The Transition Amplitude for 2T Physics

We present the transition amplitude for a particle moving in a space with two times and D space dimensions having a Sp(2,R) local symmetry and an SO(D,2) rigid symmetry. It was obtained from the BRST-BFV quantization with a unique gauge choice. We show that by constraining the initial and final points of this amplitude to lie on some hypersurface of the D+2 space the resulting amplitude reproduces well known systems in lower dimensions. This provides an alternative physical interpretation for two times physics which is derived in a single framework.Comment: 4 pages, typos corrected, references adde

Vacuum fluctuations in a supersymmetric model in FRW spacetime

We study a noninteracting supersymmetric model in an expanding FRW spacetime. A soft supersymmetry breaking induces a nonzero contribution to the vacuum energy density. A short distance cutoff of the order of Planck length provides a scale for the vacuum energy density comparable with the observed cosmological constant. Assuming the presence of a dark energy substance in addition to the vacuum fluctuations of the field an effective equation of state is derived in a selfconsistent approach. The effective equation of state is sensitive to the choice of the cut-off but no fine tuning is needed.Comment: 19 pages, accepted for publication in Phys. Rev.

Asymptotic Symmetries of Rindler Space at the Horizon and Null Infinity

We investigate the asymptotic symmetries of Rindler space at null infinity and at the event horizon using both systematic and ad hoc methods. We find that the approaches that yield infinite-dimensional asymptotic symmetry algebras in the case of anti-de Sitter and flat spaces only give a finite-dimensional algebra for Rindler space at null infinity. We calculate the charges corresponding to these symmetries and confirm that they are finite, conserved, and integrable, and that the algebra of charges gives a representation of the asymptotic symmetry algebra. We also use relaxed boundary conditions to find infinite-dimensional asymptotic symmetry algebras for Rindler space at null infinity and at the event horizon. We compute the charges corresponding to these symmetries and confirm that they are finite and integrable. We also determine sufficient conditions for the charges to be conserved on-shell, and for the charge algebra to give a representation of the asymptotic symmetry algebra. In all cases, we find that the central extension of the charge algebra is trivial.Comment: 37 pages, 4 figures. Version 3: New Section 5 adde

Neutrino oscillations in a Robertson-Walker Universe with space time foam

In Phys. Rev. D77 (2008) 105001, we have studied decoherence models for flavour oscillations in four-dimensional stochastically fluctuating space times and discussed briefly the sensitivity of current terrestrial and astrophysical neutrino experiments to such models. In this addendum we extend these results to incorporate the effects due to the expansion of the Universe, so that our analysis can be useful in studies of extragalactic high-energy neutrinos, such as those coming from Gamma Ray Bursts at cosmological distances. Unfortunately for some microscopic models of foam, constructed in the string theory framework, we arrive at pessimistic conclusions about the detectability of the decoherence effects via flavour oscillation meaurements.Comment: Addendum to Phys. Rev. D77 (2008) 10500

Spacetime Structure of an Evaporating Black Hole in Quantum Gravity

The impact of the leading quantum gravity effects on the dynamics of the Hawking evaporation process of a black hole is investigated. Its spacetime structure is described by a renormalization group improved Vaidya metric. Its event horizon, apparent horizon, and timelike limit surface are obtained taking the scale dependence of Newton's constant into account. The emergence of a quantum ergosphere is discussed. The final state of the evaporation process is a cold, Planck size remnant.Comment: 23 pages, BibTeX, revtex4, 7 figure

Accelerated Detectors and Temperature in (Anti) de Sitter Spaces

We show, in complete accord with the usual Rindler picture, that detectors with constant acceleration $a$ in de Sitter (dS) and Anti de Sitter (AdS) spaces with cosmological constants $\Lambda$ measure temperatures $2\pi T=(\Lambda/3+a^{2})^{1/2}\equiv a_{5}$, the detector "5-acceleration" in the embedding flat 5-space. For dS, this recovers a known result; in AdS, where $\Lambda$ is negative, the temperature is well defined down to the critical value $a_{5}=0$, again in accord with the underlying kinematics. The existence of a thermal spectrum is also demonstrated for a variety of candidate wave functions in AdS backgrounds.Comment: Latex +2 Fi

