9 research outputs found
Nutrient Removal from Recirculating Aquaculture System Water
- Author
- Publication venue
- DigitalCommons@UMaine
- Publication date
- 19/08/2022
- Field of study
Get PDFRecirculating aquaculture systems (RAS), where only approximately 10% of the total system water is exchanged per day, have grown in popularity in recent years due to their potential to provide a high-quality protein source in a contained environment. With increased production comes the need for RAS water treatment to mitigate recirculation and discharge of nutrients produced by fish; mainly phosphorus and nitrogen. When discharged, nutrients can contribute to eutrophication in surrounding water bodies, harming the fish and other aquatic life. Therefore, RAS effluent should be treated before discharge. One method of phosphorus removal is adsorption, a surface phenomenon that is often used to bind dissolved pollutants to a solid-phase medium and remove them from water. Nitrogen is present in RAS as ammonia, which is toxic to fish even at concentrations as low as 0.05 mg L-1. Therefore, the ammonia is transformed to nitrogen’s non-toxic form, nitrate, before recirculation or discharge, by a process called nitrification. Both adsorption and nitrification can be affected by RAS process parameters such as salinity. Many anadromous fish such as Atlantic salmon require a change in salinity over their lifetimes; therefore, both of these processes should be investigated for their response to salinity changes.
An adsorption study was performed on an aluminum oxide-based material, RhizoSorb®, to assess its response to different RAS variables. It was found that both film diffusion and intraparticle diffusion are rate-controlling steps in the adsorption process, and the removal efficiencies in batch tests were affected by time, salinity, and phosphate concentration. The Freundlich isotherm fit the equilibrium data better than the Langmuir isotherm, showing that adsorption is a multi-layer process and that the adsorbent is highly heterogeneous. The Clark model was better suited than the Thomas model for predicting the performance of the RhizoSorb® in a flow-through system. The results of this study showed that RhizoSorb® and other alumina-based sorbents have high potential towards application to the RAS water treatment process to remove and recover phosphorus.
A second study was performed to assess the effects of salinity changes on nitrifying biofilters. Acclimation to a small amount of salinity before transition to a higher salinity may help biofilters recover from the larger shift; therefore, a series of experiments was performed on both freshwater and brackish (3 parts per thousand (ppt)) biofilters to assess their respective levels of recovery after an abrupt change in salinity (3, 20, and 33 ppt). Tests were run for a two-week period in which the nitrification rates were monitored. The freshwater biofilters quickly recovered from a shift to 3 ppt, but did not recover from a shift to 20 or 33 ppt. The brackish filters started to recover at the end of the two-week test, but did not recover from a shift to 33 ppt. DNA sequencing of the variable V4 region of the 16s rRNA gene showed that the heterotrophic communities in the biofilm were lysed at a greater proportion than the nitrifiers, though the nitrifiers were inactivated in higher salinities. A longer series of tests could fully characterize the effects of acclimation to salinity with the effects of ammonia concentration and organic matter, which could help to fully understand the microbial community dynamics
Thrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry
- Author
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- Publication venue
- Publication date
- 01/01/2023
- Field of study
No full textBackground: COVID-19 has been associated with a broad range of thromboembolic, ischemic, and hemorrhagic complications (coagulopathy complications). Most studies have focused on patients with severe disease from high-income countries (HICs). Objectives: The main aims were to compare the frequency of coagulopathy complications in developing countries (low- and middle-income countries [LMICs]) with those in HICs, delineate the frequency across a range of treatment levels, and determine associations with in-hospital mortality. Methods: Adult patients enrolled in an observational, multinational registry, the International Severe Acute Respiratory and Emerging Infections COVID-19 study, between January 1, 2020, and September 15, 2021, met inclusion criteria, including admission to a hospital for laboratory-confirmed, acute COVID-19 and data on complications and survival. The advanced-treatment cohort received care, such as admission to the intensive care unit, mechanical ventilation, or inotropes or vasopressors; the basic-treatment cohort did not receive any of these interventions. Results: The study population included 495,682 patients from 52 countries, with 63% from LMICs and 85% in the basic treatment cohort. The frequency of coagulopathy complications was higher in HICs (0.76%-3.4%) than in LMICs (0.09%-1.22%). Complications were more frequent in the advanced-treatment cohort than in the basic-treatment cohort. Coagulopathy complications were associated with increased in-hospital mortality (odds ratio, 1.58; 95% CI, 1.52-1.64). The increased mortality associated with these complications was higher in LMICs (58.5%) than in HICs (35.4%). After controlling for coagulopathy complications, treatment intensity, and multiple other factors, the mortality was higher among patients in LMICs than among patients in HICs (odds ratio, 1.45; 95% CI, 1.39-1.51). Conclusion: In a large, international registry of patients hospitalized for COVID-19, coagulopathy complications were more frequent in HICs than in LMICs (developing countries). Increased mortality associated with coagulopathy complications was of a greater magnitude among patients in LMICs. Additional research is needed regarding timely diagnosis of and intervention for coagulation derangements associated with COVID-19, particularly for limited-resource settings
The value of open-source clinical science in pandemic response: lessons from ISARIC
- Author
- Aasiyah Rashan
- Aasmine Kaur
- Abdulrahman Al-Fares
- Abhijit Duggal
- Adam Betz
- Adam Hall
- Adam Nowinski
- Adrian Ceccato
- Adrian Streinu-Cercel
- Adrian Tey
- Adrien Auvet
- Adrien Lemaignen
- Adrienne Chan
- Agamemnon Bakakos
- Agn??s Meybeck
- Agn??s Sommet
- Agnieszka Oldakowska
- Agostinho Monteiro
- Ahmad Afiq Ramli
- Ahmad Kashfi Haji Ab Rahman
- Ahmed Farooq
- Aidan Burrell
- Ailbhe Cullen
- Ailbhe Hayes
- Aine McCarthy
- Aine McElroy
- Aisha Kalsoom Mufti
- Aisling Gavin
- Aisling Murphy
- Aisling Murphy
- Akram Zaaqoq
- Al-Awwab Dabaliz
- Alan Hartman
- Alasdair Nazerali-Maitland
- Albert Groenendijk
- Alberto Cucino
- Alberto Sotto
- Alberto Uribe
- Alberto Zanella
- Albertus Beishuizen
- Aldo Rafael
- Aldric Manuel
- Alejandro Martin-Quiros
- Aleksander Rygh Holten
- Aleksandr Beljantsev
- Alessandra Martinelli
- Alessandra Notari
- Alex Browne
- Alex Nagrebetsky
- Alexa Debard
- Alexander Daniel Cornet
- Alexander J. Mentzer
- Alexander King
- Alexander Zoufaly
- Alexandra Bedossa
- Alexandra Coelho
- Alexandra Sperry
- Alexandre Ducancelle
- Alexandre Gaymard
- Alexandre Hoctin
- Alexandros Cavayas
- Ali Abbas
- Ali Ait Hssain
- Ali Hachemi
- Ali Liaquat
- Ali Raza
- Ali Rehan
- Alice Bogaarts
- Alicia Gonzalez
- Alif Adlan Mohd Thabit
- Alina Kalicinska
- Alison M. Meynert
- Alistair Nichol
- Allison McGeer
- Alpha Diallo
- Alphonsine Diouf
- AM Udara Lakshan Attanyake
- Am??lie Valran
- Amanda Corley
- Amanda Palacios
- Amanda Rojek
- Amandine Gagneux-Brunon
- Amar Bhatt
- Ami Stuart
- Amina Meziane
- Amirul Asyraf
- Amna Faheem
- Amy Lester-Grant
- Amy Stone
