Application of HPLC-APCI-MS for sensitive determination of bioactive amines in fish-based food products intended for infants and young children

The presence of bioactive amines (BA) such as putrescine (PUT), cadaverine (CAD), histamine (HIS), tyramine (TYR), spermidine (SPD) and spermine (SPM) in food products intended for infants and young children should be analysed and controlled in respect to their direct (HIS, TYR) or potential toxicity properties (SPD, SPM). The aim of this work was to evaluate the selected bioactive amines content in fish-based food products intended for infants and young children using optimized HPLC-APCI-MS method