205 research outputs found
Recommended from our members
Is Cognitive Science Truly Interdisciplinary?: The Case of Interdisciplinary Collaborations
The field of cognitive science is inherently multi?disciplinary. However, it is unclear to what extent truly
interdisciplinary work occurs in cognitive science. That is,
is cognitive science merely a collection of researchers from
different disciplines working separately on commo n
problems? Data gathered from a recent cognitive science
conference are presented. Interestingly, a significant
proportion of interdisciplinary collaborations were found.
Analyses were also conducted on the impact of same vs.
different backgrounds on the structure of collaborations,
and It was found that interdisciplinary collaborations
involved more equally distributed contributions among the
authors than did intradisciplinary collaborations
Brain responses to biological motion predict treatment outcome in young children with autism
Autism spectrum disorders (ASDs) are common yet complex neurodevelopmental disorders, characterized by social, communication and behavioral deficits. Behavioral interventions have shown favorable results—however, the promise of precision medicine in ASD is hampered by a lack of sensitive, objective neurobiological markers (neurobiomarkers) to identify subgroups of young children likely to respond to specific treatments. Such neurobiomarkers are essential because early childhood provides a sensitive window of opportunity for intervention, while unsuccessful intervention is costly to children, families and society. In young children with ASD, we show that functional magnetic resonance imaging-based stratification neurobiomarkers accurately predict responses to an evidence-based behavioral treatment—pivotal response treatment. Neural predictors were identified in the pretreatment levels of activity in response to biological vs scrambled motion in the neural circuits that support social information processing (superior temporal sulcus, fusiform gyrus, amygdala, inferior parietal cortex and superior parietal lobule) and social motivation/reward (orbitofrontal cortex, insula, putamen, pallidum and ventral striatum). The predictive value of our findings for individual children with ASD was supported by a multivariate pattern analysis with cross validation. Predicting who will respond to a particular treatment for ASD, we believe the current findings mark the very first evidence of prediction/stratification biomarkers in young children with ASD. The implications of the findings are far reaching and should greatly accelerate progress toward more precise and effective treatments for core deficits in ASD
On Lagrangian Coherent Structures in Laparoscopy
Laparoscopy is an electrosurgical medical operation often involving an
application of high-frequency alternating current to remove undesired
biological tissue from the insufflated abdomen accessible through inlet and
outlets trocars. One of the main byproducts in this process are the gaseous
particles, called surgical smoke, which is found hazardous for both the patient
and the operating room staff. The elimination of this hazardous material is an
area of active research in the medical community. Thus, understanding dynamics
influenced by the underlying flow inside the abdomen is crucial. In this
article, we propose a computational fluid dynamics model and analyse the
velocity field in an insufflated abdomen shaped domain by identifying the
Lagrangian Coherent Structures (LCS) that are responsible for the
transportation, mixing and accumulation of the material particles in the flow.
By calculating the mixing strength we show that the regions revealed by these
material curves are dependent on the angle, positions and number of the outlets
and inlets. Hence, a novel utility of LCS in medical surgery is presented that
can detail the dynamics of surgical smoke informing better design of effective
smoke removal technologies
Results from the Atacama B-mode Search (ABS) Experiment
The Atacama B-mode Search (ABS) is an experiment designed to measure cosmic
microwave background (CMB) polarization at large angular scales (). It
operated from the ACT site at 5190~m elevation in northern Chile at 145 GHz
with a net sensitivity (NEQ) of 41 K. It employed an
ambient-temperature sapphire half-wave plate rotating at 2.55 Hz to modulate
the incident polarization signal and reduce systematic effects. We report here
on the analysis of data from a 2400 deg patch of sky centered at
declination and right ascension . We perform a blind
analysis. After unblinding, we find agreement with the Planck TE and EE
measurements on the same region of sky. We marginally detect polarized dust
emission and give an upper limit on the tensor-to-scalar ratio of (95%
cl) with the equivalent of 100 on-sky days of observation. We also present a
new measurement of the polarization of Tau A and introduce new methods
associated with HWP-based observations.Comment: 38 pages, 11 figure
- …