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- Anant Kataria
- Anatoliy Gavrylov
- Anca Streinu-Cercel
- Anders Benjamin Kildal
- Anders Tveita
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- Andr?? Roberto
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- Andra-Maris Post
- Andre Real
- Andrea Angheben
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- Andrea Kelly
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- Andreas Lind
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- Andrey A Svistunov
- Andriy Bal
- Andy Dong
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- Aneela Altaf
- Angel Asensio
- Angel Sanchez-Miralles
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- H M Upulee Pabasara
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- Rita Hinchion
- Ritika Ranjan
- Rob Klont
- Robert A. Fowler
- Roberta Cavalin
- Roberto Andini
- Roberto Roncon-Albuquerque Jr
- Robin Kobbe
- Rodrigo Diaz
- Rog??rio Silva
- Rolando Claure Del Granado
- Romain Basmaci
- Romain Decours
- Romain Guery
- Roman Ullrich
- Romans Matulevics
- Rosanna De Rosa
- Rosario Maria Torres Santos-Olmo
- Ross Hendry
- Rostane Gaci
- Roxane Courtois
- Rozanah Abd Rahman
- Rui Gomes
- Rui Pereira
- Rumaisah Satyawati
- Ruth Jimbo-Sotomayor
- Ruth Lyons
- Ruth N. Jorge Garc??a
- Ryadh Pokeerbux
- Ryan Kennedy
- Ryan Khoo
- Ryan S. Thwaites
- Ryuzo Abe
- S??bastien Preau
- S??lvia Ferreira
- S??rgio Gai??o
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- Saad Nseir
- Sabelline Bouchez
- Sabin Koirala
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- Saeeda Haider
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- Samuel McElwee
- Sandrine Couffin-Cadiergues
- Sanjay Lakhey
- Sanne Wesselius
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- Sarah Isgett
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- Sarah Redl
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- Scott Pharand
- Se??n Keating
- Seamus Daly
- Sean Donohue
- Sebastian Vencken
- Sebastiano Maria Colombo
- Segol??ne Greffe
- Senthilkumar Alegesan
- Sergio Poli
- Shahdattul Mawarni Taib
- Shaikh Sharjeel
- Shakeel Ahmed
- Shaminee Veeran
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- Shaun Thompson
- Shaunagh Browne
- Sheeba Hakak
- Sheharyar Ashraf
- Sheila C??rcel
- Sherry McDermott
- Sheryl Ann Abdukahil
- Shingo Adachi
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- Shiranee Sriskandan
- Shirin Tabrizi
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- Shoban Raj Vasudayan
- Shona C. Moore
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- Silvia Lourenco
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- Sobia Masood
- Sof??a Contreras
- Sofia Cardoso
- Sofia Prapa
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- Sophie Mahy
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- Sravya Pudota
- Sree Satyapriya
- Srinivas Murthy
- St??phane Jaureguiberry
- St??phane Lasry
- St??phane Sallaberry
- St??phanie Cousse
- St??phanie Fry
- Stanislas Rebaudet
- Steffi Ryckaert
- Stella Rousset
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- Stephanie Nonas
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- Stephanie-Susanne Stecher
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- Stephen Knight
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- Stuart Houltham
- Su Hwan Lee
- Subbarao Elapavaluru
- Subhash Acharya
- Sudhir Krishnan
- Sue Smith
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- Takayuki Ogura
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- Tarek Elshazly
- Tatiana Fonseca
- Tatsuya Kawasaki
- Tawnya Ogston
- Teck Fung Wong
- Teresa Lawrence
- Terese Hammond
- Tessa Broadley
- Th??o Treoux
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- Tharmini Ravi
- Tharwat Aisa
- Thavamany Kaleesvran
- Thibault Chiarabini
- Thierry Carmoi
- Thierry Mazzoni
- Thomas Flament
- Thomas Guimard
- Thomas Maitre
- Thomas Perpoint
- Thomas Staudinger
- Thushan de Silva
- Tiago Isidoro
- Tiago Reyes
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- Timo Brandenburger
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- Tiphaine Goulenok
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- Tom Solomon
- Tomoyuki Endo
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- Tony Trapani
- Toshiki Yokoyama
- Triona Downer
- Tristan Gigante
- Trude Steinsvik
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- V??ctor Quir??s Gonz??lez
- V??ronique Lemee
- Vadim Tieroshyn
- Val??rie Gaborieau
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- Valentine Campana
- Valeria Balan
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- Vanessa Sancho-Shimizu
- Vanessa Teotonio
- Vanina Meysonnier
- Vegard Skogen
- Ventzislava Petrov-Sanchez
- Vicente Souza-Dantas
- Victor Fomin
- Victoria Manda
- Victoria McEneany
- Victoria Shaw
- Vieri Parrini
- Vilmaris Quinones-Cardona
- Vincent Dinot
- Vincent Dubee
- Vincent Enouf
- Vincent Langlois
- Vincent Le Moing
- Vincent Peigne
- Vincent Pestre
- Vincent Thibault
- Vinothini Krishnan
- Virginie Williams
- Vladislav Mihnovit
- Volkan Korten
- Waasila Jassat
- Wai Ching Sin
- Walter Picard
- Wan Fadzlina Wan Muhd Shukeri
- Wei Han Hoh
- Wei Shen Lim
- Wendy S. Barclay
- William A. Paxton
- William Dechert
- William Greenhalf
- Wilna Oosthuyzen
- Wim Dieperink
- Xavier Duval
- Xavier S??nchez Choez
- Xin Ci Wong
- Yael Dishon
- Yan Chyi Tan
- Yaseen Arabi
- Yasmin Gani
- Yazdan Yazdanpanah
- Yen Tsen Saw
- Yew Sing Wong
- Yi Bin Ho
- Yi Lin Lee
- Yih-Sharng Chen
- Ymkje Stienstra
- Yoan Lavie-Badie
- Yoann Donohue
- Yock Ping Chow
- Younes Ait Tamlihat
- Younes Kerroumi
- Yun Sii Ing
- Yuri Kida
- Yusing Gu
- Yvelynne Kelly
- Yves Levy
- Zhang Duan Tham
- Zubair Umer
- Zul Amali Che Kamaruddin
- Zul Fakar
- Zulfiqar Sandhu
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
No full textInternational audienc
The value of open-source clinical science in pandemic response: lessons from ISARIC
- Author
- Abbas Ali
- Abdukahil Sheryl Ann
- Abdulkadir Nurul Najmee
- Abe Ryuzo
- Abel Laurent
- Absil Lara
- Acharya Subhash
- Acker Andrew
- Adachi Shingo
- Adam Elisabeth
- Adrião Diana
- Ageel Saleh Al
- Ahmed Shakeel
- Ain Quratul
- Ainscough Kate
- Aisa Tharwat
- Ait Hssain Ali
- Ait Tamlihat Younes
- Akimoto Takako
- Akmal Ernita
- Al Qasim Eman
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alam Tanvir
- Alegesan Senthilkumar
- Alegre Cynthia
- Alessi Marta
- Alex Beatrice
- Alexandre K. vin
- Alfoudri Huda
- Ali Shah Naseem
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Altaf Aneela
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Amira Nur
- Ammerlaan Heidi
- Ampaw Phoebe
- Andini Roberto
- Andrejak Claire
- Angheben Andrea
- Angoulvant François
- Ansart S. verine
- Anthonidass Sivanesen
- Antonelli Massimo
- Antunes de Brito Carlos Alexandre
- Anwar Kazi Rubayet
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Arali Rajeshwari
- Arancibia Francisco
- Araujo Carolline
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- Archambault Patrick
- Arenz Lukas
- Arlet Jean-Benoît
- Arnold-Day Christel
- Aroca Ana
- Arora Lovkesh
- Arora Rakesh
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- Asaki Motohiro
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- Tawfik Hassan
- Tedder Richard S.
- Tee Tze Yuan
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- Thompson Shaun
- Thomson David
- Thomson Emma C.
- Thurai Surain Raaj Thanga
- Thuy Duong Bich
- Thwaites Ryan S.
- Tierney Paul
- Tieroshyn Vadim
- Timashev Peter S.
- Timsit Jean-François
- Tirupakuzhi Vijayaraghavan Bharath Kumar
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- Trouillon Tiffany
- Truong Jeanne
- Tual Christelle
- Tubiana Sarah
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- Turmel Jean-Marie
- Turtle Lance C. W.
