16 research outputs found
Molecular interactions between Hel2 and RNA supporting ribosome-associated quality control
Get PDFRibosome-associated quality control (RQC) pathways monitor and respond to stalling of the translating ribosome. Here the authors show that the ribosome associated RQC factor Hel2/ZNF598, an E3 ubiquitin ligase, generally interacts with mRNAs in the vicinity of stop codons
Human Coding Synonymous Single Nucleotide Polymorphisms at Ramp Regions of mRNA Translation
No full textInhibiting K63 Polyubiquitination Abolishes No-Go Type Stalled Translation Surveillance in Saccharomyces cerevisiae
No full text
Changes in global translation elongation or initiation rates shape the proteome via the Kozak sequence
No full text
No-Go Decay mRNA cleavage in the ribosome exit tunnel produces 5′-OH ends phosphorylated by Trl1
No full textThe E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs
No full textUnderstanding Biases in Ribosome Profiling Experiments Reveals Signatures of Translation Dynamics in Yeast
No full text
