10,525 research outputs found
Pattern based GUI testing for mobile applications
This paper presents a study aiming to assess the feasibility of using the Pattern Based GUI Testing approach, PBGT, to test mobile applications. PBGT is a new model based testing approach that aims to increase systematization, reusability and diminish the effort in modelling and testing. It is based on the concept of User Interface Test Patterns (UITP) that contain generic test strategies for testing common recurrent behaviour, the so-called UI Patterns, on GUIs through its possible different implementations after a configuration step. Although PBGT was developed having web applications in mind, it is possible to develop drivers for other platforms in order to test a wide set of applications. However, web and mobile applications are different and only the development of a new driver to execute test cases over mobile applications may not be enough. This paper describes a study aiming to identify the adaptations and updates the PBGT should undergo in order to test mobile applications. © 2014 IEEE
A Transcriptomic Approach to the Recruitment of Venom Proteins in a Marine Annelid
CEECIND/02699/2017The growing number of known venomous marine invertebrates indicates that chemical warfare plays an important role in adapting to diversified ecological niches, even though it remains unclear how toxins fit into the evolutionary history of these animals. Our case study, the Polychaeta Eulalia sp., is an intertidal predator that secretes toxins. Whole-transcriptome sequencing revealed proteinaceous toxins secreted by cells in the proboscis and delivered by mucus. Toxins and accompanying enzymes promote permeabilization, coagulation impairment and the blocking of the neuromuscular activity of prey upon which the worm feeds by sucking pieces of live flesh. The main neurotoxins ("phyllotoxins") were found to be cysteine-rich proteins, a class of substances ubiquitous among venomous animals. Some toxins were phylogenetically related to Polychaeta, Mollusca or more ancient groups, such as Cnidaria. Some toxins may have evolved from non-toxin homologs that were recruited without the reduction in molecular mass and increased specificity of other invertebrate toxins. By analyzing the phylogeny of toxin mixtures, we show that Polychaeta is uniquely positioned in the evolution of animal venoms. Indeed, the phylogenetic models of mixed or individual toxins do not follow the expected eumetazoan tree-of-life and highlight that the recruitment of gene products for a role in venom systems is complex.publishersversionpublishe
Developments in fish telemetry
Freshwater and marine ecosystems continue to be the focus of significant environmental change associated with an expanding human population and a rapidly changing climate. Many organisms within these environments, and fish in particular, are susceptible to increasing pressures, ranging from exploitation to modifications and loss of habitat. In order to manage and conserve these populations and protect biodiversity, these resources must be managed in a sympathetic and responsible manner. One biological tool that is progressively at the cutting edge of aquatic conservation is telemetry, which is increasingly being used by scientists to investigate fundamental aspects of animal biology in order to conserve and manage natural resources. The Sixth Conference on Fish Telemetry held in Europe was organised by the University of Evora and the Institute of Oceanography of the Faculty of Sciences of the University of Lisbon in June 2005. The Conference attracted 162 delegates from 25 countries stimulating a multidisciplinary approach to problem solving and further promoting technological development and innovation in the field of wildlife telemetry. The Conference provided an excellent forum for scientists and engineers to exchange views and to disseminate information on recent developments in order to support and provide the scientific basis for the sustainable management of aquatic resources. At the conference 74 oral and 56 poster contributions presented, and after review by members of the editorial board, 26 manuscripts were selected for inclusion within these proceedings. The selected papers are organised into four sections: (1) Human Impacts and Fisheries; (2) Migration and Behaviour; (3) Species Conservation and Habitat Rehabilitation; (4) Methodology and New Technology. We would like to thank the support of two institutions for the organization of the Conference, the University of Évora and the Institute of Oceanography (Faculty of Sciences, University of Lisbon), as well as the sponsorship of Administração do Porto de Sines, Ambassade de France au Portugal, Bacalhôa wines of Portugal, British Council (Portugal), Câmara Municipal de Sesimbra, Direccão-Geral das Pescas e Aquicultura, Fundação Luso-Americana, Fundação para a Ciência e a Tecnologia, Instituto da Água, Instituto de Turismo de Portugal, Instituto Italiano di Cultura Lisboa, Oceaná rio de Lisboa, and Região de Turismo da Costa Azul. We would also like to thank the members of the Conference Secretariat, Scientific and Organizing Committees, and all the attendees for contributing directly or indirectly to the success of this event. Special thanks go to 68 independent referees for helping to peer-review and select the manuscripts for the proceedings
Comparison of hip function and quality of life of total hip arthroplasty and resurfacing arthroplasty in the treatment of young patients with arthritis of the hip joint at 5 years
ObjectiveTo compare the medium-term clinical effectiveness of total hip arthroplasty and resurfacing arthroplasty.DesignSingle centre, two-arm, parallel group, assessor blinded, randomised controlled trial with 1:1 treatment allocation.SettingA large teaching hospital in England.Participants122 patients older than 18 years with severe arthritis of the hip joint, suitable for resurfacing arthroplasty of the hip. Patients were excluded if they were considered to be unable to adhere to trial procedures or complete questionnaires.InterventionsTotal hip arthroplasty (replacement of entire femoral head and neck); hip resurfacing arthroplasty (replacement of the articular surface of femoral head only, femoral neck remains intact). Both procedures replaced the articular surface of the acetabulum.OutcomesThe outcome measures were hip function assessed using the Oxford Hip Score (OHS) and health-related quality of life assessed using the EuroQol (EQ-5D). Patients were followed up annually for a minimum of 5 years. Outcome data were modelled using the generalised estimating equation methodology to explore temporal variations during follow-up.Results60 patients were randomly assigned to hip resurfacing arthroplasty and 62 to total hip arthroplasty. 95 (78%) of the 122 original study participants provided data at 5 years. There was a small decrease in both hip functions and quality of life in both groups of patients each year during the 5-year follow-up period. However, there was no evidence of a significant difference between treatments group in the OHS (P=0.333) or the EQ-5D (P=0.501).ConclusionsWe previously reported no difference in outcome in the first year after surgery. The current medium-term results also show no evidence of a difference in hip function or health-related quality of life in the 5 years following a total hip arthroplasty versus resurfacing arthroplasty.Trial registration numberISRCTN33354155. UKCRN 4093
The involvement of sphingolipids in apoptosis induced by acetic acid in yeast
This work was funded by FEDER through the program “Programa Operacional Factores de Competitividade-COMPETE” and by FCT (Fundação para a Ciência e Tecnologia) through the projects Pest-C/BIA/UI4050/2011 and FCOMP-01-0124-FEDER-007047. A.R. was supported by a FCT fellowship (FCOMP-01-0124-FEDER-007047)
Satellite-based feature extraction and multivariate time-series prediction of biotoxin contamination in shellfish
Shellfish production constitutes an important sector for the economy of many
Portuguese coastal regions, yet the challenge of shellfish biotoxin
contamination poses both public health concerns and significant economic risks.
