Twist-3 contribution to the pion electromagnetic form factor

Non-leading contribution to the pion electromagnetic form factor which comes from the pion twist-3 wave function is analyzed in the modified hard scattering approach (MHSA) proposed by Li and Sterman. This contribution is enhanced significantly due to bound state effect (the twist-3 wave function is independent of the fractional momentum carried by the parton and has a large factor $\sim m_\pi^2/m_0$ with $m_\pi$ being the pion meson mass and $m_0$ being the mean u- and d-quark masses). Consequently, although it is suppressed by the factor $1/Q^2$, the twist-3 contribution is comparable with and even larger than the leading twist (twist-2) contribution at intermediate energy region of $Q^2$ being $2 \sim 40 {GeV}^2$.Comment: 10 pages, 2 fgures, latex. More discussions on the Sudakov effect added, references added. To appear in European Physical Journal C (Zeitschrift fur Physik C

On the Nature of X(4260)

We study the property of $X(4260)$ resonance by re-analyzing all experimental data available, especially the $e^+e^- \rightarrow J/\psi\,\pi^+\pi^-,\,\,\,\omega\chi_{c0}$ cross section data. The final state interactions of the $\pi\pi$, $K\bar K$ couple channel system are also taken into account. A sizable coupling between the $X(4260)$ and $\omega\chi_{c0}$ is found. The inclusion of the $\omega\chi_{c0}$ data indicates a small value of $\Gamma_{e^+e^-}=23.30\pm 3.55$eV.Comment: Refined analysis with new experimental data included. 13 page

Functional analysis of human hyaluronan synthase 3 splicing variant 2

Hyaluronan is a large glycosaminoglycan mainly presented in the extracellular matrix as well as in the intracellular compartment. Hyaluronan is synthesized by three hyaluronan synthase isoforms, namely HAS1, HAS2 and HAS3. HAS3v2 is a smaller splicing variant of HAS3 with 281 AA in length. Here, biological and pathological functions of HAS3v2 were investigated for the first time. HAS3v2 localizes on membrane of the endoplasmic reticulum as shown by stable overpression of YFP-HAS3v2 fusion protein. Overexpression of HAS3v2 leads to increased intracellular hyaluronan. A HA-HAS3v2 complex was also detected in microsomes of YFP-HAS3v2 overexpressing cells using the HAS enzymatic capture assay. This indicated HAS3v2 is an intracellular hyaluronan synthase or at least HA binding protein. Esophageal cancer is one of the 10 most frequent tumor types worldwide, which is distinguished into two major subtypes: squamous cell carcinoma (ESCC) and adenocarcinoma (EAC). HAS3v2 is upregulated only in human EAC and also correlated with TNM staging. This suggested that HAS3v2 is a potential tumor marker for EAC. Lentiviral overexpression of HAS3v2 promotes cell proliferation rate both in vitro and after xenografting of HAS3v2 overexpressing EAC cells in nude mice . This phenotype was, at least partially, caused by enhanced ERK1/2 kinase phosphorylation. HAS3v2 also stimulated the phosphorylation of focal adhesion kinase (FAK) and improve EAC cell adhesion. Both phosphorylations could be the consequence of activated RHAMM signaling. Overexpression of HAS3v2 in cancer cells also stimulated HAS3v1 mRNA expression in stromal cells of EAC xenograft, which led to increased stromal HA levels. The stromal HA has been reported to provide microenvironment in favor for progression and metastasis. The expression of HAS3v2 in EAC was regulated by EGF pathway and the blocking antibody of EGFR, Cetuximab, diminished the EGF-induced HAS3v2 upregulation. Furthermore, the mRNA expression of HAS3v2 and EGFR are positively correlated in EAC patients. Taken together, HAS3v2 promotes malignant tumor cell phenotype and could be a diagnostic oncogene and a potential therapeutic target for EAC

Uniform Moment Bounds for Generalized Jackson Networks in Multi-scale Heavy Traffic

We establish uniform moment bounds for steady-state queue lengths of generalized Jackson networks (GJNs) in multi-scale heavy traffic as recently proposed by Dai et al. [2023]. Uniform moment bounds lay the foundation for further analysis of the limit stationary distribution. Our result can be used to verify the crucial moment state space collapse (SSC) assumption in Dai et al. [2023] to establish a product-form limit of GJN in the multi-scale heavy traffic regime. Our proof critically utilizes the Palm version of the basic adjoint relationship (BAR) as developed in Braverman et al. [2023]

Cyclic inequivalence of cascaded GMW-sequences

AbstractCascaded GMW sequences have two-level autocorrelation functions, which have important applications in communications and cryptology. In this paper, we consider the cascaded GMW sequences corresponding to a fixed finite chain of finite fields, and determine whether the different cascaded GMW sequences are cyclically inequivalent. By introducing the so-called restricted integer systems (RISs), it is proved that all the cascaded GMW sequences can be determined by means of the RISs, and the sequences determined by different RISs are different. Moreover, different cascaded GMW sequences are cyclically inequivalent