- Tveita Anders
- Twardowski Pawel
- Téoulé François
- Uchiyama Makoto
- Udayanga P. G. Ishara
- Udy Andrew
- Ullrich Roman
- Umer Zubair
- Uribe Alberto
- Usman Asad
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- van de Velde Stijn
- van den Berge Marcel
- van der Feltz Machteld
- van der Valk Paul
- van der Vekens Nicky
- van der Voort Peter
- van der Werf Sylvie
- van Dyk Marlice
- van Gulik Laura
- van Hattem Jarne
- van Lelyveld Steven
- van Netten Carolien
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- van Veen Ilonka
- Vanel Noémie
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- Vijayan Deepak
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- Vuotto Fanny
- Wahab Noor Hidayu
- Wahab Suhaila Abdul
- Wahid Nadirah Abdul
- Wainstein Marina
- Wan Muhd Shukeri Wan Fadzlina
- Wang Chih-Hsien
- Webb Steven Anthony
- Wei Jia
- Weil Katharina
- Wen Tan Pei
- Wesselius Sanne
- West T. Eoin
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Suzette
- Williams Virginie
- Wils Evert-Jan
- Wing Yiu Ng
- Wong Calvin
- Wong Teck Fung
- Wong Xin Ci
- Wong Yew Sing
- Xian Gan Ee
- Xian Lim Saio
- Xuan Kuan Pei
- Xynogalas Ioannis
- Yacoub Sophie
- Yakop Siti Rohani Binti Mohd
- Yamazaki Masaki
- Yazdanpanah Yazdan
- Yee Liang Hing Nicholas
- Yelnik C. cile
- Yeoh Chian Hui
- Yerkovich Stephanie
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Yuliarto Saptadi
- Zaaqoq Akram
- Zabbe Marion
- Zacharowski Kai
- Zahid Masliza
- Zahran Maram
- Zaidan Nor Zaila Binti
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zawadka Konrad
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/12/2021
- Field of study
No full textThrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry
- Author
- Abdukahil Sheryl Ann
- Abdulkadir Nurul Najmee
- Abe Ryuzo
- Abel Laurent
- Abrous Amal
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- Ahmed Shakeel
- Ainscough Kate
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- Alexandre Kévin
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- Bachelet Delphine
- Badr Claudine
- Baig Nadia
- Baillie J Kenneth
- Bak Erica
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- Balakrishnan Mohanaprasanth
- Balan Valeria
- Balazote Pablo Serrano
- Bani-Sadr Firouzé
- Barbalho Renata
- Barbosa Nicholas Yuri
- Barclay Wendy S
- Barnett Saef Umar
- Barnikel Michaela
- Barrasa Helena
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- Bartoli Marie
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- Boxma Bianca
- Boyer-Besseyre Marielle
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- Bozza Fernando Augusto
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- Burrell Aidan
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- Citarella Barbara Wanjiru
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- Combs Pamela
- Connolly Jennifer
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- da Silva Filipe Ana
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- Dankwa Emmanuelle A
- Dantas Jorge
- de Brito Carlos Alexandre Antunes
- de Castro Maisa Guimarães
- de Jong Menno
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- de Loughry Gillian
- De Montmollin Etienne
- de Oliveira França Rafael Freitas
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- Defous Eve
- Delacroix Isabelle
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- Delfos Nathalie M
- Deligiannis Ionna
- Dell'Amore Andrea
- Delmas Christelle
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- Diop Fara
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- Dishon Yael
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- Docherty Annemarie B
- Doherty Helen
- Donnelly Christl A
- Donnelly Maria
- Donohue Chloe
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- Dussol Bertrand
- Duthoit Juliette
- Duval Xavier
- Dyrhol-Riise Anne Margarita
- Ean Sim Choon
- Echeverria-Villalobos Marco
- Eddington Devin P
- Egan Siobhan
- Eira Carla
- Ekow Harrison Samuel Bernard
- El Sanharawi Mohammed
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- Everding Anna Greti
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- Fabre Isabelle
- Fabre Marc
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- Fahy Arabella
- Fairfield Cameron J
- Fanning Jonathon P
- Faria Pedro
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- Foley Jean
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- Forsyth Simon
- Foster Denise
- Foti Giuseppe
- Fourn Erwan
- Fowler Robert A
- Fraher Marianne
- Franch-Llasat Diego
- Fraser Christophe
- Fraser John
- Fraser John F
- Freire Marcela Vieira
- Fritz Ricardo
- Fry Stéphanie
- Fuentes Nora
- Fukuda Masahiro
- Gaborieau Valérie
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- Grable Margarite
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- Grandin Edward Wilson
- Granerud Beathe Kiland
- Granier Pascal
- Grasselli Giacomo
- Green Christopher A
- Greene Courtney
- Greenhalf William
- Greffe Segolène
- Grieco Domenico Luca
- Griffee Matthew
- Griffee Matthew J
- Griffiths Fiona
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- Groenendijk Albert
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- Gu Yusing
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- Hammond Terese
- Han Lim Yuen
- Haniffa Rashan
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- Hardwick Hayley
- Harrison Ewen M
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- Heerman Jan
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- Hoshino Koji
- Houas Ikram
- Hough Catherine L
- Houltham Stuart
- Hssain Ali Ait
- Hulot Jean-Sébastien
- Humaid Felwa Bin
- Hurd Abby
- Ijaz Samreen
- Ikram M Arfan
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- Jego Florence
- Jelani Anilawati Mat
- Jenum Synne
- Jimbo-Sotomayor Ruth
- Jiménez Miguel Pedrera
- Joe Ong Yiaw
- Jorge García Ruth N
- Joseph Cédric
- Joseph Mark
- Jourdain Mercé
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- Jung Anna
- Jung Hanna
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- Kafif Ouifiya
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- Keshav Sharma
- Khalid Imrana
- Khalil Antoine
- Khan Coralie
- Khan Irfan
- Kho Michelle E
- Khoo Denisa
- Khoo Ryan
- Khoo Saye
- Kiat Khor How
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- Kiiza Peter
- Kildal Anders Benjamin
- Kimmoun Antoine
- Kindgen-Milles Detlef
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- Kitamura Nobuya
- Klenerman Paul
- Klont Rob
- Knight Stephen R
- Komatsu Mamoru
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- Kpangon Arsène
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- Kyriakoulis Konstantinos
- L'Her Erwan
- Lachatre Marie
- Lacoste Marie
- Laffey John G
- Lafhej Nadhem
- Lagrange Marie
- Laine Fabrice
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- Lalueza Antonio
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- Langlois Vincent
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- Le Bihan Clément
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- Leathlobhair Niamh Ni
- Lee Low Lee
- Lee Biing Horng
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- Lee Yi Lin
- Leeming Gary
- Lefebvre Bénédicte
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- LeGac Sylvie
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- Lim Heng Benedict Sim
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- Liu Keibun
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- Loon Leong Chee
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- Lopez-Colon Dalia
- Loschner Anthony L
- Loubet Paul
- Loufti Bouchra
- Louis Guillame
- Lourenco Silvia
- Lowik Marije
- Loy Jia Shyi
- Lucet Jean-Christophe
- Luna Carlos M
- Lungu Olguta
- Luong Liem
