On spontaneous photon emission in collapse models

We reanalyze the problem of spontaneous photon emission in collapse models. We show that the extra term found by Bassi and Duerr is present for non-white (colored) noise, but its coefficient is proportional to the zero frequency Fourier component of the noise. This leads one to suspect that the extra term is an artifact. When the calculation is repeated with the final electron in a wave packet and with the noise confined to a bounded region, the extra term vanishes in the limit of continuum state normalization. The result obtained by Fu and by Adler and Ramazanoglu from application of the Golden Rule is then recovered.Comment: 23 pages, LaTex. Minor changes with respect to previous versio

Entangling macroscopic diamonds at room temperature: Bounds on the continuous-spontaneous-localization parameters

A recent experiment [K. C. Lee et al., Science 334, 1253 (2011)] succeeded in detecting entanglement between two macroscopic specks of diamonds, separated by a macroscopic distance, at room temperature. This impressive results is a further confirmation of the validity of quantum theory in (at least parts of) the mesoscopic and macroscopic domain, and poses a challenge to collapse models, which predict a violation of the quantum superposition principle, which is the bigger the larger the system. We analyze the experiment in the light of such models. We will show that the bounds placed by experimental data are weaker than those coming from matter-wave interferometry and non-interferometric tests of collapse models.Comment: 7 pages, 3 figures, v2: close to the published version, LaTe

Are collapse models testable with quantum oscillating systems? The case of neutrinos, kaons, chiral molecules

Collapse models provide a theoretical framework for understanding how classical world emerges from quantum mechanics. Their dynamics preserves (practically) quantum linearity for microscopic systems, while it becomes strongly nonlinear when moving towards macroscopic scale. The conventional approach to test collapse models is to create spatial superpositions of mesoscopic systems and then examine the loss of interference, while environmental noises are engineered carefully. Here we investigate a different approach: We study systems that naturally oscillate --creating quantum superpositions-- and thus represent a natural case-study for testing quantum linearity: neutrinos, neutral mesons, and chiral molecules. We will show how spontaneous collapses affect their oscillatory behavior, and will compare them with environmental decoherence effects. We will show that, contrary to what previously predicted, collapse models cannot be tested with neutrinos. The effect is stronger for neutral mesons, but still beyond experimental reach. Instead, chiral molecules can offer promising candidates for testing collapse models.Comment: accepted by NATURE Scientific Reports, 12 pages, 1 figures, 2 table

The effect of spontaneous collapses on neutrino oscillations

We compute the effect of collapse models on neutrino oscillations. The effect of the collapse is to modify the evolution of the `spatial' part of the wave function, which indirectly amounts to a change on the flavor components. In many respects, this phenomenon is similar to neutrino propagation through matter. For the analysis we use the mass proportional CSL model, and perform the calculation to second order perturbation theory. As we will show, the CSL prediction is very small - mainly due to the very small mass of neutrinos - and practically undetectable.Comment: 24 pages, RevTeX. Updated versio

Early bisphosphonate treatment in infants with severe osteogenesis imperfecta.

Cyclical neridronate treatment, started just after diagnosis at birth, had positive effects on growth and fracture rat

Beyond quantum mechanics? Hunting the 'impossible' atoms (Pauli Exclusion Principle violation and spontaneous collapse of the wave function at test)

The development of mathematically complete and consistent models solving the so-called "measurement problem", strongly renewed the interest of the scientific community for the foundations of quantum mechanics, among these the Dynamical Reduction Models posses the unique characteristic to be experimentally testable. In the first part of the paper an upper limit on the reduction rate parameter of such models will be obtained, based on the analysis of the X-ray spectrum emitted by an isolated slab of germanium and measured by the IGEX experiment. The second part of the paper is devoted to present the results of the VIP (Violation of the Pauli exclusion principle) experiment and to describe its recent upgrade. The VIP experiment established a limit on the probability that the Pauli Exclusion Principle (PEP) is violated by electrons, using the very clean method of searching for PEP forbidden atomic transitions in copper

