Defects and disorder in metal organic frameworks

International audienceThe wide-ranging properties of metal organic frameworks (MOFs) rely in many cases on the presence of defects within their structures and the disorder that is inevitably associated with such defects. In the present work we review several aspects of defects in MOFs, ranging from simple substitutional defects at metal cation or ligand positions, to correlated defects on a larger length scale and the extreme case of disorder associated with amorphous MOFs. We consider both porous and dense MOFs, and focus particularly on the way in which defects and disorder can be used to tune physical properties such as gas adsorption, catalysis, photoluminescence, and electronic and mechanical properties

Defects and disorder in metal organic frameworks.

The wide-ranging properties of metal organic frameworks (MOFs) rely in many cases on the presence of defects within their structures and the disorder that is inevitably associated with such defects. In the present work we review several aspects of defects in MOFs, ranging from simple substitutional defects at metal cation or ligand positions, to correlated defects on a larger length scale and the extreme case of disorder associated with amorphous MOFs. We consider both porous and dense MOFs, and focus particularly on the way in which defects and disorder can be used to tune physical properties such as gas adsorption, catalysis, photoluminescence, and electronic and mechanical properties.The authors would like to thank Ras Al Khaimah Center for Advanced Materials (AKC, TDB), Trinity Hall (TDB), and the ERC (ALG, Grant 279705).This is the author accepted manuscript. The final version is available from RSC via http://dx.doi.org/10.1039/C5DT04392

Machine learning for improved pathological staging of prostate cancer : A performance comparison on a range of classifiers

Peer reviewedPostprin

Can Thermoclines Be a Cue to Prey Distribution for Marine Top Predators? A Case Study with Little Penguins

The use of top predators as bio-platforms is a modern approach to understanding how physical changes in the environment may influence their foraging success. This study examined if the presence of thermoclines could be a reliable signal of resource availability for a marine top predator, the little penguin (Eudyptula minor). We studied weekly foraging activity of 43 breeding individual penguins equipped with accelerometers. These loggers also recorded water temperature, which we used to detect changes in thermal characteristics of their foraging zone over 5 weeks during the penguin’s guard phase. Data showed the thermocline was detected in the first 3 weeks of the study, which coincided with higher foraging efficiency. When a thermocline was not detected in the last two weeks, foraging efficiency decreased as well. We suggest that thermoclines can represent temporary markers of enhanced food availability for this top-predator to which they must optimally adjust their breeding cycle

Mise au point d'une méthode de titrage du virus aphteux sur le porc

Thomas J. P., Fédida Maurice, Coudert Michel, Dannacher Guy, Peillon Myriam, Lucam François. Mise au point d’une méthode de titrage du virus aphteux sur le porc. In: Bulletin de l'Académie Vétérinaire de France tome 124 n°7, 1971. pp. 353-357

L’immunité anti-aphteuse chez le porc vacciné. II. Appréciation par titrage des anticorps

Fédida Maurice, Dannacher Guy, Coudert Michel, Peillon Myriam, Thomas J.-P., Lucam François. L'immunité anti-aphteuse chez le Porc vacciné. II. Appréciation par titrage des anticorps. In: Bulletin de l'Académie Vétérinaire de France tome 124 n°8, 1971. pp. 387-392

L'immunité anti-aphteuse chez le porc vacciné. I. Mise au point d'une méthode d'appréciation par épreuve virulente

Fédida Maurice, Dannacher Guy, Coudert Michel, Peillon Myriam, Thomas J.-P., Lucam François. L’immunité anti-aphteuse chez le Porc vacciné. I. Mise au point d’une méthode d’appréciation par épreuve virulente. In: Bulletin de l'Académie Vétérinaire de France tome 124 n°8, 1971. pp. 381-386

Expression and regulation of the Msx1 natural antisense transcript during development

Bidirectional transcription, leading to the expression of an antisense (AS) RNA partially complementary to the protein coding sense (S) RNA, is an emerging subject in mammals and has been associated with various processes such as RNA interference, imprinting and transcription inhibition. Homeobox genes do not escape this bidirectional transcription, raising the possibility that such AS transcription occurs during embryonic development and may be involved in the complexity of regulation of homeobox gene expression. According to the importance of the Msx1 homeobox gene function in craniofacial development, especially in tooth development, the expression and regulation of its recently identified AS transcripts were investigated in vivo in mouse from E9.5 embryo to newborn, and compared with the S transcript and the encoded protein expression pattern and regulation. The spatial and temporal expression patterns of S, AS transcripts and protein are consistent with a role of AS RNA in the regulation of Msx1 expression in timely controlled developmental sites. Epithelial–mesenchymal interactions were shown to control the spatial organization of S and also AS RNA expression during early patterning of incisors and molars in the odontogenic mesenchyme. To conclude, this study clearly identifies the Msx1 AS RNA involvement during tooth development and evidences a new degree of complexity in craniofacial developmental biology: the implication of endogenous AS RNAs