73 research outputs found
Evolving dimensions in medical case reporting
Medical case reports (MCRs) have been undervalued in the literature to date. It seems that while case series emphasize what is probable, case reports describe what is possible and what can go wrong. MCRs transfer medical knowledge and act as educational tools. We outline evolving aspects of the MCR in current practice
Prognostic limitations of the Eurotransplant-donor risk index in liver transplantation
Industry-sponsored clinical research outside high-income countries: an empirical analysis of registered clinical trials from 2006 to 2013
Deep interpretable mortality model for intensive care unit risk prediction
Estimating the mortality of patients plays a fundamental role in an intensive care unit (ICU). Currently, most learning approaches are based on deep learning models. However, these approaches in mortality prediction suffer from two problems: (i) the specificity of causes of death are not considered in the learning process due to the different diseases, and symptoms are mixed-used without diversification and localization; (ii) the learning outcome for the mortality prediction is not self-explainable for the clinicians. In this paper, we propose a Deep Interpretable Mortality Model (DIMM), which employs Multi-Source Embedding, Gated Recurrent Units (GRU), Attention mechanism and Focal Loss techniques to prognosticate mortality prediction. We intensified the mortality prediction by considering the different clinical measures, medical treatments and the heterogeneity of the disease. More importantly, for the first time, in this framework, we use a separate evidence-based interpreter named Highlighter to interpret the prediction model, which makes the prediction understandable and trustworthy to clinicians. We demonstrate that our approach achieves state-of-the-art performance in mortality prediction and can get an interpretable prediction on four different diseases
Considering Cumulative Risk for Cardiovascular Disease in Relation to Cognitive Function: a Comment on DeRight et al.
How should I treat a DES restenosis in a graft anastomosis with challenging access and multiple previous coronary interventions?
- …