Thus, predicting shellfish contamination levels holds great potential for
enhancing production management and safeguarding public health. In our study,
we utilize a dataset with years of Sentinel-3 satellite imagery for marine
surveillance, along with shellfish biotoxin contamination data from various
production areas along Portugal's western coastline, collected by Portuguese
official control. Our goal is to evaluate the integration of satellite data in
forecasting models for predicting toxin concentrations in shellfish given
forecasting horizons up to four weeks, which implies extracting a small set of
useful features and assessing their impact on the predictive models. We framed
this challenge as a time-series forecasting problem, leveraging historical
contamination levels and satellite images for designated areas. While
contamination measurements occurred weekly, satellite images were accessible
multiple times per week. Unsupervised feature extraction was performed using
autoencoders able to handle non-valid pixels caused by factors like cloud
cover, land, or anomalies. Finally, several Artificial Neural Networks models
were applied to compare univariate (contamination only) and multivariate
(contamination and satellite data) time-series forecasting. Our findings show
that incorporating these features enhances predictions, especially beyond one
week in lagoon production areas (RIAV) and for the 1-week and 2-week horizons
in the L5B area (oceanic). The methodology shows the feasibility of integrating
information from a high-dimensional data source like remote sensing without
compromising the model's predictive ability.Comment: 19 page
Aerodynamically-driven rupture of a liquid film by turbulent shear flow
The rupture of a liquid film due to co-flowing turbulent shear flows in the
gas phase is studied using a volume-of-fluid method. To simulate this
multiphase problem, we use a simplified numerical setup where the liquid film
is 'sandwiched' between two fully developed boundary layers from a turbulent
channel simulation. The film deforms and eventually ruptures within the shear
zone created by the co-flows. This efficient setup allows systematic variation
of physical parameters to gauge their role in the aerodynamically-driven
deformation and rupture of a liquid film under fully developed sheared
turbulence. The present work presents a detailed study of the developing
pressure field over the deforming film and related aerodynamic effects, as
previously suggested by other authors, in particular the role of the inviscid
lift and drag forces. A cumulative lift force is introduced to capture the
effect of the alternating pressure minima and maxima forming over the film
which amplify and eventually rupture the film. A velocity scale derived from
the lift-induced drag force reflects the state of the turbulent boundary layer
over the film and collapses the temporal development of this cumulative lift
force as well as the amplitude of film deformation with some success for the
different film thicknesses and Reynolds numbers.Comment: 23 pages, 17 figure
Lipovetsky, Gilles e Serroy, Jean (2010) [2007], O Ecrã Global. Cultura Mediática e Cinema na Era Hipermoderna, Lisboa: Edições 70
Em O Ecrã Global, Lipovetsky e Serroy mostram a importância do ecrã, e da cultura que o rodeia, nos tempos actuais..
Miranda, Bragança de (2008), Envios. Uma Experimentação Filosófica na Internet, Lisboa: Nova Vega
É com Envios que Bragança de Miranda se entretém na Internet. São fluxos que decorrem da sua relação com o ecrã do computador, numa fusão entre os seus pensamentos, prosas e imagens sobre o mundo..
Study of the Saldanha Massif (MAR, 36 degrees 34 ' N): Constrains from rock magnetic and geophysical data
We present a study of the magnetic properties of a group of basalt samples from the Saldanha Massif (Mid-Atlantic Ridge - MAR - 36degrees 33' 54" N, 33degrees 26' W), and we set out to interpret these properties in the tectono-magmatic framework of this sector of the MAR. Most samples have low magnetic anisotropy and magnetic minerals of single domain grain size, typical of rapid cooling. The thermomagnetic study mostly shows two different susceptibility peaks. The high temperature peak is related to mineralogical alteration due to heating. The low temperature peak shows a distinction between three different stages of low temperature oxidation: the presence of titanomagnetite, titanomagnetite and titanomaghemite, and exclusively of titanomaghemite. Based on established empirical relationships between Curie temperature and degree of oxidation, the latter is tentatively deduced for all samples. Finally, swath bathymetry and sidescan sonar data combined with dive observations show that the Saldanha Massif is located over an exposed section of upper mantle rocks interpreted to be the result of detachment tectonics. Basalt samples inside the detachment zone often have higher than expected oxidation rates; this effect can be explained by the higher permeability caused by the detachment fault activity
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