003</p><p>PMCID:PMC1866477.</p><p></p> By far, the largest number of errors involves "unrelated" pairs that in fact appear to be related

    In the Framingham data the four offspring in the third generation were assigned mother C, but the tests identified A as the biological mother

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    <p><b>Copyright information:</b></p><p>Taken from "Pedigree and genotype errors in the Framingham Heart Study"</p><p>http://www.biomedcentral.com/1471-2156/4/s1/S41</p><p>BMC Genetics 2003;4(Suppl 1):S41-S41.</p><p>Published online 31 Dec 2003</p><p>PMCID:PMC1866477.</p><p></p> B was confirmed as the biological father. The dashed lines indicate the corrected relationships
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