83 research outputs found
Pragmatica en qve sv Magestad manda prohibir el vso de la Moneda de vellon de Molinos, que en estos Reynos corria con el valor de dos maravedis, dandose satisfaccion por quenta de la Real Hazienda
Caplletra xil. ornada a l'inici del textPragmàtica, 1680-05-23 : "EN la Villa de Madrid à veinte y tres dias del més de Mayo de mil y seiscientos y ochenta años"ReclamsSign.: A3Verso de la portada: "Diego de Vrueña Navamuel"Pragmàtica en la qual sa Majestat ordena prohibir l'ús de la moneda de vellon de Molinos, que en aquests regnes corria amb valor de dos maravedis, a càrrec de la Reial Hisenda.
Caracterización litológica y mineralogica de los materiales permo-triásicos de Castellón utilizados como materia prima cerámica : la arcilla de Moró
Las lutitas de edad Pérmica que se utilizan como materia prima en la industria azulejera de Castellón se conocen en el sector cerámico como arcilla de Moró. En el presente trabajo se describen las características litológicas y composicionales de estas lutitas con el objetivo de establecer las variaciones en composición a lo largo de la serie estratigráfica tipo. Los resultados muestran una composición mineralógica de la roca total muy uniforme, formada esencialmente por cuarzo, filosilicatos y hematites. Ocasionalmente y en proporciones por debajo del 5% aparece también feldespato potásito, dolomita y calcita. La asociación de minerales de la arcilla está formada por illita ± caolinita ± clorita ± interestratificado illita-esmectita ± interestratificado clorita-esmectita y muestra un patrón de distribución sedimentario. Los resultados obtenidos ponen de manifiesto la importancia del análisis mineralógico en la caracterización de las materias primas y, por tanto, en el control de sus propiedades cerámicas y de los procesos productivos relacionados.The aim of this work is to establish the mineralogical (XRD) composition of the Permo-Triassic claystone known as Moró clay. Particular emphasis is placed on the compositional variations along the litostratigraphic section. Bulk rock XRD analysis shows a homogeneous composition dominated by quartz, phyllosilicates and hematite. Minor components (<5%) include potassium feldspar, dolomite and calcite. The clay minerals assemblage is formed by illite ± kaolin ± chlorite ± mixed-layer illite-smectite ± mixed-layer chlorite-smectite and reveals a sedimentary distribution pattern. The study of the lithological section allows the identification and valuation of changes in the mineralogical characteristics of the raw material. Results provide evidence for the importance of mineralogical analysis in the control of raw materials and hence their use in industrial processes
Cedvla Real en qve su Magestad manda se observe, y guarde la moderacion de alquileres de casas, y precios de todos generos comerciables &c
Caplletra xil. ornada a l'inici del textConté índex de preus signat per: "Diego de Vrueña Navamuel" y "Miguel Fernandez de Noriega"Creu i escut reial xil. a port.Publicada: "EN la Villa de Madrid à catorce dias del més de Diziembre de mil y seiscientos y ochenta años"ReclamsSign.: A-Z, Aa-BbCèdula Real en que sa Majestat ordena que s'observi, i guardi la moderació de lloguers de cases, i preus de tots gèneres comerciables.