Spontaneously emitted X-rays: an experimental signature of the dynamical reduction models

We present the idea of searching for X-rays as a signature of the mechanism inducing the spontaneous collapse of the wave function. Such a signal is predicted by the continuous spontaneous localization theories, which are solving the "measurement problem" by modifying the Schrodinger equation. We will show some encouraging preliminary results and discuss future plans and strategy.Comment: to be published in Foundation of Physics 201

Promiscuous Gene Expression in the Thymus: The Root of Central Tolerance

The thymus is a complex organ with an epithelium formed by two main cell types, the cortical thymic epithelial (cTECs) and medullary thymic epithelial cells (mTECs), referred to as stroma. Immature thymocytes arising from the bone marrow, macrophages and dendritic cells also populate the thymus. Thymocytes evolve to mature T cells featuring cell differentiation antigens (CDs), which characterize the phenotypically distinct stages, defined as double-negative (DN), double positive (DP) and single positive (SP), based on expression of the coreceptors CD4 and CD8. The thymus is therefore implicated in T cell differentiation and during development into T cells thymocytes are in close association with the stroma. Recent evidence showed that mTECs express a diverse set of genes coding for parenchymal organ specific proteins. This phenomenon has been termed promiscuous gene expression (PGE) and has led to the reconsideration of the role of the thymus in central T cell tolerance to self-antigens, which prevents autoimmunity. The evidence of PGE is causing a reanalysis in the scope of central tolerance understanding. We summarize the evidence of PGE in the thymus, focusing particularly the use of cDNA microarray technology for the broad characterization of gene expression and demarcation of PGE emergence during thymus ontogeny

Experimental search for the "impossible atoms" Pauli Exclusion Principle violation and spontaneous collapse of the wave function at test

30siMany experiments investigated the possible violation of the Pauli Exclusion Principle (PEP) since its discovery in 1925. The VIP(Violation of the Pauli Principle) experiment tested the PEP by measuring the probability for an external electron to be captured and undergo a 2p to 1s transition during its cascading process, with the 1s state already occupied by two electrons. This transition is forbidden by the PEP. The VIP experiment resulted in an upper limit for the probability of PEP violation of 4.7×10−29. Currently a setup for the follow- up experiment VIP2 is under preparation. The goal of this experiment is to improve the upper limit for the violation of the PEP by two orders of magnitude, by using new X-ray detectors and by implementing an active shielding. We then present the idea of using an analogous experimental technique to search for X rays as a signature of the spontaneous collapse of the wave function, predicted by the continuous spontaneous localization theories, and discuss some very encouraging preliminary results.openopenCurceanu, C.; Bartalucci, S.; Bassi, A.; Bertolucci, S.; Berucci, C.; Bragadireanu, A.M.; Cargnelli, M.; Clozza, A.; De Paolis, L.; Di Matteo, S.; Donadi, S.; D'Uffizi, A.; Egger, J.-P.; Guaraldo, C.; Iliescu, M.; Ishiwatari, T.; Laubenstein, M.; Marton, J.; Milotti, E.; Pietreanu, D.; Piscicchia, K.; Ponta, T.; Sbardella, E.; Scordo, A.; Shi, H.; Sirghi, D.L.; Sirghi, F.; Sperandio, L.; Doce, O Vazquez; Zmeskal, J.Curceanu, C.; Bartalucci, S.; Bassi, Angelo; Bertolucci, S.; Berucci, C.; Bragadireanu, A. M.; Cargnelli, M.; Clozza, A.; De Paolis, L.; Di Matteo, S.; Donadi, Sandro; D'Uffizi, A.; Egger, J. P.; Guaraldo, C.; Iliescu, M.; Ishiwatari, T.; Laubenstein, M.; Marton, J.; Milotti, Edoardo; Pietreanu, D.; Piscicchia, K.; Ponta, T.; Sbardella, E.; Scordo, A.; Shi, H.; Sirghi, D. L.; Sirghi, F.; Sperandio, L.; Doce, O. Vazquez; Zmeskal, J