METABOLIC SYNDROME INCIDENCE IN WOMEN WITH PREVIOUS GESTATIONAL DIABETES MELLITUS

Ovo istraživanje je napravljeno sa svrhom istraživanja učestalosti dijabetesa i faktora povezanih s dijabetesom kod žena pet godina nakon trudnoće opterećene gestacijskim dijabetesom (GDM). Sve žene (N=90) čiji je gestacijski dijabetes bio klasificiran po kriterijima Svjetske Zdravstvene Organizacije (SZO) su rodile živu djecu. Nad svih 90 žena je u svrhu kontrole nakon 5 godina provođen dvosatni test oralnog opterećenja glukozom te je učinjena detaljna antropometrija. Pri dijagnosticiranju dijabetesa korišteni su kriteriji SZO, a za metabolički sindrom kriteriji IDM-a tj. preporuke za žene iz Europe. U ovom istraživanju incidencija dijabetesa je bila 7.8%, te metaboličkog sindroma 42%. Žene s metaboličkim sindromom su imale veći omjer struk bokovi, kožne nabore, indeks tjelesne mase i višu vrijednost koncentracije glukoze natašte. Naši rezultati upućuju velik rizik nastanka dijabetesa i metaboličkog sindroma u žena s prethodnim gestacijskim dijabetesom. Praćenje ovih žena nakon poroda bi pružilo mogućnost promjene nepovoljnih životnih navika.This study was carried out to examine the incidence of diabetes and the factors associated with them in women five years after they were examined for gestational diabetes (GDM). Women (N=90) whose GDM status was determined (WHO criteria) delivered live babies. Of these, 90 women available for follow-up after 5 years underwent a 2-hour oral glucose tolerance test and detailed anthropometry. Diabetes was determined using WHO criteria, and metabolic syndrome using IDF criteria recommended for European women. The incidence of diabetes was 7.8% and metabolic syndrome 42%. Women with MS had larger waist-to-hip ratio, skinfolds, body mass index and higer FPG (fasting plasma glucose). Our findings suggest high diabetes and cardiovascular risks in women with previous GDM. Follow-up of these women after delivery would provide opportunities to modify adverse lifestyle factors

Birth Weight of Healthy Newborns in Zagreb Area, Croatia

The aim of this study was to assess birth weight of healthy newborns from the City of Zagreb and Zagreb County, Croatia. Birth weights of healthy newborns, born at the Department of Obstetrics and Gynecology, University Hospital Center »Zagreb« in the year 2001, were included into analysis. Since there were only few newborns in the 22nd–27th week of gestation, they were excluded from the study. Small number of data points was also noticed in 28th–36th week of gestation, and was supplemented with the data from the years 2000, 2002 and 2003. The method of analysis used in this study was described by Altman and Chitty (Br. J. Obstet. Gynaecol., 101 (1994) 29). After the application of well defined exclusion criteria, the final sample consisted of 4,252 newborns. Percentile values for the four groups of newborns (male gender–primipara, male gender–multipara, female gender–primipara, female gender–multipara) were defined, yielding highest birth weight values in the male gender–multipara group (50th percentile of 40th gestational week was 3551.3 g), while female gender–primipara newborns were the lightest among the four sub-samples studied (50th percentile of 40th gestational week was 3399.9 g). New percentile values for percentile curves plotting are presented here and recommended for use in the clinical practice