2,604,125 research outputs found

    Visual Culture Analysis of The Last Ditch of the Chivalry, or a President in Petticoats

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    This lithograph is a Northern depiction of the capture of former Confederate President Jefferson Davis. Titled The Last Ditch of the Chivalry, or a President in Petticoats , and picturing Davis in a woman’s dress and bonnet, the Northern press painted Davis as a coward. Rather than being a man and standing up to the Union troops, Davis disguised himself as a woman and attempted to cowardly escape. Although in actuality Davis was wearing a rain jacket and shawl rather than a full dress and bonnet, the Northern press mocked him. This piece demonstrates the prominence of male Southern honor, and how the ideals of being a man contradicted with the expectations for women. Davis’ flee also symbolizes the fall of the Confederacy

    Attachment Styles Within the Coach-Athlete Dyad: Preliminary Investigation and Assessment Development

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    The present preliminary study aimed to develop and examine the psychometric properties of a new sport-specific self-report instrument designed to assess athletes’ and coaches’ attachment styles. The development and initial validation comprised three main phases. In Phase 1, a pool of items was generated based on pre-existing self-report attachment instruments, modified to reflect a coach and an athlete’s style of attachment. In Phase 2, the content validity of the items was assessed by a panel of experts. A final scale was developed and administered to 405 coaches and 298 athletes (N = 703 participants). In Phase 3, confirmatory factor analysis of the obtained data was conducted to determine the final items of the Coach-Athlete Attachment Scale (CAAS). Confirmatory factor analysis revealed acceptable goodness of fit indexes for a 3-first order factor model as well as a 2-first order factor model for both the athlete and the coach data, respectively. A secure attachment style positively predicted relationship satisfaction, while an insecure attachment style was a negative predictor of relationship satisfaction. The CAAS revealed initial psychometric properties of content, factorial, and predictive validity, as well as reliability

    Mutations of the BRAF gene in human cancer

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    Cancers arise owing to the accumulation of mutations in critical genes that alter normal programmes of cell proliferation, differentiation and death. As the first stage of a systematic genome-wide screen for these genes, we have prioritized for analysis signalling pathways in which at least one gene is mutated in human cancer. The RAS RAF MEK ERK MAP kinase pathway mediates cellular responses to growth signals. RAS is mutated to an oncogenic form in about 15% of human cancer. The three RAF genes code for cytoplasmic serine/threonine kinases that are regulated by binding RAS. Here we report BRAF somatic missense mutations in 66% of malignant melanomas and at lower frequency in a wide range of human cancers. All mutations are within the kinase domain, with a single substitution (V599E) accounting for 80%. Mutated BRAF proteins have elevated kinase activity and are transforming in NIH3T3 cells. Furthermore, RAS function is not required for the growth of cancer cell lines with the V599E mutation. As BRAF is a serine/threonine kinase that is commonly activated by somatic point mutation in human cancer, it may provide new therapeutic opportunities in malignant melanoma

    Layton, Thomas N.

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    University of California, Davis, B.A. 1965 University of California, Davis, M.A. 1966 Harvard University, Anthropology, Ph.D. 1971https://scholarworks.sjsu.edu/erfa_bios/1276/thumbnail.jp

    Left Behind: How the Absence of a Federal Vacatur Law Disadvantages Survivors of Human Trafficking

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    After a hamstring injury in October of 2004 forced her to surrender her athletic scholarship at St. John\u27s University, Shamere McKenzie chose to spend her winter break working in order to save the money she needed to pay the remainder of her tuition. In January of 2005, Shamere met a man named Corey Davis, who expressed an interest in dating her. After getting to know him for several weeks, she eventually shared with him the challenges she was having earning the money she needed to continue her enrollment in college. Davis encouraged her to consider exotic dancing as a way to earn quick money, and told her he would act as her protection from the men in theclubs. Desperate to return to school and put at ease by Davis\u27s charming and intelligent demeanor, Shamere accepted his offer.Shamere became even more convinced of the sincerity of Davis\u27s promises after making $300 in less than two hours on her first night in a New Jersey strip club. Energized by the prospect of making the money she needed far more quickly than she had anticipated, Shamere accepted Davis\u27s offer to travel from the club to a house party in Brooklyn where she could earn additional income by dancing for the men in attendance. When one of the men at the house requested a sex act from her, Shamere spoke harshly to him, which Davis overheard. Instead of protecting her as she expected he would, Davis pulled Shamere to the side and demanded she do as the man requested. When she protested, Davis told her that if she tried to leave, he\u27d make sure she never made it out alive. Later that night, he threatened to kill Shamere\u27s family if she disobeyed him again, then choked her to the point of unconsciousness

    \u3cem\u3eUnited States v. The William\u3c/em\u3e and The Phenomena of Jury Nullification in Early 19th Century America

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    In September 1808, Judge John Davis upheld the constitutionality of the Embargo Act of 1807 under the Constitution’s Article I, Section 8, Clause 3 Interstate Commerce power. Judge Davis’s original opinion curiously lacks any reference to Marbury v. Madison. Judge Davis defends judicial review and rejects the notion of jury nullification. While Judge Davis upheld the embargo’s constitutionality, a subsequent jury trial on the facts resulted in the return of The William to its rightful owners. This case reflects the attempts by early American judges to carve out the power of judicial review and maintain the appearance of an impartial judiciary
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