- Luque Nestor
- Luton Dominique
- Lwin Nilar
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- Maasikas Olavi
- Mabiala Oryane
- Machado Moïse
- Machado Sara
- Macheda Gabriel
- Madiha Hashmi
- Mahieu Rafael
- Mahy Sophie
- Maia Ana Raquel
- Maier Lars S
- Maillet Mylène
- Maitre Thomas
- Malfertheiner Maximilian
- Malik Nadia
- Mallon Paddy
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- Malvy Denis
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- Mandelbrot Laurent
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- Markowicz Samuel
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- Martin-Blondel Guillaume
- Martin-Loeches Ignacio
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- Martinot Martin
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- McConnochie Rachael
- McDermott Sherry
- McDonald Sarah E
- McElroy Aine
- McElwee Samuel
- McEneany Victoria
- McEvoy Natalie
- McGeer Allison
- McKay Chris
- McKeown Johnny
- McLean Kenneth A
- McNally Paul
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- McPartlan Elaine
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- Mechlin Maggie
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- Mentzer Alexander J
- Mercier Emmanuelle
- Mercier Noémie
- Merckx Antoine
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- Merson Laura
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- Moore Sarah
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- Oh Tak-Hyuk
- Ohshimo Shinichiro
- Oliveira João
- Oliveira Larissa
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- Ong David SY
- Ong Jee Yan
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- Tveita Anders
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- Téoulé François
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- Usman Asad
- Uva Maria Sousa
- Uyeki Timothy M
- Vajdovics Cristinava
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- Valran Amélie
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- van den Berge Marcel
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- Villoldo Andrea
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- Visser Hannah
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- Vonkeman Harald
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- Wahab Noor Hidayu
- Wahab Suhaila Abdul
- Wahid Nadirah Abdul
- Wainstein Marina
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- Wang Chih-Hsien
- Webb Steve
- Wei Jia
- Weil Katharina
- Wen Tan Pei
- Wesselius Sanne
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Sue
- Williams Bailey
- Williams Patricia J
- Williams Virginie
- Wils Evert-Jan
- Wittman Jessica
- Wong Calvin
- Wong Teck Fung
- Wong Xin Ci
- Wong Yew Sing
- Xian Gan Ee
- Xian Lim Saio
- Xynogalas Ioannis
- Yamazaki Masaki
- Yang Toh Jordan Zhien
- Yarad Elizabeth
- Yazdanpanah Yazdan
- Yelnik Cécile
- Yeoh Chian Hui
- Yerkovich Stephanie
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Zaaqoq Akram
- Zabbe Marion
- Zacharowski Kai
- Zahid Masliza
- Zahran Maram
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- Elsevier BV
- Publication date
- 30/06/2023
- Field of study
No full textBackground: COVID-19 has been associated with a broad range of thromboembolic, ischemic, and hemorrhagic complications (coagulopathy complications). Most studies have focused on patients with severe disease from high-income countries (HICs). Objectives: The main aims were to compare the frequency of coagulopathy complications in developing countries (low- and middle-income countries [LMICs]) with those in HICs, delineate the frequency across a range of treatment levels, and determine associations with in-hospital mortality. Methods: Adult patients enrolled in an observational, multinational registry, the International Severe Acute Respiratory and Emerging Infections COVID-19 study, between January 1, 2020, and September 15, 2021, met inclusion criteria, including admission to a hospital for laboratory-confirmed, acute COVID-19 and data on complications and survival. The advanced-treatment cohort received care, such as admission to the intensive care unit, mechanical ventilation, or inotropes or vasopressors; the basic-treatment cohort did not receive any of these interventions. Results: The study population included 495,682 patients from 52 countries, with 63% from LMICs and 85% in the basic treatment cohort. The frequency of coagulopathy complications was higher in HICs (0.76%-3.4%) than in LMICs (0.09%-1.22%). Complications were more frequent in the advanced-treatment cohort than in the basic-treatment cohort. Coagulopathy complications were associated with increased in-hospital mortality (odds ratio, 1.58; 95% CI, 1.52-1.64). The increased mortality associated with these complications was higher in LMICs (58.5%) than in HICs (35.4%). After controlling for coagulopathy complications, treatment intensity, and multiple other factors, the mortality was higher among patients in LMICs than among patients in HICs (odds ratio, 1.45; 95% CI, 1.39-1.51). Conclusion: In a large, international registry of patients hospitalized for COVID-19, coagulopathy complications were more frequent in HICs than in LMICs (developing countries). Increased mortality associated with coagulopathy complications was of a greater magnitude among patients in LMICs. Additional research is needed regarding timely diagnosis of and intervention for coagulation derangements associated with COVID-19, particularly for limited-resource settings
Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19
- Author
- A M Udara Lakshan Attanyake
- Aasiyah Rashan
- Aasmine Kaur
- Abby Hurd
- Abdulrahman Al-Fares
- Abhijit Duggal
- Abid Khatak
- Adam Ali
- Adam Hall
- Adam Nowinski
- Adrian Ceccato
- Adrian Streinu-Cercel
- Adrian Tey
- Adrien Auvet
- Adrien Lemaignen
- Adrienne Chan
- Aftab Imtiaz
- Agamemnon Bakakos
- Agnieszka Oldakowska
- Agnès Meybeck
- Agnès Sommet
- Agostinho Monteiro
- Ahmad Afiq Ramli
- Ahmad Kashfi Haji Ab Rahman
- Ahmed Farooq
- Ailbhe Cullen
- Ailbhe Hayes
- Aine McCarthy
- Aine McElroy
- Aisha Kalsoom Mufti
- Aisling Gavin
- Aisling Murphy
- Aisling Murphy
- Akram Zaaqoq
- Al-Awwab Dabaliz
- Alan Hartman
- Alasdair Nazerali-Maitland
- Albert Groenendijk
- Alberto Sotto
- Alberto Uribe
- Alberto Zanella
- Albertus Beishuizen
- Aldo Rafael
- Aldric Manuel
- Alejandro Martin-Quiros
- Aleksander Rygh Holten
- Aleksandr Beljantsev
- Alessandra Notari
- Alex Browne
- Alex Nagrebetsky
- Alexa Debard
- Alexander Daniel Cornet
- Alexander J Mentzer
- Alexander King
- Alexander Zoufaly
- Alexandra Bedossa
- Alexandra Coelho
- Alexandra Sperry
- Alexandre Ducancelle
- Alexandre Gaymard
- Alexandre Hoctin
- Alexandros Cavayas
- Ali Ait Hssain
- Ali Hachemi
- Ali Liaquat
- Ali Raza
- Alice Bogaarts
- Alicia Gonzalez
- Alif Adlan Mohd Thabit
- Alina Kalicinska
- Alison M Meynert
- Allegra Chatterjee
- Allison McGeer
- Alpha Diallo
- Alphonsine Diouf
- Amanda Corley
- Amanda Palacios
- Amandine Gagneux-Brunon
- Amar Bhatt
- Ami Stuart
- Amin Khawaja
- Amina Meziane
- Amirul Asyraf
- Amna Faheem
- Amy Hackmann
- Amy Lester-Grant
- Amy Stone
- Amélie Valran
- Ana Catarino
- Ana Chora Sousa
- Ana da Silva Filipe
- Ana Freitas Ribeiro
- Ana Isabel de Pinho Oliveira
- Ana L Rios
- Ana Marques
- Ana Martins
- Ana Motos
- Ana Raquel Maia
- Anand Thakur
- Anant Kataria
- Anatoliy Gavrylov
- Anders Benjamin Kildal
- Anders Tveita
- Andra-Maris Post
- Andre Real
- Andrea Angheben
- Andrea Cortegiani
- Andrea Dell'Amore
- Andrea Kelly
- Andrea Rossanese
- Andrea Villoldo
- Andreas Lind
- Andrew Acker
- Andrew Hershey
- Andrew Udy
- Andrey Svistunov
- Andriy Bal
- André Cabie
- André Dias
- André Roberto
- Andy Dong
- Andy Law
- Aneela Altaf
- Angel Asensio
- Angel Sanchez-Miralles
