2 research outputs found
Delivery systems in nanocosmeceuticals
Today, the growth of the cosmetic industry and
dramatic technological advances have led to the creation
of functional cosmetical products that enhance beauty
and health. Such products can be defined as topical cosmetic drugs to improve health and beauty functions or
benefits. Implementing nanotechnology and advanced
engineering in these products has enabled innovative
product formulations and solutions. The search included
organic molecules used as cosmeceuticals and nanoparticles (NPs) used in that field. As a result, this document
analyses the use of organic and inorganic particles, metals,
metal-oxides, and carbon-based particles. Additionally,
this document includes lipid and nanoparticles solid
lipid systems. In conclusion, using NPs as vehicles of
active substances is a potential tool for transporting
active ingredients. Finally, this review includes the
nanoparticles used in cosmeceuticals while presenting
the progress made and highlighting the hidden challenges associated with nanocosmeceuticals
Composite scaffolds of chitosan/polycaprolactone functionalized with protein of Mytilus californiensis for bone tissue regeneration
Nowadays, the treatment for bone damage remains a significant challenge. As a result, the development of bioactive three-dimensional scaffolds for bone regeneration has become a key area of study within tissue engineering. This research is focused on the evaluation of the properties of Chitosan (Ch)/Polycaprolactone (PCL) scaffolds with the Mytilus californiensis protein by Thermally Induced Phase Separation (TIPS). This study used the extrapalleal fluid protein from Mytilus californiensis because it increases biological processes that support bone regeneration. Two methodologies were used for the scaffolds functionalization: (I) an immersion process in a solution with the protein and (II) the protein direct addition during the scaffold synthesis. The scaffolds were analyzed by Fourier Transformed Infrared Spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), and Mechanical Compression test to determine the composition, morphology, and mechanical properties of each material. In vitro analysis of biodegradation, bioactivity, and biocompatibility were also performed. The scaffolds with the protein added directly presented superior properties in the tests of bioactivity and cellular proliferation, making these composites attractive for the area of bone regeneration