22 research outputs found
Editorial: New Themes in Analytic Dogmatic Theology
Analytic theology (AT) is a particular approach to theology and the study of religion that engages with the tools, categories, and methodological concerns of analytic philosophy. As a named-entity, AT arrived on the academic scene with the 2009 Oxford University Press publication, Analytic Theology: New Essays in the Philosophy of Theology, edited by Oliver D. Crisp and Michael C. Rea. AT was arguably represented, prior to this publication, by the proto-analytic theologian Richard Swinburne in his noteworthy works on Christian doctrine (e.g. Providence and the Problem of Evil, Responsibility and Atonement, The Christian God, Faith and Reason, and The Resurrection of God Incarnate), as well as by other professional philosophers of religion such as Alvin Plantinga, Nicholas Wolterstorff, Richard Swinburne, William Alston, Eleonore Stump, Robert and Marilyn McCord Adams, Basil Mitchell, Keith Yandell, Paul Helm, and Stephen T. Davis, among others. These philosophers were addressing such topics as the coherence of theism, the rationality of religious belief, and the contributions of such philosophical theologians of the medieval past including Thomas Aquinas or William Ockham and those from modernity including RenĂ© Descartes and Jonathan Edwards. Yet, the impetus for utilizing analytic philosophy to treat these topics emerged, not from the theological side of the conversation, but from the philosophical side. Anachronistically, then, the term âanalytic theologyâ seems to aptly describe the work of these philosophers of religion
Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTICâHF: baseline characteristics and comparison with contemporary clinical trials
Aims:
The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTICâHF) trial. Here we describe the baseline characteristics of participants in GALACTICâHF and how these compare with other contemporary trials.
Methods and Results:
Adults with established HFrEF, New York Heart Association functional class (NYHA)ââ„âII, EF â€35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokineticâguided dosing: 25, 37.5 or 50âmg bid). 8256 patients [male (79%), nonâwhite (22%), mean age 65âyears] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NTâproBNP 1971âpg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTICâHF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressureâ<â100âmmHg (n = 1127), estimated glomerular filtration rate <â30âmL/min/1.73 m2 (n = 528), and treated with sacubitrilâvalsartan at baseline (n = 1594).
Conclusions:
GALACTICâHF enrolled a wellâtreated, highârisk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation
De-Conditioning and Images of the Mind: Scientific Images and Dualistic Images
âDe-Conditioning and Images of the Mindâ explores the categories of Stephen Priest as developed in his article, âThe Unconditioned Soul.â Through an analysis of historical and contemporary examples of the âconditionedâ mode in recent philosophical and scientific discussions of the mind, the article articulates limitations of the proposed methods and advances examples of âde-conditioningâ the mind that point in the direction of what Priest calls the âunconditioned.
Reparative substitution and the âEfficacy Objectionâ:Toward a modified satisfaction theory of atonement
The doctrine of the atonement is a subject of perpetual curiosity for a number of contemporary theologians. The penal substitution theory of atonement in particular has precipitated a great deal of recent interest, being held up by many (mostly evangelical) Protestants as âtheâ doctrine of atonement. In this essay, we make a defense against the objection to the Anselmian theory of atonement that is often leveled against it by exponents of the Penal Substitution theory, namely, that Christâs work does not accomplish anything for those whom it appears he undertakes his atoning work, but merely makes provision for salvation
A Theology of Seeing, Experiencing, and Vision. An Editorial Introduction
What may seem astonishing is the near dismissal of the beatific vision doctrine in the last 50+ years of biblical and theological scholarship in contrast to the emphasis given to it throughout church history. The state of theological scholarship is changing. In what follows, we set forth a short survey of a theology of the beatific vision, while also introducing the rest of the volume on the beatific vision and theosis, of which we take to have an intimate and overlapping relationship. The editorial article has four parts: it begins by (1) introducing some of the relevant biblical material on the vision, proceeding to (2) develop a theological interpretation of those passages, and then (3) offer a short historical survey of the doctrine, focusing on the relevant medieval and Reformed developments. It finally (4) introduces the articles of the issue