- Angela Alberti
- Anika Atique
- Anilawati Mat Jelani
- Anissa Chair
- Anja Grosse Lordemann
- Anjellica Chen
- Ankana Satya
- Anna Beltrame
- Anna Ciullo
- Anna Greti Everding
- Anna Jung
- Anne Conrad
- Anne Guillaumot
- Anne Margarita Dyrhol-Riise
- Anne McCarthy
- Anne Opavsky
- Anne-Hélène Boivin
- Anne-Marie Guerguerian
- Anne-Sophie Boureau
- Anne-Sophie Resseguier
- Annelies Verbon
- Annemarie B Docherty
- Annmarie O Callaghan
- Annmarie O'Callaghan
- Ansley Hamer
- Anthony L Loschner
- Anthony Lemeur
- Anthony Nghi
- Antoine Cheret
- Antoine Khalil
- Antoine Kimmoun
- Antoine Merckx
- Anton Prinssen
- Antoni Torres
- Antonia Ricchiuto
- Antonio Arcadipane
- Antonio Lalueza
- Antonio Loforte
- Antonio Pesenti
- António Mesquita
- Anuraj Shankar
- Aoife Driscoll
- Aoife Kelly
- Aquiles Henriquez-Trujillo
- Arabella Fahy
- Ardiyan Apriyana
- Arianne Joy Corpuz
- Arie Zainul Fatoni
- Arjen M Dondorp
- Arnaud Scherpereel
- Arsalan Rahutullah
- Arshad Taqi
- Arsène Kpangon
- Arthur Garan
- Ary Serpa Neto
- Asad Usman
- Asfia Sultana
- Asgar Rishu
- Ashraf Sheharyar
- Asim Rana
- Asma Moin
- Astarini Hidayah
- Atif Siddiqui
- Attaur Rehman
- Audrey Barrelet
- Aurelius Bonfasius
- Aurore Bousquet
- Aurélie Papadopoulos
- Aurélie Veislinger
- Aurélie Wiedemann
- Axelle Braconnier
- Ayodhia Pitaloka
- Azlan Mat Soom
- B P Sanka Ruwan Sri Darshana
- Bailey Cassandra
- Baillie J Kenneth
- Bairbre McNicholas
- Bambang Pujo Semedi
- Barrio Noelia García
- Baruch Joaquín
- Basanta Gauli
- Basri Mat Nor
- Beane Abigail
- Beathe Kiland Granerud
- Beatrice Alex
- Beatriz Amorim Beltrão
- Benigno Ferreira
- Benjamin Bach
- Benjamin Lefevre
- Benjamin Smood
- Benjamine Sarton
- Benoit Visseaux
- Benoît Roze
- Benoît Thill
- Bernard Cholley
- Bernhard Roessler
- Bertrand Dussol
- Bianca Boxma
- Biing Horng Lee
- Birgitte Stiksrud
- Blake Mergler
- Blandine Rammaert
- Blumberg Lucille
- Bouchra Loufti
- Bozza Fernando
- Brenda Molloy
- Brenda Reeve
- Brendan Scicluna
- Brian Marsh
- Brigitte Elharrar
- Briseida Parra
- Broadley Tessa
- Bruno Levy
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- Bruno Pastene
- Bruno Sarmento Banheiro
- Bryan Whelan
- Budha Charan Singh
- Burrell Aidan
- Bénédicte Lefebvre
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- Caitriona Cody
- Calvin Wong
- Cameron J Fairfield
- Camile Bouisse
- Camille Couffignal
- Caren Friedrich
- Carine Roy
- Carla Eira
- Carlos Alexandre Antunes de Brito
- Carlos Lumbreras Bermejo
- Carlos M Luna
- Carlos Pimentel
- Carmen Infante Dominguez
- Carola Pierobon
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- Caroline Kosgei
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- Caroline Mudara
- Caroline Semaille
- Carolline Araujo
- Carrol Gamble
- Carson Gail
- Cassidy Codan
- Cassie Lawrence
- Catarina Pires
- Catarina Silva
- Catherine A Shaw
- Catherine Blier
- Catherine Chakveatze
- Catherine Chirouze
- Catherine L Hough
- Catherine Marquis
- Catherine Motherway
- Cecile Azoulay
- Cecilia Canepa
- Ceila Maria Sant Ana Malaque
- Celina Turchi Martelli
- Chamira Kodippily
- Chan Chee Eng
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- Charline Vauchy
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- Chih-Hsien Wang
- Chloe Donohue
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- Christel Arnold-Day
- Christelle Chantalat Auger
- Christelle Delmas
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- Christian Buesaquillo
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- Christian Rabaud
- Christophe Fraser
- Christophe Rapp
- Christopher A Green
- Christy Kay
- Ci Wong Xin
- Citarella Barbara Wanjiru
- Claire Andréjak
- Claire Foley
- Claire Kelly
- Claire Levy-Marchal
- Clara Flateau
- Clara Mouton Perrot
- Clare Jackson
- Clark D Russell
- Claudia Bianco
- Claudia Figueiredo-Mello
- Claudia Milena Orozco-Chamorro
- Claudia Montes
- Claudia Sepulveda
- Claudina Cruz
- Claudine Badr
- Claudio Duarte Fonseca
- Cleide Barrigoto
- Clotilde Allavena
- Clément Le Bihan
- Coilin Smyth
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- Coline Jaud-Fischer
- Colleen Curran
- Coralie Khan
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- Corinne Daniel
- Cornelius Rau
- Cosimo Cristella
- Courtney Greene
- Cristina De Rose
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- Cécile Goujard
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- Cédric Joseph
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- Céline Dorival
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- Céline Michelanglei
- César Vieira
- Dafsah Juzar
- Dag Henrik Reikvam
- Dagens Andrew
- Daisuke Kasugai
- Dalia Lopez-Colon
- Damien Bouhour
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- Danielle Jaafar
- Danilo Buonsenso
- Dankwa Emmanuelle A
- Darakhshan Kanwal
- Dario Sinatti
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- Diego Bastos Porto
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- Diego Franch-Llasat
- Dimitra Melia Myrodia
- Dinesh Kuriakose
- Diogo Borges
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- Diptesh Aryal
- Djura Piersma
- Domenico Luca Grieco
- Dominic So
- Dominique Deplanque
- Dominique Luton
- Donnelly Christl A
- Dori-Ann Martin
- Dorothea Rosenberger
- Dorothy Breen
- Dounia Bouhmani
- Douwe F Postma
- Drashti Patel
- Dubravka Supic
- Duc Nguyen
- Dunning Jake
- Dwi Utomo Nusantara
- Dzawani Muhamad
- Ebenezer Rabindrarajan
- Edel Meaney
- Eder Caceres
- Edmund Manning
- Edouard Soum
- Edward Wilson Grandin
- Efstathia Mihelis
- Eglantine Ferrand Devouge
- Egle Saviciute
- Eibhilin Higgins
- Eka Airlangga
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- Elias Iosifidis
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- Elisabetta Spinuzza
- Elise Artaud-Macari
- Ellen Shadowitz
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- Elotmani Loubna
- Elsa Nyamankolly
- Else Quist-Paulsen
- Ema Leal
- Eman Al Qasim
- Emanuele Durante-Mangoni
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- Emmanuel Roilides
- Emmanuelle Denis
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- Eric D'Ortenzio
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- Erni Nelwan
- Ernita Akmal
- Erwan Fourn
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- Escher Martina
- Esteban Garcia-Gallo
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- Sílvia Ferreira
- T Eoin West
- Taccone Fabio
- Tae Song
- Taha Pasha
- Tahira Jamal Mohamed
- Tak-Hyuk Oh
- Takako Akimoto
- Takayuki Ogura
- Taku Tanaka
- Tala Al-Dabbous
- Tamara Seitz
- Tan Pei Wen
- Tarek Elshazly
- Tatiana Fonseca
- Tawnya Ogston
- Teck Fung Wong
- Teresa Lawrence
- Terese Hammond
- Thalha Rashan
- Tharmini Ravi
- Tharwat Aisa
- Thavamany Kaleesvran
- Thibault Chiarabini
- Thierry Carmoi
- Thierry Mazzoni
- Thomas Flament
- Thomas Guimard
- Thomas Maitre
- Thomas Perpoint
- Thomas Staudinger
- Thushan de Silva
- Théo Treoux
- Tiago Isidoro
- Tiago Reyes
- Tiffany Trouillon
- Timo Brandenburger
- Timothy M Uyeki
- Ting Soo Chow
- Tiphaine Goulenok
- Tjard Schermer
- Todd C Lee
- Todd Karsies
- Tom Drake
- Tom Fletcher
- Tom Solomon
- Tomoyuki Endo
- Toni Duculan
- Tony Trapani
- Toshiki Yokoyama
- Triona Downer
- Tristan Gigante
- Trude Steinsvik
- Tze Vee Soh
- Tze Yuan Tee
- Tânia Sequeira
- Vadim Tieroshyn
- Valentine Campana
- Valeria Balan
- Valla Sahraei
- Valérie Gaborieau
- Valérie Garrait
- Valérie Gissot
- Vanessa Sancho-Shimizu
- Vanessa Teotonio
- Vanina Meysonnier
- Vecham Pavan Kumar
- Vegard Skogen
- Ventzislava Petrov-Sanchez
- Vicente Souza-Dantas
- Victor Fomin
- Victoria Janes
- Victoria Manda
- Victoria McEneany
- Victoria Shaw
- Vilmaris Quinones-Cardona
- Vincent Dinot
- Vincent Dubee
- Vincent Enouf
