12 research outputs found
Corrosivity monitoring database of kraft recovery boilers
"March 1998.""Submitted to 9th International Symposium on Corrosion in the Pulp and Paper Industry Ottawa, Ontario, Canada May 26-29, 1998.
An integrated microfluidic chip for studying the effects of neurotransmitters on neurospheroids
To improve our understanding of how the central nervous system functions in health and disease, we report the development of an integrated chip for studying the effects of the neurotransmitters dopamine and serotonin on adult rat hippocampal progenitor cell (AHPC) neurospheroids. This chip allows dopamine or serotonin located in one chamber to diffuse to AHPC neurospheroids cultured in an adjacent chamber through a built-in diffusion barrier created by an array of intentionally misaligned micropillars. The gaps among the micropillars are filled with porous poly(ethylene glycol) (PEG) gel to tune the permeability of the diffusion barrier. An electrochemical sensor is also integrated within the chamber where the neurospheroids can be cultured, thereby allowing monitoring of the concentrations of dopamine or serotonin. Experiments show that concentrations of the neurotransmitters inside the neurospheroid chamber can be increased over a period of several hours to over 10 days by controlling the compositions of the PEG gel inside the diffusion barrier. The AHPC neurospheroids cultured in the chip remain highly viable following dopamine or serotonin treatment. Cell proliferation and neuronal differentiation have also been observed following treatment, revealing that the AHPC neurospheroids are a valuable in vitro brain model for neurogenesis research. Finally, we show that by tuning the permeability of diffusion barrier, we can block transfer of Escherichia coli cells across the diffusion barrier, while allowing dopamine or serotonin to pass through. These results suggest the feasibility of using the chip to better understand the interactions between microbiota and brain via the gut–brain axis.This article is published as Mao, Subin, Catherine Fonder, Md Fazlay Rubby, Gregory J. Phillips, Donald S. Sakaguchi, and Long Que. "An integrated microfluidic chip for studying the effects of neurotransmitters on neurospheroids." Lab on a Chip 23, no. 6 (2023): 1649-1663. doi:10.1039/D2LC00755J. © The Royal Society of Chemistry 2023. This Open Access Article is licensed under a Creative Commons Attribution-Non Commercial 3.0 Unported Licence
Annual program review, corrosion control
"March 13, 1998."Recovery boiler corrosion / Preet M. Singh ... [et al.] ; Corrosion in closed cycle mills: project F019 / Preet M. Singh ... [et al.] -- Slide Material
Annual research review, corrosion control
"March 26, 1992."Recovery boiler corrosion: project 3628 / Jeff Colwell , Greg Fonder ; On the mechanism of corrosion of composite tubes at ports in kraft recovery boilers / Jeffery A. Colwell
Status report to the Corrosion Control Project Advisory Committee
"March 24, 1994."Recovery boiler corrosion: project 3628 / Jeffery A. Colwell , Gregory J. Fonder -- Slide Material
The effect of smelt/gas interaction on SA-210 carbon steel corrosion
"March 1998.""Submitted to 1998 International Chemical Recovery Conference Tampa, Florida June 1-4, 1998.
The effect of temperature excursion on sulfidation of carbon steel in 1% H2S environment
"March 1998.""Submitted to 9th International Symposium on Corrosion in the Pulp and Paper Industry Ottawa, Ontario, Canada, May 26-29, 1998.
Annual program review, corrosion control, March 8, 2000
"March 8, 2000."Project F018. Recovery boiler corrosion / Preet M. Singh ... [et al.] ; Project F019. Corrosion in closed cycle mills / Preet M. Singh Greg Fonder, Jamshad Mahmood ; Project F036. Mechanisms and prevention of stress-assisted waterside corrosion in recovery boilers / Preet Singh, Greg Fonder, Jamshad Mahmood ; Project F037. Corrosivity of black liquors / Preet Singh, Greg Fonder, Jamshad Mahmood -- Slide Material
Corrosion in kraft recovery boilers - in-situ characterization of corrosive environments
"July 1999.""Submitted to 1999 Engineering/Process and Product Quality Conference, September 12-16, Anaheim, California.
Annual program review, corrosion control
"March 21, 1996."Recovery boiler corrosion: project F018 / Greg Fonder ; Corrosivity monitoring in kraft recovery boilers / Preet Singh , Greg Fonder ; Smelt characterization for composite tube / H. Jeff Empie , Greg Fonder ; Hot corrosion in molten hydroxide / Matt Estes -- Slide Material