Additional file 2: of Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes

Figure S1. Genotype at SNP rs174537 is associated with circulating n-6 LC-PUFAs. Serum (cohort 1) and plasma (cohort 2) n-6 LC-PUFA levels are illustrated as mean ± SEM. (A) %DGLA, (B) %ARA, and (C) ARA/DGLA ratio. Asterisks represent statistically significant differences between genotypes (p < 0.05). (TIFF 175 kb

Additional file 3: of Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes

Table S2. Summary of plasma and serum fatty acids. Medians and IQR reported. Definitions of SFAs, MUFAs, PUFAs, and n-3/n-6 ratios are provided at the bottom of the table. (DOCX 18 kb

Additional file 3: Table S1. of Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes

List of SNPs with meta-analysis p-value less than 10–4. (XLSX 190 kb

Additional file 1: Table S4. of Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes

Meta-analysis of 130 HU CAC scores in AA-DHS and JHS. (XLSX 230 kb

Additional file 2: Table S3. of Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes

Replication of AA-DHS admixture mapping results in JHS. (XLSX 11 kb

Additional file 1: of Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos

Supplementary Tables. (ODS 129 kb

Additional file 2: of Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos

Supplementary Figures. (DOCX 112 kb

Additional file 1: of Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility

Supplemental Data: Table S1. The clinical characteristics of samples in each JIA cohort. Table S2. Genome-wide significant associations at the HLA locus (p < 5×10-8 in the discovery cohort).Table S3. Association results for top SNPs in known JIA associated genes PTPN22, IL2RA, ANTXR2. TableS4. The most significantly associated SNPs at CXCR4 locus on chromosome 2q22.1. Table S5 . Genomewideassociation results for imputed SNPs (p < 1×10-4 in combined analysis) in the vicinity of CXCR4 in our JIA cohort. Table S6. Primers used in Sanger sequencing validation of rare variants at CXCR4 locus. Figure S1. Genome-wide association results for JIA. Figure S2. Regional association plot for the 2q22.1 region. Figure S3. CXCR4 tissue-specific gene expression levels. Figure S4. CXCR4 expression levels stratified by SNP genotype. (DOC 466 kb

This figure shows the results of the genome-wide linkage scan for eGFR in population-specific and population-combined analysis that accounted the covariate effects of BMI and diabetes duration.

<p>AA-African Americans; AI-American Indians; EA-European Americans; MA-Mexican Americans, cM-Centi Morgans.</p

Summary of analyzed pedigrees and genotyped individuals (N).

<p>Summary of analyzed pedigrees and genotyped individuals (N).</p