Monitoring and Control of Temperature in Networks-on-Chip

Increasing integration densities and the emergence of nanotechnology cause issues related to reliability and power consumption to become dominant factors for the design of modern multi-core systems. Since the arising problems are enforced by high circuit temperatures, monitoring and control of on-chip temperature profiles need to be considered during design phase as well as during system operation. Hence, in this paper different approaches for the realization and integration of a monitoring system for temperature in multi-core systems based on Networks-on-Chip (NoCs) in combination with Dynamic Frequency Scaling (DFS) are investigated. Results show that both combinations using event-driven and time-driven forwarding more than double overall execution time and considerably reduce throughput of application data. Regarding performance of notification and reaction to temperature development event-driven forwarding clearly outperforms time-driven forwarding

Cavity Disinfection With a 445 nm Diode Laser Within the Scope of Restorative Therapy – A Pilot Study

Introduction: Cavity disinfection is necessary to prevent a progressive infection of the crown dentin and pulp. Increasing intolerance and resistance to antiseptics and antibiotics as well as the controversy over the effects of those on the dental hard tissue and composite have prompted the investigation of alternative treatment options. The objective of this pilot study is to evaluate the antibacterial potential of a diode laser with a wavelength of 445 nm in the cavity preparation using the bacterium Streptococcus salivarius associated with caries in conjunction with the characteristics and influences of dentin on light transmission.Methods: The bactericidal effect of the laser irradiation was determined in culture experiments by using caries-free human dentin samples on bacteria-inoculated agar. For this, dentin discs (horizontally cut coronal dentin) of 500 μm and 1000 μm thicknesses were produced and irradiated with the laser with irradiation parameters of 0.7-1 W in a cw-mode and exposure times of between 5-30 s. Based on the different sample thicknesses, the penetration depth effect of the irradiation was ascertained after the subsequent incubation of the bacteria-inoculated agar. Additional influential parameters on the irradiation transmission were investigated, including surface moisture, tooth color as well as the presence of a smear layer on the dentin surface.Results: The optical transmission values of the laser radiation for dentin were significantly dependent on the sample thickness (P = 0.006) as well as its moisture content (P = 0.013) and were independent of the presence of a smear layer. There was a 40% reduction in bacteria after the radiography of the 500-μm-thick dentin samples, which was shown as the lowest laser dose (443 J/cm2).Conclusion: These findings indicate that the diode laser with light emission at a wavelength of 445 nm is interesting for the supportive cavity disinfection within the scope of caries therapy and show potential for clinical applications

Effective disease control

In South-Africa, communicable diseases are a major cause of livestock losses and it is disconcerting that so many preventable diseases still frequently result in substantial financial losses.http://www.dairyconnect.co.za/dairyMail

The effects of forest cover and disturbance on torrential hazards

Global human population growth, limited space for settlements and a booming tourism industry have led to a strong increase of human infrastructure in mountain regions. As this infrastructure is highly exposed to natural hazards, a main role of mountain forests is to regulate the environment and reduce hazard probability. However, canopy disturbances are increasing in many parts of the world, potentially threatening the protection function of forests. Yet, large-scale quantitative evidence on the influence of forest cover and disturbance on natural hazards remains scarce to date. Here we quantified the effects of forest cover and disturbance on the probability and frequency of torrential hazards for 10 885 watersheds in the Eastern Alps. Torrential hazard occurrences were derived from a comprehensive database documenting 3768 individual debris flow and flood events between 1986 and 2018. Forest disturbances were mapped from Landsat satellite time series analysis. We found evidence that forests reduce the probability of natural hazards, with a 25 percentage point increase in forest cover decreasing the probability of torrential hazards by 8.7%± 1.2%. Canopy disturbances generally increased the probability of torrential hazard events, with the regular occurrence of large disturbance events being the most detrimental disturbance regime for natural hazards. Disturbances had a bigger effect on debris flows than on flood events, and press disturbances were more detrimental than pulse disturbances. We here present the first large scale quantification of forest cover and disturbance effects on torrential hazards. Our findings highlight that forests constitute important green infrastructure in mountain landscapes, efficiently reducing the probability of natural hazards, but that increasing forest disturbances can weaken the protective function of forests.Austrian Climate Research ProgramAustrian Science Fund https://doi.org/10.13039/501100002428Peer Reviewe

Sodium Solid Electrolytes: NaxAlOy Bilayer-System Based on Macroporous Bulk Material and Dense Thin-Film

A new preparation concept of a partially porous solid-state bilayer electrolyte (BE) for high-temperature sodium-ion batteries has been developed. The porous layer provides mechanical strength and is infiltrated with liquid and highly conductive NaAlCl4 salt, while the dense layer prevents short circuits. Both layers consist, at least partially, of Na-β-alumina. The BEs are synthesized by a three-step procedure, including a sol-gel synthesis, the preparation of porous, calcined bulk material, and spin coating to deposit a dense layer. A detailed study is carried out to investigate the effect of polyethylene oxide (PEO) concentration on pore size and crystallization of the bulk material. The microstructure and crystallographic composition are verified for all steps via mercury intrusion, X-ray diffraction, and scanning electron microscopy. The porous bulk material exhibits an unprecedented open porosity for a NaxAlOy bilayer-system of ≤57% with a pore size of ≈200–300 nm and pore volume of ≤0.3 cm3∙g−1. It contains high shares of crystalline α-Al2O3 and Na-β-alumina. The BEs are characterized by impedance spectroscopy, which proved an increase of ionic conductivity with increasing porosity and increasing Na-β-alumina phase content in the bulk material. Ion conductivity of up to 0.10 S∙cm−1 at 300 °C is achieved