- Vincent Langlois
- Vincent Le Moing
- Vincent Peigne
- Vincent Pestre
- Vincent Thibault
- Vinothini Krishnan
- Virginie Williams
- Vladislav Mihnovit
- Véronique Lemee
- Víctor Quirós González
- Wai Ching Sin
- Walter Picard
- Wan Fadzlina Wan Muhd Shukeri
- Wei Han Hoh
- Wei Shen Lim
- Wei Jia
- Wendy S Barclay
- William A Paxton
- William Dechert
- William Finlayson
- William Greenhalf
- Wilna Oosthuyzen
- Wils Evert-Jan
- Wim Dieperink
- Wing Yiu Ng
- Xavier Duval
- Yael Dishon
- Yan Chyi Tan
- Yaseen Arabi
- Yasmin Gani
- Yazdan Yazdanpanah
- Yen Tsen Saw
- Yew Sing Wong
- Yi Bin Ho
- Yi Lin Lee
- Yih-Sharng Chen
- Ymkje Stienstra
- Yoan Lavie-Badie
- Yoann Donohue
- Yock Ping Chow
- Younes Ait Tamlihat
- Younes Kerroumi
- Yun Sii Ing
- Yuri Kida
- Yusing Gu
- Yvelynne Kelly
- Yves Levy
- Zhang Duan Tham
- Zul Amali Che Kamaruddin
- Zul Fakar
- Zulfiqar Sandhu
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 28/02/2023
- Field of study
Get PDFBackground: We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) COVID-19 cohort, one of the world's largest international, standardized data sets concerning hospitalized patients. Methods: The data set analysed includes COVID-19 patients hospitalized between January 2020 and January 2022 in 52 countries. We investigated how symptoms on admission, co-morbidities, risk factors and treatments varied by age, sex and other characteristics. We used Cox regression models to investigate associations between demographics, symptoms, co-morbidities and other factors with risk of death, admission to an intensive care unit (ICU) and invasive mechanical ventilation (IMV). Results: Data were available for 689 572 patients with laboratory-confirmed (91.1%) or clinically diagnosed (8.9%) SARS-CoV-2 infection from 52 countries. Age [adjusted hazard ratio per 10 years 1.49 (95% CI 1.48, 1.49)] and male sex [1.23 (1.21, 1.24)] were associated with a higher risk of death. Rates of admission to an ICU and use of IMV increased with age up to age 60 years then dropped. Symptoms, co-morbidities and treatments varied by age and had varied associations with clinical outcomes. The case-fatality ratio varied by country partly due to differences in the clinical characteristics of recruited patients and was on average 21.5%. Conclusions: Age was the strongest determinant of risk of death, with a ∼30-fold difference between the oldest and youngest groups; each of the co-morbidities included was associated with up to an almost 2-fold increase in risk. Smoking and obesity were also associated with a higher risk of death. The size of our international database and the standardized data collection method make this study a comprehensive international description of COVID-19 clinical features. Our findings may inform strategies that involve prioritization of patients hospitalized with COVID-19 who have a higher risk of death
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19
- Author
- A M Udara Lakshan Attanyake
- Aasiyah Rashan
- Aasiyah Rashan 9
- Aasmine Kaur
- Abdulrahman Al-Fares
- Abhijit Duggal
- Abi Beane 10
- Abid Khatak
- Abigail Beane
- Adam Ali
- Adam Betz
- Adam Hall
- Adam Nowinski
- Adrian Ceccato
- Adrian Streinu-Cercel
- Adrian Tey
- Adrien Auvet
- Adrien Lemaignen
- Adrienne Chan
- Aftab Imtiaz
- Agamemnon Bakakos
- Agnieszka Oldakowska
- Agnès Meybeck
- Agnès Sommet
- Agostinho Monteiro
- Ahmad Afiq Ramli
- Ahmad Kashfi Haji Ab Rahman
- Ahmed Farooq
- Aidan Burrell
- Ailbhe Cullen
- Ailbhe Hayes
- Aine McCarthy
- Aine McElroy
- Aisha Kalsoom Mufti
- Aisling Gavin
- Aisling Murphy
- Akram Zaaqoq
- Al-Awwab Dabaliz
- Alan Hartman
- Alasdair Nazerali-Maitland
- Albert Groenendijk
- Alberto Cucino
- Alberto Sotto
- Alberto Uribe
- Alberto Zanella
- Albertus Beishuizen
- Aldo Rafael
- Aldric Manuel
- Alejandro Martin-Quiros
- Aleksander Rygh Holten
- Aleksandr Beljantsev
- Alessandra Martinelli
- Alessandra Notari
- Alex Browne
- Alexa Debard
- Alexander Daniel Cornet
- Alexander J Mentzer
- Alexander King
- Alexander Zoufaly
- Alexandra Bedossa
- Alexandra Coelho
- Alexandra Sperry
- Alexandre Ducancelle
- Alexandre Gaymard
- Alexandre Hoctin
- Alexandros Cavayas
- Alfredo Antonio Chetta
- Ali Abbas
- Ali Ait Hssain
- Ali Hachemi
- Ali Liaquat
- Ali Raza
- Alice Bogaarts
- Alicia Gonzalez
- Alif Adlan Mohd Thabit
- Alina Kalicinska
- Alison M Meynert
- Alistair Nichol
- Allegra Chatterjee
- Allison McGeer
- Alpha Diallo
- Alphonsine Diouf
- Amanda Corley
- Amanda Palacios
- Amanda Rojek
- Amanda Rojek 5
- Amandine Gagneux-Brunon
- Amar Bhatt
- Ami Stuart
- Amiel A Dror
- Amin Khawaja
- Amina Meziane
- Amirul Asyraf
- Amna Faheem
- Amy Hackmann
- Amy Lester-Grant
- Amy Stone
- Amélie Valran
- Ana Aroca
- Ana Catarino
- Ana Chora Sousa
- Ana da Silva Filipe
- Ana Freitas Ribeiro
- Ana Isabel de Pinho Oliveira
- Ana L Rios
- Ana Luiza Valle
- Ana Marques
- Ana Martins
- Ana Motos
- Ana Raquel Maia
- Anais Rampello
- Anand Thakur
- Anant Kataria
- Anatoliy Gavrylov
- Anca Streinu-Cercel
- Anders Benjamin Kildal
- Anders Benteson Nygaard
- Anders Tveita
- Andra-Maris Post
- Andre Real
- Andrea Angheben
- Andrea Cortegiani
- Andrea Dell'Amore
- Andrea Dias
- Andrea Kelly
- Andrea Rossanese
- Andrea Ticinesi
- Andrea Villoldo
- Andreas Lind
- Andrew Acker
- Andrew Dagens
- Andrew Dagens 5
- Andrew Hershey
- Andrew Law
- Andrew Letizia
- Andrew Udy
- Andrey A Svistunov
- Andriy Bal
- André Cabie
- André Dias
- André Roberto
- Andrés Orquera
- Andy Dong
- Andy Law
- Aneela Altaf
- Angel Asensio
- Angel Sanchez-Miralles
- Angela Alberti
- Anika Atique
- Anilawati Mat Jelani
- Anissa Chair
- Anja Grosse Lordemann
- Anjellica Chen
- Ankana Satya
- Anna Beltrame
- Anna Ciullo
- Anna Greti Everding
- Anna Jung
- Anne Conrad
- Anne Guillaumot
- Anne Margarita Dyrhol-Riise
- Anne McCarthy
- Anne Opavsky
- Anne-Hélène Boivin
- Anne-Marie Guerguerian
- Anne-Sophie Boureau
- Anne-Sophie Resseguier
- Annelies Verbon
- Annemarie B Docherty
- Annmarie O Callaghan
- Annmarie O'Callaghan
- Ansley Hamer
- Anthony L Loschner
- Anthony Lemeur
- Anthony Nghi
- Antoine Cheret
- Antoine Khalil
- Antoine Kimmoun
- Antoine Merckx
- Anton Prinssen
- Antoni Torres
- Antonia Ho
- Antonia Ricchiuto
- Antonio Arcadipane
- Antonio Lalueza
- Antonio Loforte
- Antonio Pesenti
- António Mesquita
- Anuraj Shankar
- Aoife Driscoll
- Aoife Kelly
- Aquiles Henriquez-Trujillo
- Arabella Fahy
- Ardiyan Apriyana
- Arianne Joy Corpuz
- Arie Zainul Fatoni
- Arjen M Dondorp
- Arnaud Scherpereel
- Arne Søraas
- Arsalan Rahutullah
- Arshad Taqi
- Arsène Kpangon
- Arthur Garan
- Ary Serpa Neto
- Asad Usman
- Asami Ito
- Asfia Sultana
- Asgar Rishu
- Ashraf Sheharyar
- Asim Rana
- Asma Moin
- Astarini Hidayah
- Atif Siddiqui
- Attaur Rehman
- Audrey Barrelet
- Audrey Dubot-Pérès
- Aurelius Bonfasius
- Aurore Bousquet
- Aurélie Papadopoulos
- Aurélie Veislinger
- Aurélie Wiedemann
- Axelle Braconnier
- Ayodhia Pitaloka
- Azlan Mat Soom
- B P Sanka Ruwan Sri Darshana
- Bailey Cassandra
- Bairbre McNicholas
- Bambang Pujo Semedi
- Barbara Wanjiru Citarella
- Barbara Wanjiru Citarella 5
- Basanta Gauli
- Basri Mat Nor
- Bato Hammarström
- Beathe Kiland Granerud
- Beatrice Alex
- Beatriz Amorim Beltrão
- Ben Morton
- Benedict Sim Lim Heng
- Benigno Ferreira
- Benjamin Bach
- Benjamin Lefevre
- Benjamin Smood
- Benjamine Sarton
- Benoit Visseaux
- Benoît Roze
- Benoît Thill
- Bernard Cholley
- Bernardo Neves
- Bernhard Roessler
- Bertrand Dussol
- Bharath Kumar Tirupakuzhi Vijayaraghavan
- Bianca Boxma
- Bianca DeBenedictis
- Biing Horng Lee
- Birgitte Stiksrud
- Blake Mergler
- Blandine Rammaert
- Bouchra Loufti
- Bountoy Sibounheuang
- Brenda Molloy
- Brenda Reeve
- Brian Marsh
- Brigid Flynn
- Brigitte Elharrar
- Briseida Parra
- Bronner P Gonçalves
