448 research outputs found
Towards a Self-Organizing Digital Business Ecosystem: Examining IT-Enabled Boundary Spanning Practice of China’s LeEco
The emergence of digital business platforms, ecosystems and non-linear value chains fosters hyper-connections among human actors, organizations, and processes. Such digital moves have brought cross-industry convergence and the blurring of business ecosystem boundaries, bringing about the possibility of overlapping business ecosystems, generating complex socio-technical issues. In this research-in-progress paper, we unpack the processes of how China’s LeEco develop from an emergent digital platform to a self-organizing digital business ecosystem. Drawing on theoretical notions of boundary spanning practice, we posit that towards a self-organizing digital business ecosystem, managers must seek to instill a conducive environment that reinforces, reciprocates and reproduces digital infrastructure through organizational coalition, congruence and hybridity respectively. Towards theoretical and practitioner contributions, ongoing analysis seeks to unpack the process of managing overlapping digital business ecosystems, the conditions under which they operate, the role of digital infrastructure in transition across organizational forms, the implications and outcomes
Tungsten silicide films for microwave kinetic inductance detectors
Microwave Kinetic Inductance Detectors (MKIDs) provide highly multiplexed
arrays of detectors that can be configured to operate from the sub-millimeter
to the X-ray regime. We have examined two tungsten silicide alloys (W5Si3 and
WSi2), which are dense alloys that provide a critical temperature tunable with
composition, large kinetic inductance fraction, and high normal-state
resistivity. We have fabricated superconducting resonators and provide
measurement data on critical temperature, surface resistance, quality factor,
noise, and quasiparticles lifetime. Tungsten silicide appears to be promising
for microwave kinetic inductance detectors
In situ spectroscopic ellipsometry as a surface-sensitive tool to probe thin film growth
Multimodal Identification of Alzheimer's Disease: A Review
Alzheimer's disease is a progressive neurological disorder characterized by
cognitive impairment and memory loss. With the increasing aging population, the
incidence of AD is continuously rising, making early diagnosis and intervention
an urgent need. In recent years, a considerable number of teams have applied
computer-aided diagnostic techniques to early classification research of AD.
Most studies have utilized imaging modalities such as magnetic resonance
imaging (MRI), positron emission tomography (PET), and electroencephalogram
(EEG). However, there have also been studies that attempted to use other
modalities as input features for the models, such as sound, posture,
biomarkers, cognitive assessment scores, and their fusion. Experimental results
have shown that the combination of multiple modalities often leads to better
performance compared to a single modality. Therefore, this paper will focus on
different modalities and their fusion, thoroughly elucidate the mechanisms of
various modalities, explore which methods should be combined to better harness
their utility, analyze and summarize the literature in the field of early
classification of AD in recent years, in order to explore more possibilities of
modality combinations
Beyond Survival Effects of Vitrification-Warming on Epigenetic Modification and Maternal Transcripts of Oocytes
Oocyte vitrification-warming is a worldwide used technique for human fertility preservation. The question of whether the potential risk is associated with this specific procedure remains unresolved. As a fundamental factor of development, oocytes play an important role in early embryonic development, including epigenetic reprogramming and maternal-to-zygotic transition (MZT), that can develop to term. Vitrification, as a significant stressor, appears to have a significant impact on epigenetic modifiers and maternal transcripts of the oocyte, which ultimately results in lower developmental potential. Due to the rapidly evolving single-cell multi-omics sequencing, there have been many advances in this field. We will discuss recent progress in the impact of oocyte vitrification on epigenetic modification and maternal transcripts in this manuscript, hoping to provide a theoretical basis for the optimization and improvement of vitrification-warming technology
Potential Retinoid X Receptor Agonists for Treating Alzheimer’s Disease from Traditional Chinese Medicine
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