9 research outputs found
Modelling of the 3D structure of IFN–alpha–k, characterization of its surface molecular properties and preliminary evaluation of its interactions with beta-cyclodextrin derivatives
No full text
Ubidecarenone nanoemulsified composite systems
No full textThe nanoemulsified composite (NEC(TM)) delivery system is a patented technology based on the incorporation of a double microemulsion into microporous carrier. This approach was applied on the very water insoluble ubidecarenone drug. The resulting composite powder showed good technological properties such as flowability; also good stability was evidentiated, with size of the nano-droplets released from the systems maintained equal to the starting size also after a long storage. Furthermore very good biopharmaceutical properties were originated, with water solubility concentrations up to 50-fold higher than pure ubidecarenone and oral absorption in rats up to three-fold greater than standard commercial products in terms of plasma levels and AUC. (C) 2004 Elsevier B.V. All rights reserved
Modelling of the 3-D structure of human interferon a-k and characterization of its surface molecular properties
No full textMicroparticles based on hybrid polymeric materials for controlled release of biologically active molecules. A process for preparing the same and their uses for in vivo and in vitro therapy, prophylaxis and diagnostics
No full textDevelopment of Cyclosporine-A in nanoemulsified composites (NECTM)
No full textFormulation and characterization approach of cyclospirin-A in nanoemulsified composites
Solid double microemulsions for improved absorption of scarcely bioavailable drugs
No full textSolid double microemulsions for improved absorption of scarcely bioavailable drug