Por Carlos Lazer, clerigo, contra Vicente Armengot [Texto impreso] : sobre el obtento del beneficio... fundado en la Iglesia Parroquial de San Miguel Arcangel de la presente ciudad, baxo la advocación de la Purissima... que vaca por muerte del Doctor Guerola
Hay un ejemplar encuadernado con XVII/1212Sing.: [A]2, B-L2Port. con orla y grab. xil
Characterization of postintensive care syndrome in a prospective cohort of survivors of COVID-19 critical illness : a 12-month follow-up study
Purpose: Studies integrating an exhaustive longitudinal long-term follow-up of postintensive care syndrome (PICS) in critically ill COVID-19 survivors are scarce. We aimed to 1) describe PICS-related sequelae over a 12-month period after intensive care unit (ICU) discharge, 2) identify relevant demographic and clinical factors related to PICS, and 3) explore how PICS-related sequelae may influence health-related quality of life (HRQoL) in critically ill COVID-19 survivors. Methods: We conducted a prospective cohort study in adult critically ill survivors of SARS-CoV-2 infection that did or did not need invasive mechanical ventilation (IMV) during the COVID-19 pandemic in Spain (March 2020 to January 2021). We performed a telemedicine follow-up of PICS-related sequelae (physical/functional, cognitive, and mental health) and HRQoL with five data collection points. We retrospectively collected demographic and clinical data. We used multivariable mixed-effects models for data analysis. Results: We included 142 study participants in the final analysis, with a median [interquartile range] age of 61 [53-68] yr; 35% were female and 59% needed IMV. Fatigue/dyspnea, pain, impaired muscle function, psychiatric symptomatology and reduced physical HRQoL were prominent sequelae early after ICU discharge. Over the 12-month follow-up, functionality and fatigue/dyspnea improved progressively, while pain remained stable. We observed slight fluctuations in anxiety symptoms and perception of cognitive deficit, whereas posttraumatic stress disorder (PTSD) and depressive symptoms improved, with a mild rebound at the end of the follow-up. Female sex, younger age, and the need for IMV were risk factors for PICS, while having higher cognitive reserve was a potential protective factor. Physical HRQoL scores showed a general improvement over time, whereas mental HRQoL remained stable. Shorter ICU stay, better functionality, and lower scores for fatigue/dyspnea and pain were associated with better physical HRQoL, while lower scores for anxiety, depression, and PTSD were associated with better mental HRQoL. Conclusions: Postintensive care syndrome was common in COVID-19 critical illness survivors and persisted in a significant proportion of patients one year after ICU discharge, impacting HRQoL. The presence of risk factors for PICS may identify patients who are more likely to develop the condition and who would benefit from more specific and closer follow-up after ICU admission. Study registration: ClinicalTrials.gov (NCT04422444); first submitted 9 June 2020
Application of Multi-core and GPU Architectures on Signal Processing: Case Studies
In this article part of the techniques and developments we are carrying out within the INCO2 group are reported. Results follow the interdisciplinary approach with which we tackle signal processing applications. Chosen case studies show different stages of development: We present algorithms already completed which are being used in practical applications as well as new ideas that may represent a starting point, and which are expected to deliver good results in a short and medium term
Key epidemiological indicators and spatial autocorrelation patterns across five waves of COVID-19 in Catalonia
This research studies the evolution of COVID-19 crude incident rates, effective reproduction number R(t) and their relationship with incidence spatial autocorrelation patterns in the 19 months following the disease outbreak in Catalonia (Spain). A cross-sectional ecological panel design based on n = 371 health-care geographical units is used. Five general outbreaks are described, systematically preceded by generalized values of R(t) > 1 in the two previous weeks. No clear regularities concerning possible initial focus appear when comparing waves. As for autocorrelation, we identify a wave’s baseline pattern in which global Moran’s I increases rapidly in the first weeks of the outbreak to descend later. However, some waves significantly depart from the baseline. In the simulations, both baseline pattern and departures can be reproduced when measures aimed at reducing mobility and virus transmissibility are introduced. Spatial autocorrelation is inherently contingent on the outbreak phase and is also substantially modified by external interventions affecting human behavior
Stellar multiplicity and stellar rotation::Insights from APOGEE
We measure rotational broadening in spectra taken by the Apache Point
Observatory Galactic Evolution Experiment (APOGEE) survey to characterise the
relationship between stellar multiplicity and rotation. We create a sample of
2786 giants and 24 496 dwarfs with stellar parameters and multiple radial
velocities from the APOGEE pipeline, projected rotation speeds \vsini\
determined from our own pipeline, and distances, masses, and ages measured by
Sanders \& Das. We use the statistical distribution of the maximum shift in the
radial velocities, \drvm, as a proxy for the close binary fraction to explore
the interplay between stellar evolution, rotation, and multiplicity. Assuming
that the minimum orbital period allowed is the critical period for Roche Lobe
overflow and rotational synchronization, we calculate theoretical upper limits
on expected \vsini\ and \drvm\ values. These expectations agree with the
positive correlation between the maximum \drvm\ and \vsini\ values observed in
our sample as a function of \logg. We find that the fast rotators in our sample
have a high occurrence of short-period ()
companions. We also find that old, rapidly-rotating main sequence stars have
larger completeness-corrected close binary fractions than their younger peers.