Monitoring and Control of Temperature in Networks-on-Chip

Abstract Increasing integration densities and the emergence of nanotechnology cause issues related to reliability and power consumption to become dominant factors for the design of modern multi-core systems. Since the arising problems are enforced by high circuit temperatures, monitoring and control of on-chip temperature profiles need to be considered during design phase as well as during system operation. Hence, in this paper different approaches for the realization and integration of a monitoring system for temperature in multi-core systems based on Networks-on-Chip (NoCs) in combination with Dynamic Frequency Scaling (DFS) are investigated. Results show that both combinations using event-driven and time-driven forwarding more than double overall execution time and considerably reduce throughput of application data. Regarding performance of notification and reaction to temperature development event-driven forwarding clearly outperforms time-driven forwarding

The effect of unrestricted milk feeding on the growth and health of Jersey calves

This study was conducted to determine the effect of feeding high milk volumes on the growth rate, health and cross-sucking behaviour in group-fed Jersey calves. Three-day-old heifers (n = 120) in a seasonal calving dairy herd were randomly assigned to one of 6 treatment groups. Three groups received high milk volumes (HMV), consisting of ad libitum milk or milk replacer feeding twice a day, while 3 groups received restricted milk volumes (RMV), consisting of 2 twice daily, during the pre-weaning period. After a pre-weaning period during which feeding was reduced to once daily, all calves were weaned at 42 days and monitored until 60 days of age.Adjusting for birth mass, birth date,damparity and sire, average daily mass gain (ADG), both pre-weaning (days 0–42) and overall (days 0–60), was higher inHMVthan inRMVcalves (P<0.001).After weaning, growth rates showed no differences and at 60 days of age the HMV calves maintained a 6.74 kg advantage in mean body mass (P < 0.001). The mean intake of dry starter feed was higher in RMV than in HMVcalves. Overall feed conversion rate ofHMVcalves was 9.6%better thanRMVcalves. However, the variable cost per kg mass gain was 12 % higher for HMV calves. In the RMV groups 75 % of calves showed cross-sucking behaviour pre-weaning and 18 % post-weaning, whereas in HMV calves the proportions were 2 % and 7 %, respectively. There was no significant effect of milk volume on the incidence of diarrhoea.We conclude that the feeding of high volumes of milk to Jersey calves has a positive effect on growth rate, without compromising health or reducing solid feed intake after weaning. However, the higher cost of such a feeding system may limit its implementation.http://www.journals.co.za/ej/ejour_savet.htm

The structural basis of proton driven zinc transport by ZntB

Zinc is an essential microelement to sustain all forms of life. However, excess of zinc is toxic, therefore dedicated import, export and storage proteins for tight regulation of the zinc concentration have evolved. In Enterobacteriaceae, several membrane transporters are involved in zinc homeostasis and linked to virulence. ZntB has been proposed to play a role in the export of zinc, but the transport mechanism of ZntB is poorly understood and based only on experimental characterization of its distant homologue CorA magnesium channel. Here, we report the cryo-electron microscopy structure of full-length ZntB from Escherichia coli together with the results of isothermal titration calorimetry, and radio-ligand uptake and fluorescent transport assays on ZntB reconstituted into liposomes. Our results show that ZntB mediates Zn2+ uptake, stimulated by a pH gradient across the membrane, using a transport mechanism that does not resemble the one proposed for homologous CorA channels

The effect of cow-level factors on colostrum quality, passive immunity and health of neonatal calves in a pasture-based dairy operation

A study of 95 cows (19 primiparous and 76 multiparous) and their offspring was performed on a pasture-based dairy in the coastal region of South Africa. Collected data included weight changes during the dry period, colostrum immunoglobulin G (IgG) and calf serum IgG at 24–48 h after birth. Colostrum and serum IgG concentrations were measured using radial immunodiffusion and colostrum was regarded as having adequate IgG concentration if the amount was 50 g/L. Calf serum IgG concentration of 10 g/L was considered an adequate transfer of passive immunity. The median (range in parentheses) colostrum quality for cows with weight loss during the dry period was 23.1 g/L (9.0, 108.1) compared with 61.9 g/L (10.9, 200.0) in cows without weight loss. The median serum IgG of calves from cows with weight loss was 9.9 g/L (0.5, 44.6) compared with 14.0 g/L (0.5, 76.3) in calves from cows that did not lose weight during the dry period. Cows experiencing weight loss were four times more likely to have colostrum with lower concentrations of IgG (OR = 0.25; 95% CI, 0.07–0.88; P = 0.030). Lactation number was also significantly associated with colostrum IgG concentration (P < 0.001), with younger cows tending to have higher IgG concentrations. Failure of passive transfer did not have a significant effect on any calf-health or production variables measured in the study. The effect of dry-cow feeding on colostrum IgG concentration is poorly understood and inadequate pasture management could have an impact on colostrum quality in pasture-based dairy herds.The University of Pretoria and the National Research Foundation (NRF) of South Africa (Grant No. 76734).http://www.publish.csiro.au/anhj2018Production Animal Studie