Flavour-Condensate-induced Breaking of Supersymmetry in Free Wess-Zumino Fluids

Recently we argued that a particular model of string-inspired quantum space-time foam (D-foam) may induce oscillations and mixing among flavoured particles. As a result, rather than the mass-eigenstate vacuum, the correct ground state to describe the underlying dynamics is the flavour vacuum, proposed some time ago by Blasone and Vitiello as a description of quantum field theories with mixing. At the microscopic level, the breaking of target-space supersymmetry is induced in our space-time foam model by the relative transverse motion of brane defects. Motivated by these results, we show that the flavour vacuum, introduced through an inequivalent representation of the canonical (anti-) commutation relations, provides a vehicle for the breaking of supersymmetry (SUSY) at a low-energy effective field theory level; on considering the flavour-vacuum expectation value of the energy-momentum tensor and comparing with the form of a perfect relativistic fluid, it is found that the bosonic sector contributes as dark energy while the fermion contribution is like dust. This indicates a strong and novel breaking of SUSY, of a non-perturbative nature, which may characterize the low energy field theory of certain quantum gravity models.Comment: Discussion added in sections II and IV on quantum-gravity induced flavour mixing, references added, conclusions unchange

Vacuum entanglement enhancement by a weak gravitational field

Separate regions in space are generally entangled, even in the vacuum state. It is known that this entanglement can be swapped to separated Unruh-DeWitt detectors, i.e., that the vacuum can serve as a source of entanglement. Here, we demonstrate that, in the presence of curvature, the amount of entanglement that Unruh-DeWitt detectors can extract from the vacuum can be increased.Comment: 6 pages, 1 figur

Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death

Sensing bacterial products in the cytosol of mammalian cells by NOD-like receptors leads to the activation of caspase-1 inflammasomes, and the production of the pro-inflammatory cytokines interleukin (IL)-18 and IL-1β. In addition, mouse caspase-11 (represented in humans by its orthologs, caspase-4 and caspase-5) detects cytosolic bacterial LPS directly. Activation of caspase-1 and caspase-11 initiates pyroptotic host cell death that releases potentially harmful bacteria from the nutrient-rich host cell cytosol into the extracellular environment. Here we use single cell analysis and time-lapse microscopy to identify a subpopulation of host cells, in which growth of cytosolic Salmonella Typhimurium is inhibited independently or prior to the onset of cell death. The enzymatic activities of caspase-1 and caspase-11 are required for growth inhibition in different cell types. Our results reveal that these proteases have important functions beyond the direct induction of pyroptosis and proinflammatory cytokine secretion in the control of growth and elimination of cytosolic bacteria

Contact Term, its Holographic Description in QCD and Dark Energy

In this work we study the well known contact term, which is the key element in resolving the so-called $U(1)_A$ problem in QCD. We study this term using the dual Holographic Description. We argue that in the dual picture the contact term is saturated by the D2 branes which can be interpreted as the tunnelling events in Minkowski space-time. We quote a number of direct lattice results supporting this identification. We also argue that the contact term receives a Casimir -like correction \sim (\Lqcd R)^{-1} rather than naively expected \exp(-\Lqcd R) when the Minkowski space-time ${\cal R}_{3,1}$ is replaced by a large but finite manifold with a size $R$. Such a behaviour is consistent with other QFT-based computations when power like corrections are due to nontrivial properties of topological sectors of the theory. In holographic description such a behaviour is due to massless Ramond-Ramond (RR) field living in the bulk of multidimensional space when power like corrections is a natural outcome of massless RR field. In many respects the phenomenon is similar to the Aharonov -Casher effect when the "modular electric field" can penetrate into a superconductor where the electric field is exponentially screened. The role of "modular operator" from Aharonov -Casher effect is played by large gauge transformation operator $\cal{T}$ in 4d QCD, resulting the transparency of the system to topologically nontrivial pure gauge configurations. We discuss some profound consequences of our findings. In particular, we speculate that a slow variation of the contact term in expanding universe might be the main source of the observed Dark Energy.Comment: Final version to appear in Phys. Rev. D. Comments added on interpretation of the "topological Casimir effect" from 5d viewpoint where it can be thought as conventional Casimir effec