Furthermore, rapidly-rotating stars with large \drvm\ consistently show
differences of 1-10 Gyr between the predicted gyrochronological and measured
isochronal ages. These results point towards a link between rapid rotation and
close binarity through tidal interactions. We conclude that stellar rotation is
strongly correlated with stellar multiplicity in the field, and caution should
be taken in the application of gyrochronology relations to cool stars.Comment: 12 pages, 9 figures; accepted by MNRA
Galectin-1 prevents pathological vascular remodeling in atherosclerosis and abdominal aortic aneurysm
Pathological vascular remodeling is the underlying cause of atherosclerosis and abdominal aortic aneurysm (AAA). Here, we analyzed the role of galectin-1 (Gal-1), a β-galactoside-binding protein, as a therapeutic target for atherosclerosis and AAA. Mice lacking Gal-1 (Lgals1 −/− ) developed severe atherosclerosis induced by pAAV/D377Y-mPCSK9 adenovirus and displayed higher lipid levels and lower expression of contractile markers of vascular smooth muscle cells (VSMCs) in plaques than wild-type mice. Proteomic analysis of Lgals1 −/− aortas showed changes in markers of VSMC phenotypic switch and altered composition of mitochondrial proteins. Mechanistically, Gal-1 silencing resulted in increased foam cell formation and mitochondrial dysfunction in VSMCs, while treatment with recombinant Gal-1 (rGal-1) prevented these effects. Furthermore, rGal-1 treatment attenuated atherosclerosis and elastase-induced AAA, leading to higher contractile VSMCs in aortic tissues. Gal-1 expression decreased in human atheroma and AAA compared to control tissue. Thus, Gal-1-driven circuits emerge as potential therapeutic strategies in atherosclerosis and AAA. Galectin-1 plays an essential role in prevention of atherosclerosis and abdominal aortic aneurysm
Seed storage conditions change the germination pattern of clonal growth plants in Mediterranean salt marshes.
8 páginas, 4 tablas, 8 figuras.The effect of salinity level and extended exposure to different salinity and flooding conditions on germination patterns of three saltmarsh clonal growth plants (Juncus subulatus, Scirpus litoralis, and S. maritimus) was studied. Seed exposure to extended flooding and saline conditions significantly affected the outcome of the germination process in a different, though predictable, way for each species, after favorable conditions for germination were restored. Tolerance of the germination process was related to the average salinity level measured during the growth/germination season at sites where established individuals of each species dominated the species cover. No relationship was found between salinity tolerance of the germination process and seed response to extended exposure to flooding and salinity conditions. The salinity response was significantly related to the conditions prevailing in the habitats of the respective species during the unfavorable (nongrowth/nongermination) season. Our results indicate that changes in salinity and hydrology while seeds are dormant affect the outcome of the seed-bank response, even when conditions at germination are identical.
Because these environmental-history-dependent responses differentially affect seed germination, seedling density, and probably sexual recruitment in the studied and related species, these influences should be considered for wetland restoration and managementFinancial support from the Spanish Ministry of the Environment (MMA, project 05/99) and the Junta de Andalucía (research group 4086)enabled us to carry out the present work.Peer reviewe
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