Unbalanced rearrangement der(9;18)(p10;q10) and JAK2 V617F mutation in a patient with AML following post-polycythemic myelofibrosis

Polycythemia Vera (PV) is a clonal myeloproliferative disorder characterized by excessive erythrocyte production, which may evolve into myelofibrosis and acute myeloid leukemia. Transformation to myelofibrosis occurs in 15-20% of cases and leukemic transformation in 5-10% of patients. The median survival time is 8-11 years and the median age at diagnosis is over 60 years. Normal karyotype is present at diagnosis in the majority of patients, while during transformation several acquired chromosome anomalies are present as trisomy 9 and gains in 9p

From Mare Nostrum to Mare Aliorum: Mediterranean Theory and Mediterraneism in Contemporary Italian Thought

This article surveys both the place of 'modern' Italy in the resurgence of Mediterranean Studies in the last decade and a half, and the contributions by Italian Studies and culture at large to the contemporary discourse on Mediterranean-ness. The author frames the discussion of recent scholarship by and about Italian Mediterranean-ness in a paradox: notwithstanding the role that 'Mare Nostrum' played in Italian identity construction and foreign policy (before, during and after Fascism), modern Italy is given very short shrift in current Mediterranean Studies. By contrast, over the past two to three decades 'Italy' has both confronted an unprecedented wave of immigration from the Mediterranean basin, and become almost synonymous with Mediterranen-ness in the global market of images. Responding to this paradox, the author argues, Italian scholars and intellectuals have been progressively transfiguring the Mediterranean from 'Mare Nostrum' (our sea) to 'Mare Aliorum' (the sea of the other)

To Measure Futurism

One of Futurism’s most consistent traits was its hostility to traditional intellectual culture: scholarship, academies, professors. Yet, Futurism also produced its own critical-intellectual products and scholarship in the form of misurazioni (theatrical measurements-reviews), commemorazioni in avanti (forward-looking commemorations), and collaudi (prefaces to futurist poetry collections). I analyze these intellectual products with an eye to both inserting them in the history of modernist ideas, and applying to them the futurist concept of “measurement” in order to highlight what was futurist in Futurism. The surprising result of this inquiry is that Futurism’s most lasting intellectual contribution may have been its multifaceted anti-dialectical idea of synthesis, which anticipated the encounter between cybernetics and eugenics in what Marinetti called a “bellissimo dopodomani” (beautiful day after tomorrow)