- Bronner P Gonçalves 5
- Bruno Levy
- Bruno Lina
- Bruno Pastene
- Bruno Sarmento Banheiro
- Bryan Whelan
- Budha Charan Singh
- Bénédicte Lefebvre
- Bénédicte Rossignol
- Caitriona Cody
- Calvin Wong
- Cameron J Fairfield
- Camile Bouisse
- Camilla Lund Søraas
- Camille Couffignal
- Caren Friedrich
- Carine Roy
- Carla Eira
- Carlo Ferrari
- Carlo Giaquinto
- Carlos Alexandre Antunes de Brito
- Carlos Lumbreras Bermejo
- Carlos M Luna
- Carlos Pimentel
- Carlotta Mutti
- Carmen Infante Dominguez
- Carola Pierobon
- Carolien van Netten
- Caroline Kosgei
- Caroline Martins Rego
- Caroline Mudara
- Caroline Semaille
- Carolline Araujo
- Carrol Gamble
- Cassidy Codan
- Cassie Lawrence
- Catarina Pires
- Catarina Silva
- Caterina Caminiti
- Catherine A Shaw
- Catherine Blier
- Catherine Chakveatze
- Catherine Chirouze
- Catherine L Hough
- Catherine Marquis
- Catherine Motherway
- Cecile Azoulay
- Cecilia Canepa
- Ceila Maria Sant'Ana Malaque
- Celina Turchi Martelli
- Chamira Kodippily
- Chan Chee Eng
- Chantre Lima
- Charbel Maroun Eid
- Charlene Da Silveira
- Charles Crepy D'Orleans
- Charline Vauchy
- Charlotte Salmon Gandonniere
- Charlotte Summers
- Cheryl Bartone
- Chian Hui Yeoh
- Chiara Robba
- Chiara Simona Cardellino
- Chiara Vitiello
- Chih-Hsien Wang
- Chloe Donohue
- Chris Kandel
- Chris McKay
- Christel Arnold-Day
- Christelle Chantalat Auger
- Christelle Delmas
- Christelle Paul
- Christelle Tual
- Christian Buesaquillo
- Christian Prebensen
- Christian Rabaud
- Christiana Kartsonaki
- Christiana Kartsonaki 5
- Christl A Donnelly
- Christophe Fraser
- Christophe Rapp
- Christopher A Green
- Christy Kay
- Claire Andrejak
- Claire Foley
- Claire Kelly
- Claire Levy-Marchal
- Claire Roger
- Clara Flateau
- Clara Mouton Perrot
- Clare Jackson
- Clarice Tanaka
- Clark D Russell
- Clark D Russell 8
- Clark Owyang
- Claudia Bianco
- Claudia Figueiredo-Mello
- Claudia Milena Orozco-Chamorro
- Claudia Montes
- Claudia Sepulveda
- Claudina Cruz
- Claudine Badr
- Claudio Duarte Fonseca
- Cleide Barrigoto
- Clotilde Allavena
- Clément Le Bihan
- Coca Necsoi
- Coilin Smyth
- Colin McArthur
- Colin McCloskey
- Coline Jaud-Fischer
- Colleen Curran
- Conar O'Neil
- Coralie Khan
- Coralie Tardivon
- Corine Delsing
- Corinne Daniel
- Cornelius Rau
- Courtney Greene
- Craig French
- Cristina De Rose
- Cristinava Vajdovics
- Cynthia Alegre
- Cynthia Braga
- Cyril Cadoz
- Cyril Le Bris
- Cécile Goujard
- Cécile Mear-Passard
- Cécile Tromeur
- Cécile Yelnik
- Cédric Joseph
- Cédric Laouénan
- Céline Dorival
- Céline Ficko
- Céline Michelanglei
- César Vieira
- Dafsah Juzar
- Dag Henrik Reikvam
- Daisuke Kasugai
- Dalia Lopez-Colon
- Damien Bouhour
- Dan Meyer
- Daniel Glikman
- Daniel Haber
- Daniel Herr
- Daniel Ivulich
- Daniel Marino
- Daniel Mathieu
- Daniel Munblit
- Daniel Perez
- Daniel Vidali Fryer 6
- Daniela Guerreiro
- Danielle Jaafar
- Danilo Buonsenso
- Danoy Chommanam
- Darakhshan Kanwal
- Dario Sinatti
- Darren Dahly
- Darshana Hewa Kandamby
- Dave Nagpal
- David Bellemare
- David Dean
- David L Robertson
- David Maslove
- David Molina
- David Richardson
- David S Y Ong
- David Stuart
- David Thomson
- David Zucman
- Davide Chiumello
- Dawn Higgins
- Debby Bogaert
- Decy Subekti
- Deepak Vijayan
- Deepali Kumar
- Deepashankari Suppiah
- Dehbia Benkerrou
- Deirdre Flynn
- Delphine Bachelet
- Delphine Bergeaud
- Delphine Lariviere
- Demetrios Kutsogiannis
- Denis Butnaru
- Denis Garot
- Denis Malvy
- Denisa Khoo
- Denise Battaglini
- Denise Foster
- Denise Jaworsky
- Denise Richardson
- Denisse Bazan Dow
- Derbrenn OConnor
- Desy Rusmawatiningtyas
- Detlef Kindgen-Milles
- Dewi Guellec
- Diana Adrião
- Diana Póvoas
- Diane Descamps
- Diane Ponscarme
- Didier Laureillard
- Diego Bastos Porto
- Diego de Mendoza
- Diego Fernando Bautista Rincon
- Diego Franch-Llasat
- Diego Rolando Morocho Tutillo
- Dimitra Melia Myrodia
- Dinesh Kuriakose
- Diogo Borges
- Diogo Lopes
- Diptesh Aryal
- Djura Piersma
- Domenico Luca Grieco
- Dominic So
- Dominique Deplanque
- Dominique Luton
- Dori-Ann Martin
- Dorothea Rosenberger
- Dorothy Breen
- Dounia Bouhmani
- Douwe F Postma
- Dr Rajesh Mohan Shetty
- Drashti Patel
- Dubravka Supic
- Duc Nguyen
- Duong Bich Thuy
- Dwi Utomo Nusantara
- Dyah Kanyawati
- Dzawani Muhamad
- Ebenezer Rabindrarajan
- Edel Meaney
- Eder Caceres
- Edmund Manning
- Edouard Soum
- Edward Wilson Grandin
- Edwin Fernando Paredes Oña
- Efstathia Mihelis
- Eglantine Ferrand Devouge
- Egle Saviciute
- Eibhilin Higgins
- Eka Airlangga
- Eka Yudha Lantang
- Elaine Conway
- Elaine Gilroy
- Elaine McPartlan
- Elena Gallego Curto
- Elena Molinos
- Elena Ranza
- Elias Iosifidis
- Elisa Demonchy
- Elisabeth Adam
- Elisabeth Botelho-Nevers
- Elisabetta Spinuzza
- Elise Artaud-Macari
- Elizabeth Ashley
- Ellen Shadowitz
- Elodie Curlier
- Elsa Nyamankolly
- Else Quist-Paulsen
- Ema Leal
- Eman Al Qasim
- Emanuele Durante-Mangoni
- Emily Martin
- Emily Neumann
- Emily Somers
- Emma C Thomson
- Emma Clarke
- Emma Costigan
- Emmanuel Roilides
- Emmanuelle A Dankwa
- Emmanuelle Denis
- Emmanuelle Mercier
- Enrico Adriano
- Eric D'Ortenzio
- Eric Delaveuve
- Eric Gnall
- Eric Oziol
- Eric Senneville
- Erica Bak
- Erlina Burhan
- Erni Nelwan
- Ernita Akmal
- Erwan Fourn
- Erwan L'Her
- Esteban Garcia-Gallo
- Esteban Garcia-Gallo 1
- Ethan Kurtzman
- Etienne De Montmollin
- Eva Geraud
- Eva Miranda Marwali
- Eva Stolz
- Eve Defous
- Evelyne Kestelyn
- Evert-Jan Wils
- Ewa Talarek
- Ewen M Harrison
- Eyrun Floerecke Kjetland Kjetland
- Eyvind W Axelsen
- Fabian Patauner
- Fabio Guarracino
- Fabio S Taccone
- Fabrice Laine
- Fakhir Haidri
- Fanny Vuotto
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- Farah Nadia Mohd-Hanafiah
- Farah Nadiah Bidin
- Federica Fogliazza
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- Ferruccio Mele
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- Filipa Sequeira
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- Fiona Griffiths
- Fionnuala O Brien
- Firouzé Bani-Sadr
- Florence Jego
- Florent Peelman
- Florentia Kaguelidou
- Flávio Marino
- France Mentré
- Francesca Carlacci
- Francesco Rausa
- Francisco Arancibia
- Frank Bloos
- Frank Manetta
- Frank Olav Pettersen
- François Angoulvant
- François Bissuel
- François Bompart
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- François Goehringer
- François Lamontagne
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- François Téoulé
- François-Xavier Catherine
- François-Xavier Ferrand
- François-Xavier Lescure
- Fredrik Müller
- Frédérick D'Aragon
- Félix Djossou
- G Argin
- Gabriel Macheda
- Gabriel Suen
- Gabriele Sales
- Gabrielle Ragazzo
- Gail Carson
- Galyna Kutsyna
- Gamage Dona Dilanthi Priyadarshani
- Gan Ee Xian
- Ganesh Kumar
- Gary Leeming
- Gary Schwartz
- Gayatri Vishwanathan
- Gayle Carney
- Gennaro Martucci
- Geoffrey Liegeon
- Georges Le Falher
- Georgios Pollakis
- Ger Curley
- Geraldine Goco
- Gerard Curley
- Gezy Giwangkancana
- Ghulam Rasheed
- Giacomo Grasselli
- Gianluigi Li Bassi
- Giles J Peek
- Gilles Peytavin
- Gillian de Loughry
- Giorgia Montrucchio
- Giorgio Economopoulos
- Giovanna Occhipinti
- Giovanna Panarello
- Giri Shan Rajahram
- Gitte Van Twillert
- Giulia Bertoli
- Giuliano Michelagnoli
- Giulio Giovanni Cavalli
- Giuseppe Foti
- Giuseppe Maglietta
- Gloria Crowl
- Graham S Cooke
- Grazielle Viana Ramos
- Gregory Purcell
- Gretchen Lemmink
- Gry Kloumann Bekken
- Grégory Corvaisier
- Gugapriyaa Muyandy
- Guillame Louis
- Guillaume Lingas
- Guillaume Martin-Blondel
- Guillermo Giordano
- Guillermo Maestro de la Calle
- Guylaine Castor-Alexandre
- Gwenaël Le Moal
- Gwenhaël Colin
- Gyan Sandhu
- Ha Sha Lene
- Haider Hirkani
- Haixia Shi
- Hajnal-Gabriela Illes
- Hanan Fateena
- Hanna Jung
