La situación en la Argentina : asma bronquial

Fil: Gené, Ricardo J. Universidad de Buenos Aires. Hospital de Clínicas; Argentina.El asma bronquial es un serio problema de salud. Una enfermedad frecuente "alrededor de 300\nmillones de personas" que puede ser lo suficientemente intensa como para afectar seriamente la\ncalidad de vida de los que la padecen y que impide su normal desarrollo de sus actividades. En este\nartículo, se evalúan datos epidemiológicos sobre el asma bronquial en la Argentina y en el mundo, así\ncomo también cuál es el grado de control que se tiene sobre esta enfermedad. Se comentan, además,\nlos resultados de estudios obtenidos en el Hospital de Clínicas con un elevado número de pacientes\nque concurrieron a ser evaluados en la primera semana de mayo del 2004, cuando se conmemora el\nDía Mundial del Asma Bronquial (primer martes de mayo), como parte de un estudio "denominado\nISAAC" que se realizó siguiendo una misma metodología en 54 países, y que muestra que la\nArgentina tiene una prevalencia intermedia en el concierto de las naciones que intervinieron

A universal specification for multicore fiber crosstalk

© 2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes,creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.In order to transition multi-core fiber (MCF) technologies from their research state to volume production, the key design specifications have to be broadly agreed upon, first and foremost an acceptable level of inter-core crosstalk per unit length. Against common belief, we show that MCF crosstalk requirements per unit length are fairly independent of transmission distance in the context of modern coherent optical communication systems. As a consequence, a single value for the tolerable inter-core crosstalk per unit length can be used to specify MCFs, valid from metropolitan (~100 km) to trans-pacific (~10 000 km) deployment scenarios. The notion of a universal inter-core crosstalk specification allows for application-independent MCF designs (including a distance-independent optimum core density) and will facilitate the standardization and volume manufacturing of MCF.Peer ReviewedPostprint (author's final draft

Daylight photodynamic therapy using methylene blue to treat sheep with dermatophytosis caused by Arthroderma vanbreuseghemii

Arthroderma vanbreuseghemii has been identified molecularly as the causative agent of dermatophytosis in a flock of sheep. It is necessary to explore new treatment alternatives because antifungals are not approved for use on small ruminant animals in the European Union. Antimicrobial photodynamic therapy (aPDT) has been shown to be effective for the treatment of dermatophytosis in humans. It is based on the application of a photosensitizer such as methylene blue (MB) that is activated by visible light to generate reactive oxygen species that are cytotoxic to cells. The use of daylight to perform aPDT (aDL-PDT) avoids the requirement of specific equipment because it uses sunlight to activate the photosensitizer. The aim of our study is to determine the efficacy of aDL-PDT using a 1% MB solution to treat dermatophytosis caused by A. vanbreuseghemii in ewes. Two different topical protocols (1% MB solution spray applications once or twice a week) were assayed in two groups of five infected animals. Twenty-five infected sheep were untreated. All the sheep were exposed to sunlight every day for an approximate duration of 10 h for a total of four weeks. At the end of the study, all the animals treated with aDL-PDT showed the same clinical response to both protocols. In contrast, the animals exposed only to sunlight required an additional two to four weeks before their infections resolved. Conclusion: aDL-PDT with 1% MB solution demonstrates efficacy, safety and efficiency in the treatment of dermatophytosis in sheep

Gingival and submandibular lymph node metastasis of sigmoid colon adenocarcinoma

Introduction: Metastatic tumors of oral and maxillofacial region compromise 1% of all malignant oral neoplasms. Most commonly affect the jaw bone and less commonly intraoral soft tissues. They originate mainly from primary tumors of lung, breast, colon-rectum, prostate and kidney. Case report: a 77 years old man with history of sigmoid colon adenocarcinoma and liver metastasis. Two years later of being free of disease, he presented with submandi- bular lymphadenopathy and a gingival mass in right upper jaw. Fine needle aspiration of the node and biopsy of the gingival mass were performed. The cytological smears showed cohesive cell groups on a necrotic background. Biopsy examination showed subepithelial infiltration by neoplasm of glandular pattern with immunoreactivity for keratin 20 and carcinoembryonic antigen. A definitive diagnosis of node and oral metastases of colon adenocarcinoma was made. Discussion: Metastases in the oral and maxillofacial region are very uncommon and usually represent an advanced stage and disseminated disease. They present non specific radiologic and clinical features so it is imperative to reach a definitive diagnosis the cytological/histological examination. Because of its rarity, the diagnosis of metastases in the oral region are a challenging, both to the clinician and to the pathologist, in recogni- sing that a lesion is metastasic and in determining the site of origi

Extending MOOC ecosystems using web services and software architectures

[EN]This paper present a research project that tries to extend the MOOC ecosystems by integrating external tools like social networks. This integration is developed by using a software architecture that mediate between the different systems and platforms establishing communication workflows and analyzing the information retrieved. This kind of system is applied in a real case, and it allows teachers and managers of the MOOC platform to get enhanced information and insights about users interaction with contents and MOOC tools, as well as some metrics impossible to retrieve or calculate manually in this kind of eLearning platforms with high amounts of users