- Hanna Renk
- Hannah Habraken
- Hannah Keane
- Hannah Visser
- Hans Martin Bosse
- Harald Vonkeman
- Harrison Kihuga
- Hashmi Madiha
- Hassan Tawfik
- Hayato Taniguchi
- Hayley Hardwick
- Hazel Bergin
- Heidi Ammerlaan
- Heidi Dalton
- Heidi Gruner
- Helen Doherty
- Helen Tuite
- Helena Barrasa
- Hem Paneru
- Heng Gee Lee
- Henk Vanoverschelde
- Henrique Mateus Fernandes
- Henry Castrillón
- Hernando Torres-Zevallos
- Hervé Le Nagard
- Hiba Abu Zayyad
- Hiba Zayyad
- Hikombo Hitoto
- Himasha Muvindi
- Himed Musaab
- Hiroaki Hiraiwa
- Hiroaki Shimizu
- Hiroyuki Tanaka
- Hiu Jian Chua
- Hodane Yonis
- Hoi Ping Shum
- Holger Neb
- Hon Shen Png
- Hongru Ren
- Hubert Tessier-Grenier
- Huda Alfoudri
- Huda Taqdees
- Hugo Inácio
- Hugo Miranda-Maldonado
- Hugo Mouquet
- Hugues Aumaitre
- Hugues Cordel
- Husna Begum
- Huynh Trung Trieu
- Hwa Jin Cho
- Hélène Esperou
- Hélène Salvator
- Iam Claire E Sarmiento
- Ida Carroll
- Ignacio Martin-Loeches
- Ikram Houas
- Ilaria Valzano
- Ilka Engelmann
- Ilonka van Veen
- Imran Ali
- Imrana Khalid
- Indrek Rätsep
- Ingrid G Bustos
- Inês Carqueja
- Ioana Grigoras
- Ioannis Trontzas
- Ioannis Xynogalas
- Ionna Deligiannis
- Iqbal Elyazar
- Iqbal Hussain
- Irene Aragao
- Irfan Khan
- Isabel Ferreira
- Isabela Saba
- Isabella Bianchi
- Isabelle Delacroix
- Isabelle Enderle
- Isabelle Fabre
- Isabelle Gorenne
- Isabelle Hoffmann
- Isabelle Michelet
- Isabelle Pironneau
- ISARIC Clinical Characterization Group
- Ithan D Peltan
- Ivo Castro
- J Kenneth Baillie
- J Kevin Baird
- Jack Song Chia
- Jacky Y Suen
- Jacob Magara
- Jacobien Ellerbroek
- Jade Ghosn
- Jae Burm Kim
- Jaganathan Selvanayagam
- Jai Madhok
- Jaime Cruz Rojo
- Jaime Hernandez-Montfort
- Jake Dunning
- Jake Dunning 5
- Jamel Ortoleva
- James Joshua Douglas
- James Lee
- James Lee 5
- James Scott-Brown
- James Vickers
- Jan Cato Holter
- Jan Heerman
- Jan-Erik Berdal
- Jananee Thirumanickam
- Jane Ngure
- Janet Harrison
- Janet Liang
- Janet T Scott
- Jaques Sztajnbok
- Jarne Van Hattem
- Jason Bouziotis
- Javier Maynar
- Javier Osatnik
- Jawad Hameed
- Jean Baptiste Assie
- Jean Christophe Lucet
- Jean Foley
- Jean-Benoît Arlet
- Jean-Charles Gagnard
- Jean-Charles Preiser
- Jean-Christophe Goffard
- Jean-Daniel Lelievre
- Jean-François Payen
- Jean-François Timsit
- Jean-Luc Diehl
- Jean-Marc Chapplain
- Jean-Marie Turmel
- Jean-Sébastien Hulot
- Jeanne Sibiude
- Jeanne Truong
- Jee Yan Ong
- Jeff Powis
- Jeffrey Aliudin
- Jeffrey Javidfar
- Jelmer Talsma
- Jennifer Clarke
- Jennifer June
- Jenny Lennon
- Jeronimo Graf
- Jess Gibson
- Jesse Gitaka
- Jia Shyi Loy
- Jia Wei
- Jia Wei 5
- Jillian Deacon
- Jimmy Ming-Yang Hsu
- Jimmy Mullaert
- Jin Yi Goh
- Jo Dalton
- Joan Gómez-Junyent
- Joana Ferrão
- Joanne Downey
- Joao Mendes
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- Joaquín Baruch
- Job van der Palen
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- Quratul Ain Khan
- Rachael McConnochie
- Rachael Parke
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- Rachida Ouissa
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- Raphaël Borie
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- Raquel Pinto
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- Sivanesen Anthonidass
- Smaragdi Kalomoiri
- Sobia Masood
- Sofia Cardoso
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- Soizic Le Mestre
- Sommay Keomany
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- Sravya Pudota
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- Srinivas Murthy
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- Stéphane Jaureguiberry
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- Stéphanie Cousse
- Stéphanie Fry
- Su Hwan Lee
- Subbarao Elapavaluru
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- Sue Smith
- Sue Smith 5
- Suhaila Abdul Wahab
- Sung-Min Cho
- Surain Raaj Thanga Thurai
- Suresh Kumar Chidambaram
- Surya Otto Wijaya
- Susana Cabral
- Susana Fernandes
- Susanne Dudman
- Sushil Khanal
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- Suwarti Suwarti
- Suzanne Bennett
- Suzette Willems
- Swosti Joshi
- Syamin Asyraf Shahidan
- Sybille Bevilcaqua
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- Sylvie Behilill
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- Synne Jenum
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- Tak-Hyuk Oh
- Takako Akimoto
- Takayuki Ogura
- Taku Tanaka
- Takuya Shiga
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- Tan Pei Wen
- Tarek Elshazly
- Tatiana Fonseca
- Tatsuya Kawasaki
- Tawnya Ogston
- Teck Fung Wong
- Teresa Lawrence
- Terese Hammond
- Thalha Rashan
- Tharmini Ravi
- Tharwat Aisa
- Thavamany Kaleesvran
- Thibault Chiarabini
- Thierry Carmoi
- Thierry Mazzoni
- Thipsavanh Bounphiengsy
- Thomas Flament
- Thomas Guimard
- Thomas Maitre
- Thomas Perpoint
- Thomas Staudinger
- Thushan de Silva
- Théo Treoux
- Tiago Isidoro
- Tiago Reyes
- Tiffany Trouillon
- Timo Brandenburger
- Timothy M Uyeki
- Ting Soo Chow
- Tiphaine Goulenok
- Tiziana Meschi
- Tjard Schermer
- Todd C Lee
- Todd Karsies
- Tom Drake
- Tom Fletcher
- Tom Solomon
- Tomoyuki Endo
- Toni Duculan
- Tony Trapani
- Toshiki Yokoyama
- Touxiong Yiaye
- Triona Downer
- Tristan Gigante
- Trude Steinsvik
- Tze Vee Soh
- Tze Yuan Tee
- Tânia Sequeira
- Vadim Tieroshyn
- Valentine Campana
- Valeria Balan
- Valeria Balan 5
- Valla Sahraei
- Valérie Gaborieau
- Valérie Garrait
- Valérie Gissot
- Vanessa Sancho-Shimizu
- Vanessa Teotonio
- Vanina Meysonnier
- Vegard Skogen
- Ventzislava Petrov-Sanchez
- Vicente Souza-Dantas
- Victor Fomin
- Victoria Manda
- Victoria McEneany
- Victoria Shaw
- Vieri Parrini
- Viladeth Praphasiri
- Vilmaris Quinones-Cardona
- Vincent Dinot
- Vincent Dubee
- Vincent Enouf
- Vincent Langlois
- Vincent Le Moing
- Vincent Peigne
- Vincent Pestre
- Vincent Thibault
- Vinothini Krishnan
- Virginie Williams
- Vladislav Mihnovit
- Volkan Korten
- Véronique Lemee
- Víctor Quirós González
- Waasila Jassat
- Wai Ching Sin
- Walter Picard
- Wan Fadzlina Wan Muhd Shukeri
- Wei Han Hoh
- Wei Shen Lim
- Wendy S Barclay
- William A Paxton
- William Dechert
- William Finlayson
- William Greenhalf
- Wilna Oosthuyzen
- Wim Dieperink
- Wing Yiu Ng
- Xavier Duval
- Xavier Sánchez Choez
- Xin Ci Wong
- Yael Dishon
- Yan Chyi Tan
- Yanay Gorelik
- Yaseen Arabi
- Yasmin Gani
- Yazdan Yazdanpanah
- Yen Tsen Saw
- Yew Sing Wong
- Yi Bin Ho
- Yi Lin Lee
- Yih-Sharng Chen
- Ymkje Stienstra
- Yoan Lavie-Badie
- Yoann Donohue
- Yock Ping Chow
- Younes Ait Tamlihat
- Younes Kerroumi
- Yuli V Fuentes 1
- Yun Sii Ing
- Yuri Kida
- Yusing Gu
- Yvelynne Kelly
- Yves Levy
- Zhang Duan Tham
- Zul Amali Che Kamaruddin
- Zul Fakar
- Zulfiqar Sandhu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
No full textThe International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) COVID-19 dataset is one of the largest international databases of prospectively collected clinical data on people hospitalized with COVID-19. This dataset was compiled during the COVID-19 pandemic by a network of hospitals that collect data using the ISARIC-World Health Organization Clinical Characterization Protocol and data tools. The database includes data from more than 705,000 patients, collected in more than 60 countries and 1,500 centres worldwide. Patient data are available from acute hospital admissions with COVID-19 and outpatient follow-ups. The data include signs and symptoms, pre-existing comorbidities, vital signs, chronic and acute treatments, complications, dates of hospitalization and discharge, mortality, viral strains, vaccination status, and other data. Here, we present the dataset characteristics, explain its architecture and how to gain access, and provide tools to facilitate its use
